Actemra combined with Folic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 1/1/2008 Female 123 lb 9/25/2009 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 123 lb 10/16/2009 Consumer Brazil
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 11/1/2009 Female 2/11/2010 Physician Australia
Primary
Concomitant
Cardiac Failure Death 3/1/2010 Male 132 lb 3/8/2010 Other Health Professional Belgium
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/1/2010 Female 190 lb 3/10/2010 Physician Belgium
Primary
Secondary
Concomitant
Shock Hospitalization 2/24/2010 Female 97 lb 3/19/2010 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/4/2010 Female 104 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 1/5/2010 Female 204 lb 3/22/2010 Consumer Spain
Primary
Concomitant
Shock Hospitalization 2/24/2010 74 Female 97 lb 4/9/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/15/2010 Physician Japan
Primary
Concomitant
Gastritis Hospitalization 4/4/2010 40 Female 4/20/2010 Other Health Professional Colombia
Primary
Concomitant
Pleural Effusion Life Threatening 2/16/2010 72 Male 118 lb 4/23/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 4/23/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/28/2010 78 Female 128 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 4/17/2010 73 Male 128 lb 5/4/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 5/15/2009 58 Female 106 lb 5/6/2010 Physician Japan
Primary
Concomitant
Gastritis Hospitalization 4/4/2010 40 Female 5/10/2010 Other Health Professional Colombia
Primary
Concomitant
Intestinal Perforation Other Serious 3/29/2010 61 Female 5/14/2010 Pharmacist Australia
Primary
Concomitant
Myocardial Infarction Life Threatening 2/16/2010 72 Male 118 lb 5/20/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Other Serious 5/8/2010 47 Female 235 lb 5/11/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 6/25/2010 55 Female 155 lb 7/9/2010 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 5/26/2010 57 Female 7/12/2010 Other Health Professional United States
Primary
Concomitant
Gait Disturbance Other Serious 6/1/2010 41 Female 126 lb 7/28/2010 Physician Brazil
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 6/1/2010 41 Female 126 lb 8/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Menorrhagia Other Serious 11/25/2008 40 Female 126 lb 8/5/2010 Physician Brazil
Primary
Secondary
Concomitant
Menorrhagia Other Serious 6/1/2010 41 Female 126 lb 8/11/2010 Physician Brazil
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 6/1/2010 57 Female 8/12/2010 Other Health Professional Colombia
Primary
Concomitant
Vomiting Other Serious 7/29/2010 28 Female 8/19/2010 Other Health Professional Colombia
Primary
Concomitant
Optic Neuritis Other Serious 8/3/2010 67 Female 180 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Menorrhagia Other Serious 11/25/2008 40 Female 126 lb 8/30/2010 Physician Brazil
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/26/2010 57 Female 191 lb 9/1/2010 Other Health Professional United States
Primary
Concomitant
Menorrhagia Other Serious 6/1/2010 41 Female 126 lb 9/3/2010 Physician Brazil
Primary
Secondary
Concomitant
Optic Neuritis Disability 8/3/2010 67 Female 180 lb 9/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 7/29/2010 28 Female 9/9/2010 Other Health Professional Colombia
Primary
Concomitant
Menorrhagia Other Serious 11/25/2008 40 Female 126 lb 9/13/2010 Physician Brazil
Primary
Secondary
Concomitant
Chills 8/13/2010 51 Female 120 lb 9/15/2010 Physician Hong Kong
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/3/2010 81 Female 105 lb 9/17/2010 Consumer United States
Primary
Concomitant
Menorrhagia Other Serious 6/1/2010 41 Female 126 lb 9/17/2010 Physician Brazil
Primary
Secondary
Concomitant
Optic Neuritis Disability 8/2/2010 67 Female 180 lb 9/29/2010 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious Female 11/23/2010 Physician Australia
Primary
Concomitant
Pancreatitis Hospitalization 8/31/2010 28 Female 11/24/2010 Physician Argentina
Primary
Concomitant
Oral Mucosal Eruption Hospitalization 8/1/2010 63 Female 12/20/2010 Consumer Colombia
Primary
Concomitant
Oral Mucosal Eruption Hospitalization 8/1/2010 63 Female 12/27/2010 Consumer Colombia
Primary
Concomitant
Pneumonia Hospitalization 12/12/2010 47 Male 12/30/2010 Other Health Professional Colombia
Primary
Concomitant
Arrhythmia Hospitalization 12/12/2010 47 Male 1/5/2011 Other Health Professional Colombia
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/2/2011 64 Female 182 lb 1/24/2011 Other Health Professional United States
Primary
Concomitant
Blood Cholesterol Increased 63 Female 1/20/2011 Other Health Professional United States
Primary
Concomitant
Eye Haemorrhage Hospitalization 1/14/2011 37 Female 2/10/2011 Other Health Professional Colombia
Primary
Concomitant
Myocardial Infarction Hospitalization 1/12/2011 65 Female 132 lb 2/18/2011 Physician Israel
