Actemra combined with Arava

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Acute Hospitalization 7/24/2009 Female 121 lb 1/15/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 8/1/2009 Male 154 lb 2/8/2010 Physician Brazil
Primary
Secondary
Concomitant
Rash Vesicular Other Serious 9/29/2009 Female 154 lb 3/31/2010 Physician Germany
Primary
Concomitant
Epistaxis Other Serious Female 5/28/2010 Other Health Professional Australia
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 123 lb 6/1/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 123 lb 6/21/2010 Physician United States
Primary
Concomitant
Epistaxis Other Serious 4/1/2010 47 Female 165 lb 6/25/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 6/28/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Extremity Necrosis Hospitalization 5/22/2010 53 Female 150 lb 7/8/2010 Physician Switzerland
Primary
Concomitant
Psychotic Disorder Hospitalization 5/1/2010 25 Female 88 lb 7/14/2010 Physician Switzerland
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 7/28/2010 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 6/21/2010 56 Male 170 lb 8/18/2010 Physician United States
Primary
Concomitant
Headache Other Serious 7/20/2010 69 Female 188 lb 8/27/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 7/1/2010 44 Female 10/19/2010 Physician Russian Federation
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/30/2010 62 Female 157 lb 11/10/2010 Consumer Switzerland
Primary
Concomitant
Alopecia Other Serious 5/1/2010 41 Female 112 lb 11/11/2010 Physician United States
Primary
Secondary
Alopecia 5/1/2010 41 Female 112 lb 11/17/2010 Physician United States
Primary
Secondary
Interstitial Lung Disease Hospitalization 1/4/2011 72 Male 132 lb 1/31/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/4/2011 72 Male 132 lb 2/10/2011 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 72 Male 4/6/2011 Physician Japan
Primary
Secondary
Cardiac Arrest Death 8/30/2009 59 Female 267 lb 5/6/2011 Physician United States
Primary
Concomitant
Acute Respiratory Failure Death 4/22/2011 57 Female 128 lb 5/9/2011 Physician United States
Primary
Secondary
Joint Effusion Hospitalization 2/4/2011 69 Female 5/12/2011 Physician Switzerland
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 9/1/2008 43 Male 5/13/2011 Other Health Professional France
Primary
Secondary
Renal Failure Acute Other Serious 4/22/2011 57 Female 128 lb 5/16/2011 Physician United States
Primary
Secondary
Concomitant
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 5/24/2011 Physician France
Primary
Secondary
Tuberculosis Hospitalization 1/1/2011 46 Male 78 lb 5/27/2011 Consumer Spain
Primary
Concomitant
Palatitis Hospitalization Female 5/31/2011 Physician Japan
Primary
Concomitant
Oedema Other Serious 2/1/2011 51 Female 289 lb 6/3/2011 Physician France
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/1/2011 59 Female 185 lb 6/3/2011 Consumer Australia
Primary
Concomitant
Anaemia Hospitalization 48 Male 6/8/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hyperkeratosis Other Serious 2/1/2011 43 Male 6/8/2011 Physician France
Primary
Secondary
Dermatitis Psoriasiform Other Serious 43 Male 6/15/2011 Other Health Professional France
Primary
Secondary
Fall Death 1/21/2011 74 Female 6/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 1/21/2011 74 Female 6/17/2011 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/1/2011 59 Female 185 lb 6/29/2011 Physician Australia
Primary
Concomitant
Haemorrhagic Stroke Death 1/21/2011 74 Female 7/1/2011 Physician France
Primary
Secondary
Concomitant
