Actemra combined with Aspirin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumococcal Sepsis Life Threatening 11/12/2009 Male 150 lb 1/25/2010 Physician Switzerland
Primary
Concomitant
Wrong Drug Administered Life Threatening 1/9/2010 7 Male 42 lb 3/2/2010 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/9/2010 7 Male 3/12/2010 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/8/2010 7 Male 3/15/2010 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/8/2010 7 Male 3/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/8/2010 7 Male 42 lb 3/22/2010 Physician Switzerland
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 9/29/2009 Female 154 lb 3/31/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Death 2/20/2010 50 Male 157 lb 4/5/2010 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 5/3/2006 38 Male 157 lb 4/6/2010 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 5/3/2006 38 Male 157 lb 4/23/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 10/29/2009 68 Female 151 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/1/2010 33 Female 141 lb 5/17/2010 Physician Pakistan
Primary
Concomitant
Cerebral Infarction Disability 10/29/2009 68 Female 150 lb 6/11/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 6/22/2010 63 Male 225 lb 10/12/2010 Physician Australia
Primary
Concomitant
Thyroid Neoplasm Other Serious Male 238 lb 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 5/3/2006 38 Male 157 lb 10/20/2010 Physician Japan
Primary
Concomitant
Vision Blurred Disability 4/1/2010 33 Female 141 lb 11/16/2010 Physician Pakistan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/30/2008 77 Female 11/24/2010 Physician Japan
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 9/1/2010 76 Male 181 lb 12/8/2010 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 11/18/2010 66 Female 154 lb 12/27/2010 Physician United States
Primary
Concomitant
Cardiomyopathy Other Serious 9/1/2010 76 Male 181 lb 12/28/2010 Physician Switzerland
Primary
Concomitant
Myocardial Infarction Hospitalization 6/19/2010 51 Male 287 lb 1/12/2011 Physician Russian Federation
Primary
Concomitant
Heart Rate Increased Other Serious 12/20/2010 50 Female 130 lb 1/24/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/2/2011 64 Female 182 lb 1/24/2011 Other Health Professional United States
Primary
Concomitant
Anal Ulcer Haemorrhage Hospitalization 6/30/2008 77 Female 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Anaemia Hospitalization 6/30/2008 77 Female 3/23/2011 Other Health Professional Japan
Primary
Concomitant
Bronchopneumonia Death 1/1/2010 50 Male 157 lb 4/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 3/7/2009 62 Male 274 lb 5/6/2011 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 4/1/2011 63 Female 156 lb 5/9/2011 Physician United States
Primary
Concomitant
Immunodeficiency Hospitalization 1/1/2009 67 Female 110 lb 5/13/2011 Consumer Brazil
Primary
Concomitant
Colon Cancer Hospitalization 9/14/2009 71 Male 200 lb 5/16/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 9/3/2009 60 Male 132 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Flushing Hospitalization 5/5/2011 76 Female 112 lb 5/17/2011 Physician United States
Primary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 3/16/2011 62 Male 176 lb 5/20/2011 Consumer Denmark
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 3/17/2011 80 Female 110 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/5/2011 62 Female 193 lb 6/13/2011 Other Health Professional Ireland
Primary
Concomitant
Fall Death 1/21/2011 74 Female 6/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 1/21/2011 74 Female 6/17/2011 Physician France
Primary
Secondary
Concomitant
Depression Other Serious 4/5/2011 62 Female 193 lb 6/28/2011 Other Health Professional Ireland
Primary
Concomitant
Haemorrhagic Stroke Death 1/21/2011 74 Female 7/1/2011 Physician France
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 3/1/2011 56 Male 331 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 5/5/2011 76 Female 119 lb 7/20/2011 Physician United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 7/14/2011 69 Male 174 lb 8/9/2011 Pharmacist United Kingdom
Primary
Concomitant
Phlebitis Other Serious 7/13/2011 78 Female 88 lb 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 8/1/2010 47 Male 110 lb 8/11/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 5/5/2011 56 Female 119 lb 8/12/2011 Consumer United States
Primary
Concomitant
Pupillary Reflex Impaired Hospitalization 7/14/2011 69 Male 177 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Induration 7/13/2011 78 Female 93 lb 8/26/2011 Other Health Professional Japan
Primary
Concomitant
