Actemra combined with Enbrel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypersensitivity Other Serious Female 159 lb 2/22/2010 Consumer Brazil
Primary
Secondary
Concomitant
Hypersensitivity Other Serious Female 159 lb 3/11/2010 Consumer Brazil
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 11/3/2009 Male 146 lb 3/16/2010 Physician France
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 2/16/2010 72 Male 118 lb 4/23/2010 Physician Japan
Primary
Concomitant
Mesothelioma Other Serious 3/15/2010 61 Male 9/13/2010 Physician Switzerland
Primary
Concomitant
Low Density Lipoprotein Increased Life Threatening 4/14/2010 53 Female 128 lb 10/8/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious Female 132 lb 2/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious Female 132 lb 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Diverticulitis Other Serious 12/20/2009 72 Female 132 lb 3/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Atrophy Other Serious 5/1/2007 59 Female 3/17/2011 Physician Switzerland
Primary
Secondary
Dyspnoea Other Serious 12/10/2010 44 Female 228 lb 3/14/2011 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 5/1/2007 59 Female 4/11/2011 Physician Switzerland
Primary
Secondary
Cerebrovascular Accident Other Serious 59 Female 5/2/2011 Other Health Professional United States
Primary
Secondary
Inappropriate Schedule Of Drug Administration Other Serious 9/1/2008 43 Male 5/13/2011 Other Health Professional France
Primary
Secondary
C-reactive Protein Increased Hospitalization 12/14/2009 62 Female 108 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 5/24/2011 Physician France
Primary
Secondary
Hyperkeratosis Other Serious 2/1/2011 43 Male 6/8/2011 Physician France
Primary
Secondary
Infection Death 5/13/2011 67 Female 99 lb 8/4/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 8/9/2011 Other Health Professional France
Primary
Secondary
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 8/11/2011 Other Health Professional France
Primary
Secondary
Organising Pneumonia Hospitalization 3/5/2010 63 Female 117 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 6/1/2011 65 Female 8/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 4/20/2011 51 Female 154 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Folliculitis Other Serious 11/15/2008 43 Male 8/18/2011 Other Health Professional France
Primary
Secondary
Lung Neoplasm Malignant Death 3/14/2011 78 Female 8/24/2011 Physician Denmark
Primary
Secondary
Breast Cancer Stage Ii Hospitalization 8/6/2008 49 Female 115 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Death 3/14/2011 78 Female 130 lb 9/6/2011 Other Health Professional Denmark
Primary
Secondary
Lung Neoplasm Malignant Other Serious 3/14/2011 78 Female 130 lb 9/16/2011 Physician Denmark
Primary
Secondary
Cardiac Arrest Death 7/24/2011 68 Female 210 lb 9/16/2011 Consumer United States
Primary
Concomitant
Organising Pneumonia Hospitalization 3/1/2010 63 Female 117 lb 9/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperkeratosis Other Serious 2/1/2011 43 Male 10/6/2011 Physician France
Primary
Secondary
Cerebrovascular Disorder Hospitalization 9/20/2008 77 Male 98 lb 10/7/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperkeratosis Other Serious 2/1/2011 43 Male 10/14/2011 Physician France
Primary
Secondary
Cellulitis Death 5/13/2011 67 Female 99 lb 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 3/16/2011 54 Female 165 lb 10/17/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Induration 8/8/2011 62 Female 11/6/2011 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2007 49 Female 11/7/2011 Consumer United States
Primary
Concomitant
Breast Cancer Stage Ii Hospitalization 8/6/2008 49 Female 115 lb 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2011 Male 11/18/2011 Physician France
Primary
Secondary
Surgery Other Serious Female 12/14/2011 Consumer Switzerland
Primary
Concomitant
Arthralgia Other Serious 3/16/2011 54 Female 165 lb 12/14/2011 Physician Japan
Primary
Secondary
Concomitant
Surgery Other Serious Female 12/19/2011 Consumer United States
Primary
Concomitant
Diplopia Other Serious 3/1/2011 61 Male 12/19/2011 Physician France
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2011 Male 12/23/2011 Physician France
Primary
Secondary
Bladder Cancer Other Serious 3/1/2011 61 Male 12/25/2011 Physician France
Primary
Secondary
Concomitant
Infection Other Serious Female 1/2/2012 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 1/1/2008 50 Female 1/4/2012 Physician United States
Primary
Concomitant