Epiglottitis Life Threatening 2/19/2011 71 Female 110 lb 7/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious Female 7/27/2011 Other Health Professional Sweden
Primary
Concomitant
Dyspnoea Hospitalization 5/2/2011 74 Female 146 lb 8/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 8/9/2011 Other Health Professional France
Primary
Secondary
Dermatitis Psoriasiform Other Serious 11/15/2008 43 Male 8/11/2011 Other Health Professional France
Primary
Secondary
Small Cell Lung Cancer Stage Unspecified Hospitalization 6/1/2011 65 Female 8/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Folliculitis Other Serious 11/15/2008 43 Male 8/18/2011 Other Health Professional France
Primary
Secondary
Skin Reaction Hospitalization Female 8/31/2011 Consumer Germany
Primary
Concomitant
Hyperkeratosis Other Serious 2/1/2011 43 Male 10/6/2011 Physician France
Primary
Secondary
Hyperkeratosis Other Serious 2/1/2011 43 Male 10/14/2011 Physician France
Primary
Secondary
Renal Tubular Disorder Other Serious 6/1/2009 44 Female 193 lb 10/17/2011 Physician Switzerland
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 9/1/2009 53 Female 154 lb 10/20/2011 Consumer Brazil
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 6/1/2009 43 Female 193 lb 10/21/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Chest Discomfort Other Serious Female 10/21/2011 Other Health Professional Australia
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 8/5/2011 71 Female 10/28/2011 Physician France
Primary
Concomitant
Arthroscopy Hospitalization Male 10/28/2011 Physician Australia
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/29/2011 56 Female 11/1/2011 Consumer Australia
Primary
Concomitant
Coma Life Threatening 9/29/2011 56 Female 154 lb 11/8/2011 Consumer Australia
Primary
Concomitant
Kidney Infection Hospitalization 7/10/2011 66 Female 123 lb 11/15/2011 Other Health Professional Canada
Primary
Concomitant
Rash Hospitalization Male 143 lb 12/5/2011 Physician Finland
Primary
Secondary
Concomitant
Ankle Arthroplasty Hospitalization 8/24/2011 49 Female 130 lb 12/13/2011 Consumer Canada
Primary
Concomitant
Unevaluable Event Hospitalization 1/1/2010 72 Male 152 lb 12/14/2011 Physician Germany
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2009 56 Female 143 lb 12/19/2011 Brazil
Primary
Secondary
Concomitant
Diplopia Other Serious 3/1/2011 61 Male 12/19/2011 Physician France
Primary
Secondary
Concomitant
Rash Hospitalization Male 143 lb 12/21/2011 Finland
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2009 56 Female 143 lb 12/22/2011 Physician Brazil
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 3/1/2011 61 Male 12/25/2011 Physician France
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization Male 12/27/2011 France
Primary
Concomitant
Head Injury Other Serious Female 156 lb 1/2/2012 Consumer United States
Primary
Concomitant
Femur Fracture Hospitalization 1/27/2011 80 Male 1/11/2012 Physician France
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/27/2011 80 Male 1/12/2012 Physician France
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 11/15/2011 60 Male 187 lb 1/13/2012 Physician Germany
Primary
Concomitant
Femur Fracture Hospitalization 4/3/2011 80 Male 1/13/2012 Physician France
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 4/3/2011 80 Male 1/17/2012 Other Health Professional France
Primary
Secondary
Pain In Extremity Other Serious 1/1/2009 56 Female 143 lb 1/18/2012 Physician Brazil
Primary
Secondary
Concomitant
Arthroscopy Other Serious Male 1/19/2012 Physician Australia
Primary
Concomitant
Skin Necrosis Hospitalization 5/1/2010 53 Female 185 lb 1/26/2012 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/25/2010 50 Female 148 lb 1/27/2012 Brazil