Cardiac Arrest Death 7/24/2011 68 Female 210 lb 9/16/2011 Consumer United States
Primary
Concomitant
Arthritis Bacterial Life Threatening 4/17/2009 76 Female 10/13/2011 Japan
Primary
Secondary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 3/16/2011 62 Male 176 lb 10/18/2011 Denmark
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 2/13/2009 68 Male 108 lb 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2009 67 Female 110 lb 11/1/2011 Brazil
Primary
Concomitant
Spinal Compression Fracture Life Threatening 7/22/2010 77 Female 11/2/2011 Japan
Primary
Secondary
Concomitant
Acute Coronary Syndrome Life Threatening 1/2/2011 64 Female 162 lb 11/4/2011 Other Health Professional United States
Primary
Concomitant
Aortic Aneurysm Hospitalization 4/1/2009 78 Female 215 lb 11/10/2011 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 12/26/2010 66 Male 148 lb 11/15/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 10/28/2011 75 Female 138 lb 11/16/2011 Physician Italy
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 4/17/2009 76 Female 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 2/13/2009 68 Male 108 lb 11/21/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Death 2/6/2009 82 Male 11/23/2011 Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 7/28/2010 47 Female 11/23/2011 Japan
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 10/6/2010 66 Male 220 lb 11/23/2011 Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 11/24/2011 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 7/21/2010 65 Male 234 lb 11/24/2011 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 6/9/2009 77 Male 11/25/2011 Physician Japan
Primary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 11/25/2011 United States
Primary
Concomitant
Cardiac Failure Congestive Death 1/2/2011 64 Female 162 lb 11/29/2011 Physician United States
Primary
Concomitant
Vascular Graft Hospitalization 11/14/2011 71 Male 198 lb 11/30/2011 Canada
Primary
Concomitant
Renal Impairment Other Serious Male 12/15/2011 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 12/1/2011 55 Male 165 lb 12/19/2011 Consumer Canada
Primary
Concomitant
Spinal Compression Fracture Life Threatening 7/22/2010 77 Female 12/19/2011 Japan
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2009 56 Female 143 lb 12/19/2011 Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/28/2010 47 Female 12/19/2011 Physician Japan
Primary
Secondary
Concomitant
Sciatica Hospitalization 7/1/2011 54 Male 12/19/2011 Consumer Canada
Primary
Concomitant
Arthritis Bacterial Life Threatening 4/17/2009 76 Female 12/20/2011 Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 10/18/2011 75 Female 138 lb 12/20/2011 Italy
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 10/18/2011 75 Female 138 lb 12/21/2011 Italy
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2009 56 Female 143 lb 12/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Bronchopneumonia Other Serious 10/18/2011 75 Female 138 lb 12/23/2011 Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 11/12/2011 79 Male 121 lb 12/28/2011 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 6/9/2010 64 Female 128 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 11/24/2011 Female 110 lb 12/30/2011 Physician France
Primary
Concomitant
Death Death 1/1/2011 80 Male 1/2/2012 Japan
Primary
Concomitant
Renal Failure Other Serious 11/24/2011 Female 110 lb 1/2/2012 Physician France
Primary
Concomitant
Drug Specific Antibody Present 9/8/2011 70 Female 1/3/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 6/13/2009 74 Female 1/3/2012 Japan
Primary
Secondary
Concomitant
Bronchopneumonia Life Threatening 10/18/2011 75 Female 138 lb 1/13/2012 Italy
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 12/1/2011 55 Male 165 lb 1/13/2012 Canada
Primary
Concomitant
Pulmonary Fibrosis Other Serious 1/10/2012 69 Male 150 lb 1/17/2012 Consumer Canada
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 56 Female 143 lb 1/18/2012 Physician Brazil
Primary
Secondary
Concomitant
Metastatic Neoplasm Death 2/24/2011 70 Female 209 lb 1/18/2012 Physician Canada
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 10/18/2011 75 Female 138 lb 2/2/2012 Physician Italy
Primary
Secondary
Concomitant
Aortic Aneurysm Hospitalization 4/1/2009 78 Female 215 lb 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious Male 2/3/2012 Canada
Primary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Peripheral Revascularisation Hospitalization 11/14/2011 71 Male 198 lb 2/6/2012 Consumer Canada
Primary
Concomitant
Aortic Aneurysm Hospitalization 4/1/2009 78 Female 215 lb 2/7/2012 United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 12/1/2011 55 Male 165 lb 2/7/2012 Canada
Primary
Concomitant
