Acetylcysteine combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Eosinophilia Hospitalization 11/17/2005 Male 2/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/17/2006 34 Female 110 lb 2/8/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Injection Site Haemorrhage Required Intervention 9/23/2005 42 Female 183 lb 2/28/2006 United States
Primary
Secondary
Concomitant
Post Procedural Complication Disability 5/12/2006 85 Female 112 lb 5/24/2006 United States
Primary
Concomitant
Respiratory Depression Life Threatening 2/25/2005 44 Female 7/24/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 80 Female 130 lb 5/9/2005 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 79 Male 196 lb 5/9/2005 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/8/2005 Male 168 lb 10/2/2006 Physician United States
Primary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/16/2006 Physician Germany
Primary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/19/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 9/18/2006 69 Male 198 lb 10/23/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 10/27/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 11/1/2006 Physician Germany
Primary
Concomitant
Death Death 10/6/2006 74 Male 10/17/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/3/2006 Physician Germany
Primary
Concomitant
Lymphadenopathy Other Serious 6/1/2006 44 Male 11/7/2006 Physician France
Primary
Secondary
Concomitant
Rash Other Serious 5/29/2006 48 Male 11/8/2006 Pharmacist Canada
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/15/2006 Physician Germany
Primary
Concomitant
Kaposi's Sarcoma Other Serious 6/1/2006 44 Male 11/17/2006 Physician France
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/27/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 10/8/2005 Male 168 lb 11/28/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 12/4/2006 Physician Germany
Primary
Concomitant
Shock Haemorrhagic Life Threatening 6/16/2006 74 Female 11/27/2006 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 11/27/2006 France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 8/20/2006 35 Male 176 lb 12/11/2006 Physician Canada
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 8/15/2006 Male 243 lb 8/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 1/12/2007 Physician Germany
Primary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/1/2007 Physician France
Primary
Secondary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/5/2007 Physician France
Primary
Secondary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 2/5/2007 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/27/2006 67 Male 196 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 2/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 2/15/2007 Other Health Professional France
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 3/13/2007 Physician Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/31/2007 57 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Septic Shock Life Threatening 10/20/2005 34 Male 4/3/2007 Physician France
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/1/2007 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/11/2007 Physician Germany
Primary
Concomitant
Human Herpesvirus 8 Infection Other Serious 6/1/2006 44 Male 5/17/2007 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/1/2006 69 Male 198 lb 5/22/2007 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 44 Male 5/24/2007 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 170 lb 6/21/2007 Physician Germany
Primary
Concomitant
Sepsis Other Serious 71 Female 170 lb 7/5/2007 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 2/10/2007 87 Female 176 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 80 Female 194 lb 1/31/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/21/2005 63 Male 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/22/2007 Female 194 lb 2/28/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/21/2005 3/5/2008 Other Health Professional United States
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 7/21/2005 62 Male 3/8/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/21/2005 3/19/2008 Other Health Professional United States
Primary
Secondary
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Suicide Attempt Other Serious 78 Male 134 lb 8/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/4/1999 Female 150 lb 7/23/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 12/1/2008 Physician United States
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/8/2008 82 Male 146 lb 11/21/2008 United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 12/8/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 12/8/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 12/16/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 2/3/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Moniliasis Life Threatening 11/4/2008 Male 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Hospitalization 2/24/2009 50 Male 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Hospitalization 2/24/2009 50 Male 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/5/2009 Female 6/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Liver Injury Other Serious 6/17/2009 0 Female 19 lb 7/7/2009 Pharmacist United States
Primary
Concomitant
Ureteric Stenosis Required Intervention 7/10/2003 69 Male 8/13/2009 Physician Germany
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 11/8/2008 82 Male 146 lb 9/24/2009 United States
Primary
Secondary
Concomitant
Death Death 10/2/2009 Physician Korea, Republic Of
Primary
Concomitant
Aspergillosis Death 11/1/2007 39 10/12/2009 Physician Korea, Republic Of
Primary
Concomitant
Haematoma Other Serious 11/19/2009 25 Male 193 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
Renal Impairment Death 2/25/2009 87 Female 106 lb 1/6/2010 Physician Japan
Primary
Concomitant
Wound Secretion Hospitalization 11/16/2009 75 Male 161 lb 1/26/2010 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 11/16/2009 75 Male 161 lb 2/1/2010 Physician Germany
Primary
Concomitant
