Acetylsalicylic Acid combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastrointestinal Haemorrhage Life Threatening 1/3/2006 81 Male 176 lb 1/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/6/2002 89 Female 141 lb 1/26/2006 United Kingdom
Primary
Concomitant
Sensory Loss Hospitalization 11/2/2005 Male 1/26/2006 Italy
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/26/2006 64 Male 205 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Haematuria Hospitalization 9/2/2006 86 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2004 61 Male 10/1/2007 Lawyer Brazil
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/2/2007 Female 10/8/2007 United States
Primary
Concomitant
Malaise Other Serious Female 189 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 8/28/2007 60 Male 220 lb 10/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Congestion 1/17/2008 Female 3/15/2008 United States
Primary
Concomitant
Rash 1/1/2008 Female 3/15/2008 Other Health Professional United States
Primary
Concomitant
Renal Mass Hospitalization 2/15/2008 Male 228 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 2/20/2008 62 Female 3/19/2008 Sweden
Primary
Concomitant
Coronary Artery Disease Hospitalization 7/29/2008 Male 183 lb 12/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 8/1/2006 Male 12/17/2008 United States
Primary
Concomitant
Splenomegaly Other Serious 1/20/2008 12/22/2008 Other Health Professional Singapore
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 12/23/2008 Physician Spain
Primary
Concomitant
Renal Failure Other Serious 1/1/1998 78 Male 137 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 1/28/2009 Physician Spain
Primary
Concomitant
Myocardial Infarction Other Serious 9/27/2006 48 Male 110 lb 2/19/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 362 lb 3/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2008 43 Female 362 lb 3/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 5/22/2008 50 Male 3/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 3/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspepsia Hospitalization 10/10/2008 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/9/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/11/2009
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/13/2008 44 Male 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/30/2009 86 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Road Traffic Accident Hospitalization 5/10/2008 Female 176 lb 3/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 44 Female 3/20/2009 United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 10/25/2007 Female 167 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/6/2007 Female 151 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 3/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/30/2009 86 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 7/29/2007 80 Male 4/8/2009 Other Health Professional France
Primary
Concomitant
Interacting
Pemphigoid Other Serious 74 5/12/2009 Physician Greece
Primary
Secondary
Bronchitis Hospitalization 3/29/2007 77 5/25/2009 Physician Poland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 68 6/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Palpitations Hospitalization 5/26/2009 69 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/3/2003 Male 139 lb 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2002 47 Female 255 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/24/2009 Physician Spain
Primary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/1/2009 78 9/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hyperkalaemia Other Serious 9/1/2009 78 Male 9/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/30/2009 61 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Vascular Graft Thrombosis Hospitalization 10/19/2009 Female 133 lb 11/23/2009 Physician Greece
Primary
Concomitant
Violence-related Symptom Other Serious 10/3/2009 79 Male 11/18/2009 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 5/1/2007 43 Female 360 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 10/10/2008 43 Female 11/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 4/1/2008 80 Female 12/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 56 Male 1/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sputum Discoloured Other Serious 56 Male 1/8/2010 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 11/1/2008 77 Male 260 lb 12/10/2009 United States
Primary
Concomitant
Wound Complication Other Serious 5/1/2009 Female 108 lb 1/20/2010 Brazil
Primary
Concomitant
Paraesthesia Oral Hospitalization 57 Male 1/26/2010 Norway
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 Male 206 lb 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 73 Male 152 lb 2/10/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 1/16/2010 75 Female 2/12/2010 Physician Denmark
Primary
Concomitant
Transaminases Increased Hospitalization 6/11/2009 74 Female 132 lb 3/12/2010 Spain
Primary
Concomitant
Myocardial Infarction Other Serious 1/20/2010 Male 206 lb 3/23/2010 Consumer United States
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 69 Male 206 lb 4/13/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 5/1/2009 76 Female 108 lb 4/22/2010 Brazil
Primary
Concomitant
Vomiting Hospitalization 2/13/2010 72 Female 176 lb 4/27/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/27/2010 72 Female 176 lb 5/5/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious Male 159 lb 5/6/2010 Physician United States
Primary
Concomitant
Tremor Life Threatening 1/9/2010 70 Female 5/10/2010 Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2010 72 Female 176 lb 5/18/2010 Physician United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 5/18/2010 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 1/21/2010 71 Male 224 lb 5/19/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/9/2010 70 Female 5/21/2010 Physician Netherlands
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/31/2009 44 Female 117 lb 6/10/2010 Consumer Brazil