Primary
Concomitant
Embolism Arterial Hospitalization 2/6/2011 41 Female 161 lb 2/25/2011 Physician United States
Primary
Concomitant
Polyneuropathy Other Serious 6/1/2010 68 Female 2/28/2011 Physician Brazil
Primary
Concomitant
Hormone Level Abnormal Hospitalization 1/22/2011 70 Male 3/10/2011 Consumer Russian Federation
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/6/2011 41 Female 161 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 1/22/2011 70 Male 3/11/2011 Consumer Russian Federation
Primary
Concomitant
Headache Other Serious Female 3/11/2011 Other Health Professional Australia
Primary
Concomitant
Leukopenia Other Serious 1/22/2011 69 Male 159 lb 3/30/2011 Physician Russian Federation
Primary
Concomitant
Chills Other Serious Female 3/30/2011 Other Health Professional Australia
Primary
Concomitant
Back Pain Other Serious 2/22/2011 41 Female 190 lb 4/8/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2011 78 Male 217 lb 4/13/2011 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/28/2010 54 Female 141 lb 4/13/2011 Physician Japan
Primary
Concomitant
Rash Macular Hospitalization 8/1/2010 57 Female 128 lb 4/14/2011 Consumer Brazil
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 12/4/2009 65 Male 150 lb 4/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Face Oedema Other Serious Female 4/15/2011 Other Health Professional Australia
Primary
Concomitant
Hodgkin's Disease Hospitalization 5/28/2010 54 Female 141 lb 4/19/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/6/2011 41 Female 161 lb 4/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 4/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cellulitis Other Serious 4/22/2010 62 Male 121 lb 4/29/2011 Physician Japan
Primary
Concomitant
Endophthalmitis Disability 12/16/2010 72 Female 104 lb 4/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 8/1/2010 57 Female 128 lb 5/2/2011 Physician Brazil
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 6/1/2010 68 Female 5/4/2011 Consumer Brazil
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 3/7/2009 62 Male 274 lb 5/6/2011 Physician United States
Primary
Concomitant
Back Pain Hospitalization 12/15/2009 59 Female 158 lb 5/6/2011 Physician United States
Primary
Concomitant
Diarrhoea 2/1/2011 36 Female 5/6/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 5/28/2010 54 Female 104 lb 5/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/29/2010 60 Female 115 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/1/2011 63 Female 156 lb 5/9/2011 Physician United States
Primary
Concomitant
Breast Cancer In Situ Other Serious 8/23/2010 52 Female 115 lb 5/10/2011 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 1/20/2011 63 Female 5/12/2011 Physician France
Primary
Concomitant
Cellulitis Hospitalization 6/4/2008 55 Female 117 lb 5/13/2011 Physician Japan
Primary
Secondary
Concomitant
Colon Cancer Hospitalization 9/14/2009 71 Male 200 lb 5/16/2011 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 2/10/2010 54 Female 132 lb 5/17/2011 Physician Russian Federation
Primary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 5/31/2011 Other Health Professional Japan
Primary
Concomitant
Patella Fracture Hospitalization 12/16/2009 64 Female 82 lb 6/3/2011 Physician Japan
Primary
Concomitant
Hepatitis Hospitalization 5/24/2011 16 Female 88 lb 6/6/2011 Consumer Lebanon
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/1/2011 57 Male 6/6/2011 Physician France
Primary
Concomitant
Gastric Cancer Death Male 6/6/2011 Other Health Professional Japan
Primary
Concomitant
Lens Disorder Disability 1/20/2011 59 Female 174 lb 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Aortic Dissection Life Threatening 5/2/2011 75 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Gastric Cancer Death 4/24/2011 74 Male 95 lb 6/16/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/18/2011 39 Female 132 lb 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 10/5/2010 66 Male 6/20/2011 Physician France
Primary
Concomitant
Infusion Related Reaction Hospitalization 12/4/2009 65 Male 150 lb 6/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Macular Hospitalization 8/1/2010 57 Female 128 lb 6/22/2011 Consumer Brazil
Primary
Secondary
Concomitant
Erythema Hospitalization 9/1/2010 39 Female 117 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Other Serious 5/24/2011 16 Female 88 lb 6/27/2011 Physician Lebanon
Primary
Secondary
Concomitant
Eye Pain Other Serious 1/20/2011 59 Female 174 lb 6/28/2011 Physician United Kingdom
Primary
Concomitant
Osteoarthritis Other Serious 5/19/2011 77 Female 132 lb 6/29/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 6/26/2010 77 Female 101 lb 7/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 1/22/2011 69 Male 159 lb 7/5/2011 Physician Russian Federation
Primary
Concomitant
Malignant Ascites Death 11/24/2010 73 Male 95 lb 7/5/2011 Physician Japan