Embolism Hospitalization 12/31/2008 70 Male 220 lb 2/2/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/16/2009 75 Male 161 lb 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/7/2008 Male 2/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/4/2007 76 Female 2/25/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 3/22/2010 Physician Germany
Primary
Secondary
Concomitant
Hypotension Death 10/1/2009 66 Male 152 lb 2/24/2010 Pharmacist United States
Primary
Concomitant
Rash Required Intervention 12/8/2009 58 Female 101 lb 12/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Post Procedural Haematoma Hospitalization 4/30/2010 33 Male 131 lb 5/10/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/7/2008 58 Male 6/21/2010 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/4/2007 76 Female 6/24/2010 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/17/2007 70 Female 6/30/2010 Physician Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 11/1/2009 Male 7/6/2010 Physician Germany
Primary
Concomitant
Renal Failure Acute Life Threatening 10/22/2008 89 Female 165 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/19/2007 58 Male 8/23/2010 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/1/2010 75 Male 179 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/2/2010 86 Male 132 lb 9/22/2010 Physician Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 9/7/2010 80 Female 183 lb 9/24/2010 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 10/23/2010 59 Male 161 lb 12/6/2010 Pharmacist Germany
Primary
Concomitant
Hepatitis C Other Serious 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 1/10/2011 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/12/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 10/23/2010 59 Male 161 lb 1/25/2011 Pharmacist Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 79 Male 1/28/2011 Physician
Primary
Concomitant
Respiratory Failure Hospitalization 10/23/2010 59 Male 161 lb 2/17/2011 Other Health Professional Germany
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 10/25/2010 72 Male 159 lb 2/22/2011 Other Health Professional France
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 10/25/2010 72 Male 159 lb 3/2/2011 Other Health Professional France
Primary
Concomitant
Sepsis Life Threatening 10/22/2010 72 Male 159 lb 3/11/2011 Other Health Professional France
Primary
Concomitant
Hypoglycaemic Unconsciousness Life Threatening 3/5/2011 70 Male 162 lb 3/16/2011 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 10/22/2010 72 Male 154 lb 3/30/2011 Other Health Professional France
Primary
Concomitant
Medication Error Other Serious 10/22/2010 72 Male 154 lb 4/4/2011 Other Health Professional France
Primary
Concomitant
Fear Other Serious 2/18/2006 73 Male 239 lb 4/13/2011 Other Health Professional United States
Primary
Concomitant
Cholestasis Death 47 Male 4/14/2011 Pharmacist Germany
Primary
Concomitant
Renal Injury Other Serious 9/1/1995 72 Female 109 lb 4/21/2011 Other Health Professional United States
Primary
Concomitant
Dysstasia Hospitalization 1/1/2010 69 Male 165 lb 4/12/2011 Physician Germany
Primary
Concomitant
Agitation Death 1/1/2010 69 Male 165 lb 4/15/2011 Other Health Professional Germany
Primary
Concomitant
Renal Injury Hospitalization 11/18/2005 57 Male 139 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Adverse Event Other Serious 12/2/2005 59 Male 165 lb 5/10/2011 Other Health Professional United States
Primary
Concomitant
Deafness Unilateral Other Serious 1/1/2011 33 Female 110 lb 5/11/2011 Physician Germany
Primary
Concomitant
Flashback Other Serious 5/1/2005 62 Female 132 lb 5/20/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 8/1/2010 85 Female 165 lb 6/3/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Electrocardiogram Qt Prolonged Hospitalization 4/30/2010 33 Male 131 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Injury Other Serious 8/16/2007 75 Male 170 lb 6/25/2011 Lawyer United States
Primary
Concomitant
Pneumonia Death 12/17/2010 83 Male 172 lb 7/2/2011 Physician United States
Primary
Secondary
Concomitant
Depression Death 7/1/2005 62 Male 161 lb 7/6/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 53 Male 245 lb 7/18/2011 Other Health Professional United States
Primary
Concomitant
Lung Infiltration Other Serious 6/23/2011 74 Male 8/23/2011 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 9/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/1/2010 85 Female 165 lb 9/28/2011 Physician United States
Primary
Concomitant
Interacting
Cholestasis Death 47 Male 10/27/2011 Pharmacist Germany
Primary
Concomitant
Rash Death 53 Male Other Health Professional United States
Primary
Concomitant
Ejection Fraction Decreased Death Male Other Health Professional United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome 2 Male 11/3/2011 Other Health Professional United States
Primary
Secondary
Ileus Paralytic Life Threatening 9/1/2011 57 Male 309 lb 11/29/2011 Physician Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/1/2010 70 Male 165 lb 12/8/2011 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 12/16/2010 83 Male 172 lb 12/14/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Death 1/1/2010 70 Male 165 lb 2/28/2012 Physician Germany
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 4/30/2010 33 Male 131 lb 3/1/2012 Physician Germany
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 5/11/2012 65 Female 189 lb 6/21/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/11/2012 65 Female 189 lb 6/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Life Threatening 7/21/2005 62 Male 6/29/2012 Other Health Professional Germany
Primary
Secondary
Pruritus Life Threatening 7/21/2005 62 Male 7/3/2012 Physician Germany
Primary
Secondary
Respiratory Failure Death 75 Female 7/10/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/16/2010 83 Male 172 lb 7/12/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 12/17/2010 83 Male 172 lb 7/13/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/16/2010 83 Male 172 lb 7/30/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 64 Female 220 lb 8/23/2012 Other Health Professional United States
Primary
Concomitant
Vitamin D Decreased Other Serious Female 255 lb Lawyer Us
Primary
Concomitant
Right Ventricular Failure Death 6/2011 73 Female 9/13/2012 Physician De
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 9/3/2012 55 Female 5/6/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data