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 4/13/2010 63 Male 154 lb 6/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 9/11/2009 81 Female 6/29/2010 Physician United Kingdom
Primary
Concomitant
Tongue Discolouration Hospitalization 5/3/2010 74 Female 121 lb 6/30/2010 Consumer United States
Primary
Concomitant
Tobacco User 10/1/2006 53 Male 178 lb 7/8/2010 Consumer United States
Primary
Concomitant
Flatulence 2/1/2007 66 Male 148 lb 7/9/2010 Consumer United States
Primary
Concomitant
Tremor 3/8/2007 80 Female 153 lb 7/12/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 3/15/2007 75 Male 210 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 5/1/2007 64 Female 137 lb 7/13/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 4/25/2007 57 Female 145 lb 7/13/2010 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal 2/20/2007 76 Female 101 lb 7/14/2010 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/28/2007 56 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Other Serious 9/1/2007 67 Male 7/15/2010 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased 10/19/2007 45 Male 216 lb 7/16/2010 Consumer United States
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 3/17/2010 41 Male 273 lb 7/21/2010 Physician Denmark
Primary
Concomitant
Sleep Disorder 12/1/2007 54 Male 190 lb 7/21/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2010 64 Male 300 lb 8/16/2010 Consumer United States
Primary
Concomitant
Myalgia Other Serious 1/1/2003 32 Male 185 lb 8/19/2010 Consumer United States
Primary
Concomitant
Medication Residue 1/1/2010 60 Male 293 lb 8/20/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 6/23/2009 70 Male 165 lb 8/30/2010 Physician
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 3/29/2010 71 Male 9/8/2010 Other Health Professional Japan
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 12/1/2009 75 Male 149 lb 9/9/2010 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/6/2010 70 Female 9/9/2010 Physician Russian Federation
Primary
Concomitant
Vision Blurred Other Serious 1/1/2010 67 Male 172 lb 9/10/2010 Consumer Brazil
Primary
Concomitant
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 9/13/2010 Physician United States
Primary
Concomitant
Interacting
Renal Impairment Hospitalization 6/23/2009 70 Male 165 lb 9/13/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 9/22/2010 Physician United States
Primary
Secondary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 11/1/2007 73 Male 152 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Renal Impairment Hospitalization 6/23/2009 70 Male 165 lb 9/23/2010 Consumer United States
Primary
Secondary
Concomitant
Exfoliative Rash Other Serious 85 Female 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 85 Female 9/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Bradycardia Life Threatening 4/13/2010 63 Male 154 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Chills Other Serious 71 Female 10/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Anxiety 9/28/2010 65 Male 160 lb 10/7/2010 Consumer United States
Primary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 10/19/2010 Physician Netherlands
Primary
Secondary
Concomitant
Interacting
Nausea 1/1/2010 64 Female 148 lb 10/28/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2010 67 Male 172 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Vertigo Other Serious 9/28/2010 65 Male 160 lb 11/3/2010 Consumer United States
Primary
Concomitant
Malaise Other Serious 6/23/2009 70 Male 165 lb 10/27/2010 Physician
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/23/2009 70 Male 165 lb 11/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Interacting
Glycosylated Haemoglobin Increased Other Serious 63 Male 190 lb 11/23/2010 Physician United Kingdom
Primary
Concomitant
Troponin Increased Hospitalization 11/9/2010 70 Male 11/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Abnormal Dreams Other Serious 69 Male 11/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Disability 1/1/2010 87 Female 119 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 71 Female 117 lb 12/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Troponin Increased Hospitalization 11/9/2010 70 Male 12/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 11/11/2010 Male 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/1/2010 85 Male 1/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2010 87 Female 119 lb 1/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Duodenal Scarring Other Serious 61 Male 2/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Device Malfunction Disability 12/1/2009 75 Male 150 lb 2/9/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Depression Other Serious 9/10/2008 54 Male 2/10/2011 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/26/2011 74 Male 187 lb 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Eye Pruritus Other Serious 12/4/2008 67 Male 254 lb 2/17/2011 Other Health Professional United States
Primary
Concomitant
Myopathy Hospitalization 2/3/2011 69 Male 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chest Discomfort Life Threatening 1/11/2011 76 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Life Threatening 1/26/2011 74 Male 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/1/2010 80 Female 106 lb 3/13/2011 Consumer Netherlands
Primary
Concomitant
Diarrhoea Hospitalization 1/13/2011 76 Male 3/9/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pruritus Other Serious 2/1/2011 64 Male 174 lb 3/30/2011 Physician Greece
Primary
Concomitant
Vomiting Hospitalization 1/11/2011 76 Male 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Hospitalization 6/23/2009 70 Male 165 lb 4/15/2011 Physician Netherlands
Primary
Secondary
Concomitant
Malaise Hospitalization 6/23/2009 70 Male 165 lb 4/19/2011 Physician Netherlands
Primary
Secondary
Concomitant
Dyspnoea Other Serious 4/9/2011 64 Female 132 lb 5/10/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data