Primary
Concomitant
Knee Arthroplasty Other Serious 1/1/2009 58 Female 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 9/1/2010 39 Female 117 lb 7/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 3/1/2011 56 Male 331 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Pleurisy Hospitalization 6/1/2011 65 Female 97 lb 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Eye Infection Other Serious 50 Female 122 lb 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 9/1/2010 39 Female 117 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Hereditary Sideroblastic Anaemia Other Serious 31 Female 7/26/2011 Physician Japan
Primary
Concomitant
Mouth Ulceration Other Serious Female 7/27/2011 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/18/2011 39 Female 132 lb 7/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 5/24/2011 16 Female 88 lb 8/1/2011 Physician Lebanon
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 8/5/2011 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Hospitalization 11/4/2010 60 Female 101 lb 8/15/2011 Other Health Professional Japan
Primary
Concomitant
Dyspnoea Hospitalization 6/24/2011 59 Female 8/17/2011 Physician France
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/1/2010 64 Female 110 lb 8/18/2011 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Fluctuation Other Serious 8/1/2010 57 Female 128 lb 9/7/2011 Consumer Brazil
Primary
Secondary
Concomitant
Ulna Fracture Hospitalization 2/18/2010 58 Female 119 lb 9/12/2011 Other Health Professional Japan
Primary
Concomitant
Blood Blister Other Serious 5/1/2010 64 Female 110 lb 9/12/2011 Other Health Professional Japan
Primary
Concomitant
Paraesthesia Oral Other Serious 8/15/2011 59 Female 9/14/2011 Other Health Professional Australia
Primary
Concomitant
Rash Hospitalization 5/13/2011 58 Female 255 lb 9/23/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Pain Other Serious 6/1/2011 67 Male 155 lb 9/23/2011 Consumer United States
Primary
Concomitant
Lymphadenectomy Other Serious 9/1/2011 41 Female 126 lb 9/23/2011 Physician Italy
Primary
Concomitant
Vasculitis Hospitalization 10/17/2009 59 Female 9/29/2011 Ireland
Primary
Concomitant
Cerebral Haemorrhage Other Serious 12/13/2010 50 Female 9/30/2011 Japan
Primary
Concomitant
Arthralgia Hospitalization 1/14/2011 37 Female 10/4/2011 Consumer Colombia
Primary
Concomitant
Lung Adenocarcinoma Stage Ii Life Threatening 10/16/2009 64 Female 150 lb 10/10/2011 Physician Brazil
Primary
Concomitant
Colitis Ulcerative Other Serious 9/8/2011 40 Female 209 lb 10/11/2011 Other Health Professional United States
Primary
Concomitant
Influenza Disability 12/1/2010 67 Female 10/11/2011 Brazil
Primary
Secondary
Concomitant
Abdominal Pain Life Threatening 7/6/2011 56 Female 163 lb 10/12/2011 United States
Primary
Concomitant
Cerebral Infarction Death 7/27/2010 68 Female 10/13/2011 Japan
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 7/29/2011 53 Female 10/13/2011 Consumer United Kingdom
Primary
Concomitant
Dyspepsia Other Serious 7/7/2011 62 Female 200 lb 10/14/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 7/1/2011 49 Male 176 lb 10/14/2011 Canada
Primary
Concomitant
Hepatic Steatosis Other Serious 3/16/2011 54 Female 165 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pain Hospitalization 8/1/2010 57 Female 128 lb 10/17/2011 Brazil
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 8/9/2010 69 Female 119 lb 10/17/2011 Canada
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 41 Female 163 lb 10/17/2011 Consumer Brazil
Primary
Concomitant
Arthralgia Other Serious 8/18/2011 25 99 lb 10/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/1/2011 67 Male 154 lb 10/18/2011 Consumer Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/16/2011 57 Female 240 lb 10/18/2011 Physician Canada
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/13/2011 58 Female 255 lb 10/18/2011 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 12/16/2009 64 Female 82 lb 10/18/2011 Japan
Primary
Concomitant
Dyspnoea Other Serious Female 159 lb 10/21/2011 Physician Sweden
Primary
Concomitant
Vertigo Hospitalization 2/28/2010 60 Female 132 lb 10/26/2011 Physician Japan
Primary
Concomitant
Cardiac Arrest Death 3/28/2011 56 Male 144 lb 11/1/2011 Physician Mexico
Primary
Secondary
Concomitant
Spinal Compression Fracture Life Threatening 7/22/2010 77 Female 11/2/2011 Japan
Primary
Secondary
Concomitant
Coagulation Factor Deficiency Hospitalization 9/2/2008 47 Male 11/3/2011 Japan
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 9/14/2011 59 Female 215 lb 11/4/2011 Consumer Canada
Primary
Concomitant
Acute Coronary Syndrome Life Threatening 1/2/2011 64 Female 162 lb 11/4/2011 Other Health Professional United States
Primary
Concomitant
Eructation Other Serious 7/7/2011 62 Female 200 lb 11/4/2011 Physician United States
Primary
Concomitant

Drug Data