Rash Other Serious 7 Female 1/9/2012 Physician Hungary
Primary
Secondary
Drug Ineffective Other Serious 1/1/2008 73 Female 196 lb 1/13/2012 Consumer United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 3/14/2011 78 Female 130 lb 1/18/2012 Physician Denmark
Primary
Secondary
Lung Neoplasm Malignant Death 3/14/2011 78 Female 130 lb 1/19/2012 Physician Denmark
Primary
Secondary
Rash Pustular Other Serious 7 Female 1/24/2012 Physician Hungary
Primary
Secondary
Infestation Other Serious 7 Female 1/25/2012 Physician Hungary
Primary
Secondary
Cerebrovascular Accident Male 1/26/2012 Other Health Professional United States
Primary
Concomitant
Bladder Cancer Other Serious 12/1/2004 61 Male 1/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2004 61 Male 1/30/2012 Physician France
Primary
Secondary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Retinal Vasculitis Other Serious 12/1/2004 Male 2/8/2012 Other Health Professional France
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7 Female 2/14/2012 Hungary
Primary
Secondary
Retinal Vasculitis Hospitalization 12/1/2004 54 Male 2/15/2012 Physician France
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious Female 130 lb 2/16/2012 Consumer Canada
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2008 73 Female 196 lb 2/17/2012 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 11/25/2011 75 Male 137 lb 2/21/2012 Physician Belgium
Primary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 3/7/2012 Consumer Japan
Primary
Secondary
Concomitant
Dysarthria Hospitalization 4/20/2011 51 Female 154 lb 3/22/2012 Other Health Professional United States
Primary
Concomitant
Aortic Aneurysm Rupture Life Threatening 1/22/2009 77 Female 88 lb 3/28/2012 Physician Japan
Primary
Concomitant
Genital Herpes 2/1/2012 16 Female 123 lb 4/2/2012 Physician United States
Primary
Concomitant
Injection Site Pain Other Serious 1/1/2010 23 Female 4/5/2012 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 130 lb 4/9/2012 Consumer Canada
Primary
Concomitant
Cardiac Failure Life Threatening 1/17/2009 77 Female 88 lb 4/20/2012 Japan
Primary
Concomitant
Balance Disorder Other Serious Female 148 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 1/1/2010 69 Female 4/27/2012 Physician France
Primary
Secondary
Concomitant
Surgery Other Serious Female 5/18/2012 Other Health Professional United States
Primary
Concomitant
Abortion Spontaneous Other Serious 48 Female 5/22/2012 Physician Sweden
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 11/22/2010 82 Female 75 lb 5/29/2012 Japan
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 1/1/2010 69 Female 6/11/2012 Physician France
Primary
Secondary
Concomitant
Erythema 5/15/2012 52 Female 243 lb 6/11/2012 Physician Austria
Primary
Concomitant
Gastrointestinal Disorder Other Serious Female 109 lb 6/15/2012 Physician Canada
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 25 Female 110 lb 7/2/2012 Physician France
Primary
Concomitant
Drug Ineffective 1/1/2010 70 Female 7/9/2012 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 73 Female 7/13/2012 Physician United States
Primary
Concomitant
Arthralgia Other Serious 11/18/2010 82 Female 75 lb 7/17/2012 Physician Japan
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Life Threatening 1/1/2012 78 Female 7/20/2012 Other Health Professional France
Primary
Secondary
Arthritis 16 Female 7/31/2012 Physician Mexico
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening Female 128 lb 8/3/2012 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization 47 Female 80 lb 8/20/2012 Consumer Brazil
Primary
Secondary
Concomitant
Viral Infection Other Serious 2008 48 Female 126 lb 8/16/2013 Consumer Br
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 9/2010 67 Female 12/17/2012 Other Health Professional Us
Primary
Concomitant
Weight Decreased Hospitalization Female 80 lb 10/1/2012 Physician Br
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 47 Female 80 lb 10/2/2012 Physician Br
Primary
Secondary
Concomitant
Arthralgia 8/2010 59 Male 10/24/2012 Physician Us
Primary
Concomitant
Rheumatoid Arthritis 9/2011 57 Female 10/24/2012 Physician Us
Primary
Concomitant
Urticaria Female 10/25/2012 Consumer Us
Primary
Concomitant
Nasal Disorder Other Serious Female 11/23/2012 Consumer Us
Primary
Concomitant
Weight Increased Other Serious 2012 71 Female 167 lb 6/17/2013 Physician Ca
Primary
Secondary
Concomitant
Nasal Discomfort Other Serious Female 1/2/2013 Consumer Us
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 1/29/2013 Consumer Ca
Primary
Concomitant