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 12/1/2004 61 Male 1/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2004 61 Male 1/30/2012 Physician France
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2010 72 Male 152 lb 2/2/2012 Physician Germany
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization Female 2/6/2012 Physician Switzerland
Primary
Concomitant
Retinal Vasculitis Other Serious 12/1/2004 Male 2/8/2012 Other Health Professional France
Primary
Secondary
Concomitant
Retinal Vasculitis Hospitalization 12/1/2004 54 Male 2/15/2012 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 11/6/2011 Female 2/15/2012 Physician Germany
Primary
Concomitant
Bladder Cancer Other Serious 3/1/2011 54 Male 2/17/2012 Physician France
Primary
Secondary
Concomitant
Klebsiella Infection Hospitalization 5/1/2010 53 Female 185 lb 2/21/2012 Germany
Primary
Secondary
Concomitant
Cellulitis Other Serious Female 2/23/2012 Physician Switzerland
Primary
Concomitant
Anhedonia Life Threatening 8/1/2011 61 Female 225 lb 2/28/2012 Physician Australia
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Death 2/8/2012 76 Female 176 lb 3/1/2012 Physician Australia
Primary
Secondary
Concomitant
Adverse Drug Reaction Other Serious Female 3/5/2012 Australia
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 10/15/2009 39 Male 165 lb 3/6/2012 Physician Belgium
Primary
Secondary
Concomitant
Eosinophilia 1/19/2012 19 Female 3/7/2012 Physician Finland
Primary
Concomitant
Paraesthesia Other Serious 11/17/2009 39 Female 148 lb 3/7/2012 Consumer Brazil
Primary
Concomitant
Interacting
Aortic Aneurysm Rupture Death 2/8/2012 76 Female 176 lb 3/9/2012 Physician Australia
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 2/1/2012 49 Female 110 lb 3/12/2012 Consumer Canada
Primary
Concomitant
Intraocular Pressure Increased Other Serious 2/1/2012 49 Female 110 lb 3/13/2012 Consumer Canada
Primary
Concomitant
Intraocular Pressure Increased Other Serious 2/1/2012 49 Female 110 lb 3/14/2012 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 6/25/2010 50 Female 151 lb 3/15/2012 Brazil
Primary
Secondary
Concomitant
Nightmare Other Serious 1/1/2011 50 Female 180 lb 4/3/2012 Consumer Canada
Primary
Concomitant
Intraocular Pressure Increased Other Serious 2/1/2012 49 Female 110 lb 4/6/2012 Canada
Primary
Concomitant
Nightmare Other Serious 1/1/2011 50 Female 180 lb 4/13/2012 Canada
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 1/1/2011 50 Female 180 lb 4/16/2012 Physician Canada
Primary
Concomitant
Diarrhoea Hospitalization 7/10/2011 66 Female 134 lb 4/20/2012 Other Health Professional Canada
Primary
Concomitant
Ulcer Haemorrhage Hospitalization Male 275 lb 4/20/2012 Consumer Canada
Primary
Concomitant
Balance Disorder Other Serious Female 148 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/27/2012 63 Male 183 lb 4/24/2012 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 2/1/2012 49 Female 110 lb 4/26/2012 Consumer Canada
Primary
Concomitant
Hyperglycaemia Hospitalization Male 275 lb 4/26/2012 Consumer Canada
Primary
Concomitant
Pain Other Serious 11/17/2009 39 Female 148 lb 5/3/2012 Consumer Brazil
Primary
Concomitant
Interacting
Blood Urine Present Other Serious Male 229 lb 5/8/2012 Consumer Canada
Primary
Concomitant
Pancytopenia Hospitalization 10/26/2011 55 Female 123 lb 5/17/2012 Physician Spain
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/1/2012 25 Male 143 lb 5/17/2012 Canada
Primary
Concomitant
Addison's Disease Hospitalization 9/19/2011 28 Female 117 lb 5/18/2012 Physician United Kingdom
Primary
Concomitant