Atrial Fibrillation Other Serious Male 2/9/2012 Consumer Canada
Primary
Concomitant
Pleurisy Life Threatening 12/24/2011 69 Female 2/10/2012 Physician Japan
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 2/10/2012 Consumer Israel
Primary
Concomitant
Aortic Aneurysm Hospitalization 4/1/2009 78 Female 215 lb 2/14/2012 Physician United States
Primary
Secondary
Concomitant
Dermatitis Other Serious Female 176 lb 2/14/2012 Consumer United States
Primary
Concomitant
Ulcerative Keratitis Other Serious Female 176 lb 2/15/2012 Consumer United States
Primary
Concomitant
Leukopenia Other Serious 3/16/2011 62 Male 176 lb 2/20/2012 Denmark
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 11/23/2011 78 Male 2/20/2012 Physician Japan
Primary
Concomitant
Skin Reaction Other Serious Male 198 lb 2/20/2012 Consumer Canada
Primary
Concomitant
Arthralgia Other Serious 11/25/2011 75 Male 137 lb 2/21/2012 Physician Belgium
Primary
Concomitant
Arthropathy Hospitalization 12/9/2011 49 Male 205 lb 2/24/2012 Consumer Canada
Primary
Concomitant
Death Death 10/13/2010 80 Male 2/28/2012 Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 1/10/2012 69 Male 150 lb 3/1/2012 Canada
Primary
Secondary
Concomitant
Aortic Aneurysm Hospitalization 4/1/2009 78 Female 215 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 2/28/2012 75 Male 159 lb 3/5/2012 Physician Germany
Primary
Concomitant
Anaemia Life Threatening 1/6/2012 76 Female 84 lb 3/7/2012 Consumer Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/24/2011 77 Female 3/13/2012 Japan
Primary
Secondary
Concomitant
Lung Disorder Other Serious Male 212 lb 3/14/2012 Canada
Primary
Concomitant
Interstitial Lung Disease Death 11/23/2011 78 Male 3/14/2012 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 1/10/2012 69 Male 150 lb 3/14/2012 Physician Canada
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 6/9/2009 77 Male 3/15/2012 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/25/2010 50 Female 151 lb 3/15/2012 Brazil
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2011 76 Female 123 lb 3/16/2012 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/17/2012 63 Female 3/19/2012 Physician Sweden
Primary
Concomitant
Foot Amputation Hospitalization Male 3/20/2012 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/10/2011 51 Female 4/5/2012 Physician Spain
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/18/2011 70 Male 274 lb 4/5/2012 Physician United States
Primary
Concomitant
Factor Xiii Deficiency Hospitalization 2/14/2012 70 Male 4/9/2012 Physician Austria
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 67 Female 4/11/2012 Israel
Primary
Concomitant
Myocardial Infarction Hospitalization 2/17/2012 63 Female 4/11/2012 Physician Sweden
Primary
Concomitant
Aortic Aneurysm Other Serious Male 132 lb 4/17/2012 Consumer Canada
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 1/25/2010 67 Female 115 lb 4/17/2012 Brazil
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death Male 212 lb 4/20/2012 Consumer Canada
Primary
Concomitant
Angina Pectoris Death 11/7/2011 59 Male 225 lb 4/20/2012 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2012 74 Male 110 lb 4/24/2012 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 4/18/2011 70 Male 274 lb 4/25/2012 Physician United States
Primary
Concomitant
Empyema Death Male 212 lb 4/26/2012 Consumer Canada
Primary
Concomitant
Bronchopneumopathy Other Serious 12/16/2006 79 Male 196 lb 4/26/2012 France
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 4/18/2011 70 Male 281 lb 4/30/2012 Physician United States
Primary
Secondary
Concomitant
Erythema Hospitalization 10/12/2008 49 Male 5/2/2012 Physician Japan
Primary
Concomitant
Neutrophil Count Increased Other Serious 7/28/2010 47 Female 5/3/2012 Japan
Primary
Secondary
Concomitant
Pain Hospitalization 4/5/2012 61 Male 209 lb 5/4/2012 Consumer Canada
Primary
Concomitant
Pleural Effusion Hospitalization 4/1/2012 60 Male 180 lb 5/8/2012 Physician Canada
Primary
Concomitant
Gastric Ulcer Life Threatening 1/10/2012 83 Male 185 lb 5/9/2012 Physician Germany
Primary
Concomitant
Angina Pectoris Other Serious 11/7/2011 59 Male 225 lb 5/10/2012 Physician United States
Primary
Concomitant
Atrial Fibrillation Death 4/18/2011 70 Male 274 lb 5/10/2012 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 3/18/2012 67 Female 150 lb 5/10/2012 Physician Israel
Primary
Concomitant
Cardiopulmonary Failure Death 4/18/2011 70 Male 274 lb 5/11/2012 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 8/28/2011 69 Male 196 lb 5/11/2012 Germany
Primary
Concomitant
Death Death 4/24/2012 58 Male 165 lb 5/11/2012 Canada
Primary
Concomitant
Urosepsis Hospitalization 2/6/2009 82 Male 5/24/2012 Physician Japan
Primary
Concomitant

Drug Data