Nausea Hospitalization 2004 50 Male 2/21/2013 Physician Us
Primary
Concomitant
Drug Ineffective 63 Female 216 lb 8/8/2013 Physician Us
Primary
Secondary
Infection Female 3/5/2013 Consumer Us
Primary
Concomitant
Weight Increased Other Serious Female 216 lb 4/30/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Rash Pruritic 2012 62 Male 3/18/2013 Consumer Ca
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/10/2009 77 Female 3/19/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Death Female 110 lb 7/3/2013 Other Health Professional Au
Primary
Concomitant
Psoriasis Other Serious Female 4/30/2013 Physician Au
Primary
Concomitant
Rash Other Serious 4/11/2013 47 Female 168 lb 11/8/2013 Consumer Us
Primary
Concomitant
Weight Decreased Other Serious 6/22/2012 69 Male 157 lb 6/5/2013 Physician Ca
Primary
Concomitant
Vomiting Hospitalization 1/2008 22 Female 140 lb 6/4/2013 Physician Us
Primary
Concomitant
Weight Decreased Other Serious 56 Female 5/8/2013 Consumer Us
Primary
Secondary
Concomitant
Myositis 9/25/2012 69 Female 95 lb 6/11/2013 Physician Jp
Primary
Concomitant
Rheumatoid Arthritis Other Serious Male 5/10/2013 Physician Us
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious Female 167 lb 5/24/2013 Consumer Us
Primary
Concomitant
Tachycardia Other Serious 5/2/2013 53 Female 103 lb 7/22/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 3/2011 38 Female 134 lb 7/15/2013 Physician Ca
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/2008 23 Female 140 lb 5/24/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Death 64 Female 7/3/2013 Physician Us
Primary
Secondary
Concomitant
Paraesthesia 2003 44 Female 6/4/2013 Physician Us
Primary
Concomitant
Small Intestine Carcinoma Other Serious 72 Female 146 lb 10/23/2013 Consumer Br
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Death 64 Female 6/17/2013 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 6/11/2013 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 56 Female 6/14/2013 Consumer Us
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 5/2/2013 52 Female 103 lb 6/20/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Off Label Use Death 5/24/2013 61 Male 143 lb 10/2/2013 Physician Jp
Primary
Secondary
Concomitant
Pain In Extremity 2012 51 Female 7/8/2013 Physician Us
Primary
Secondary
Rheumatoid Arthritis 71 Female 7/8/2013 Physician Us
Primary
Concomitant
Wound Hospitalization 4/10/2013 64 Female 8/20/2013 Consumer Us
Primary
Secondary
Concomitant
Renal Failure Death 5/24/2013 61 Male 143 lb 9/4/2013 Physician Jp
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 62 Female 8/1/2013 Consumer Br
Primary
Secondary
Wound Other Serious 10/24/2012 83 Female 9/27/2013 Other Health Professional Us
Primary
Secondary
Concomitant
White Blood Cell Count Increased 6/2013 68 Female 8/7/2013 Physician Us
Primary
Secondary
Concomitant
Joint Swelling Hospitalization 70 Female 8/14/2013 Consumer Br
Primary
Secondary
Hypertension Hospitalization 70 Female 8/19/2013 Consumer Br
Primary
Secondary
Concomitant
Tympanic Membrane Disorder Other Serious 2013 64 Female 8/28/2013 Consumer Br
Primary
Secondary
Tinnitus Other Serious 6/2013 73 Female 142 lb 8/30/2013 Other Health Professional Us
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 58 Male 9/19/2013 Physician Il
Primary
Concomitant
Pain In Extremity 5/1/2012 63 Female 9/4/2013 Other Health Professional Us
Primary
Secondary
Drug Ineffective NotSpecified 9/10/2013 Consumer Us
Primary
Secondary
Wrist Deformity Other Serious 59 Female 9/24/2013 Physician Us
Primary
Secondary
Concomitant
Wrist Deformity Disability 59 Female 736 lb 9/27/2013 Physician Us
Primary
Secondary
Concomitant
Drug Effect Incomplete 12/2012 56 Female 179 lb 10/1/2013 Other Health Professional Us
Primary
Concomitant
Platelet Count Decreased 2003 61 Female 10/1/2013 Physician Us
Primary
Concomitant
Therapeutic Response Decreased 2000 50 Female 10/1/2013 Physician Us
Primary
Concomitant
Therapeutic Response Decreased 52 Female 10/1/2013 Physician Us
Primary
Concomitant
Drug Ineffective NotSpecified 10/1/2013 Consumer Us
Primary
Secondary
Concomitant
Injection Site Pain Male 190 lb 10/3/2013 Physician Us
Primary
Concomitant
Tendonitis 2011 48 Female 10/3/2013 Physician Us
Primary
Concomitant
Joint Swelling Hospitalization 2013 62 Female 10/11/2013 Physician Us
Primary
Secondary
Vasculitis Other Serious 7 Female 10/16/2013 Physician Hu
Primary
Secondary
Wrist Deformity Death 59 Female 11/15/2013 Consumer Us
Primary
Secondary
Concomitant
Wrist Deformity Other Serious Female 11/19/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data