Back Pain Hospitalization 11/8/2011 57 Female 190 lb 5/22/2012 Consumer United Kingdom
Primary
Concomitant
Pain Hospitalization 1/4/2012 47 Female 128 lb 5/24/2012 Consumer Brazil
Primary
Concomitant
Pulmonary Oedema Hospitalization 5/14/2012 70 Female 148 lb 5/24/2012 Consumer Canada
Primary
Concomitant
Arthralgia Other Serious Female 5/24/2012 Other Health Professional Australia
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 56 Female 143 lb 5/24/2012 Physician Brazil
Primary
Secondary
Concomitant
Testicular Necrosis Hospitalization 4/26/2012 25 Male 143 lb 6/4/2012 Consumer Canada
Primary
Concomitant
Acute Respiratory Failure Hospitalization 28 6/7/2012 Physician United States
Primary
Concomitant
Phlebitis Hospitalization Female 6/8/2012 Consumer United States
Primary
Concomitant
Erythema 5/15/2012 52 Female 243 lb 6/11/2012 Physician Austria
Primary
Concomitant
Periodontitis Hospitalization 8/19/2008 41 Female 6/14/2012 Japan
Primary
Secondary
Concomitant
Throat Irritation Other Serious 3/21/2012 53 Female 1105 lb 6/15/2012 Other Health Professional United States
Primary
Concomitant
Death Death 7/10/2011 66 Female 134 lb 7/6/2012 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization Female 7/12/2012 Physician United States
Primary
Concomitant
Fall Hospitalization 1/1/2010 48 Female 128 lb 7/18/2012 Consumer Brazil
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 7/1/2012 75 Female 140 lb 7/24/2012 Consumer Canada
Primary
Concomitant
Extremity Necrosis Other Serious 1/2/2012 66 Female 132 lb 7/26/2012 Physician Finland
Primary
Concomitant
Blood Pressure Increased Other Serious 12/9/2010 42 Female 245 lb 7/31/2012 Physician Canada
Primary
Secondary
Concomitant
Nasal Congestion Other Serious 12/9/2010 42 Female 245 lb 8/3/2012 Physician Canada
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening Female 128 lb 8/3/2012 Consumer Brazil
Primary
Concomitant
Encephalitis Other Serious Female 148 lb 8/6/2012 Physician South Africa
Primary
Concomitant
Cough Hospitalization 1/1/2010 72 Male 152 lb 8/10/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 5/1/2012 69 Female 160 lb 8/22/2012 Consumer Canada
Primary
Concomitant
Spinal Fracture Hospitalization 7/2012 Female 143 lb 2/14/2013 Physician Ca
Primary
Concomitant
Death Death Male 10/17/2012 Physician Us
Primary
Concomitant
Menorrhagia Other Serious 3/2012 Female 185 lb 1/29/2013 Consumer Ca
Primary
Concomitant
Tendon Rupture Other Serious 7/2012 Female 161 lb 10/12/2012 Physician Us
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 12/11/2012 Consumer Us
Primary
Concomitant
Rash Erythematous Other Serious 12/20/2012 59 Female 2/6/2013 Consumer Au
Primary
Concomitant
Pain In Jaw Hospitalization 12/4/2012 59 Male 154 lb 1/25/2013 Physician Au
Primary
Concomitant
Septic Shock Hospitalization 1/15/2013 Male 1/23/2013 Other Health Professional Us
Primary
Concomitant
Gallbladder Polyp Other Serious 11/2012 Female 126 lb 1/22/2013 Consumer Ca
Primary
Concomitant
Sciatica Other Serious 6/2012 Female 120 lb 1/25/2013 Other Health Professional Ca
Primary
Concomitant
Throat Tightness Other Serious 1/22/2013 48 Female 192 lb 1/28/2013 Other Health Professional Ca
Primary
Concomitant
Ligament Rupture Other Serious 1/9/2013 Male 1/29/2013 Other Health Professional Au
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/28/2013 77 Male 3/14/2013 Physician Au
Primary
Concomitant
Pustular Psoriasis Other Serious Male 300 lb 2/11/2013 Physician Ae
Primary
Concomitant
Ligament Rupture Other Serious 1/9/2013 57 Male 2/25/2013 Consumer Au
Primary
Secondary
Paraesthesia Other Serious 3/2/2013 64 Female 3/7/2013 Other Health Professional Au
Primary
Concomitant

Drug Data