Acetylcysteine combined with Allopurinol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sudden Death Death 11/3/2005 Male 1/31/2006 Physician Poland
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/31/2002 63 Male 161 lb 3/20/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Fatigue Hospitalization 11/3/2005 Male 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/21/2006 Physician Poland
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/22/2006 83 Female 4/26/2006 Sweden
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Disorder Hospitalization 1/8/2006 80 Male 6/22/2006 Germany
Primary
Concomitant
Pulse Absent Other Serious 1/20/2006 85 Male 154 lb 6/20/2006 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Death 6/19/2006 52 Male 143 lb 7/20/2006 Physician Belgium
Primary
Concomitant
Thrombocytopenia Other Serious 80 Female 130 lb 5/9/2005 Pharmacist United States
Primary
Secondary
Concomitant
Muscle Haemorrhage Death 7/1/2006 78 Male 132 lb 10/6/2006 Physician Portugal
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/27/2007 Physician Poland
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 5/25/2007 Physician Poland
Primary
Secondary
Concomitant
Deafness Neurosensory Other Serious 6/5/2007 66 Male 6/22/2007 Physician Germany
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 7/11/2007 Physician Poland
Primary
Secondary
Concomitant
Inner Ear Disorder Other Serious 6/5/2007 66 Male 7/26/2007 Physician Germany
Primary
Concomitant
Colon Neoplasm Hospitalization 8/3/2007 77 Male 8/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tinnitus Other Serious 6/5/2007 66 Male 8/23/2007 Physician Germany
Primary
Concomitant
Tinnitus Other Serious 5/10/2007 66 Male 10/12/2007 Physician Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Death 10/22/2007 62 Male 139 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 3/17/2005 54 Female 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Seizure Anoxic Hospitalization 12/4/2007 87 Male 3/18/2008 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Hospitalization 1/7/2008 83 Male 4/2/2008 Sweden
Primary
Concomitant
Renal Failure Hospitalization 2/15/2008 83 Male 6/16/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Small Cell Lung Cancer Metastatic Other Serious 4/7/2006 Male 231 lb 7/1/2008 Physician Germany
Primary
Concomitant
Syncope Other Serious 4/30/2008 81 Male 6/27/2008 Sweden
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Pneumonia Life Threatening 7/9/2008 Male 9/19/2008 Consumer United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 7/9/2008 Male 9/25/2008 Consumer United Kingdom
Primary
Concomitant
Fatigue Death 11/3/2005 73 Male 10/13/2008 Physician Poland
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 2/20/1998 85 Female 12/10/2008 Physician Spain
Primary
Secondary
Chest Discomfort Life Threatening 1/5/2009 2/9/2009 Other Health Professional Singapore
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Shock Hypoglycaemic Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/25/2006 60 Male 4/1/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Shock Hypoglycaemic Life Threatening 11/14/2008 83 Male 4/8/2009 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 4/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Female 4/9/2009 Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/7/1991 Male 154 lb 4/14/2009 Germany
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 4/24/2009 Physician Canada
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 4/28/2009 Physician Canada
Primary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 150 lb 5/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/4/2008 67 Male 168 lb 5/14/2009 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/1/2009 78 Male 5/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 1/13/2009 51 Male 198 lb 7/15/2009 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Convulsion Other Serious 80 Male 150 lb 11/16/2009 Physician Canada
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/12/2009 75 Male 161 lb 11/13/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 12/1/2006 80 Male 150 lb 12/30/2009 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Gastrointestinal Infection Hospitalization 12/30/2009 75 Male 1/18/2010 Germany
Primary
Concomitant
Wound Secretion Life Threatening 10/2/2009 Male 181 lb 3/3/2010 Physician Singapore
Primary
Concomitant
Pseudomonas Infection Other Serious 1/22/2010 79 Male 187 lb 3/11/2010 Physician Germany
Primary
Concomitant
Pseudomonas Infection Other Serious 1/22/2010 79 Male 187 lb 3/18/2010 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/9/2007 72 Female 4/30/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 3/19/2010 71 Male 151 lb 5/4/2010 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 3/10/2010 70 Male 5/7/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 1/21/2009 45 Male 5/12/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Retention Other Serious 3/10/2010 70 Male 5/17/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Somnolence Hospitalization 3/10/2010 70 Male 5/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Somnolence Hospitalization 3/10/2010 70 Male 5/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Somnolence Hospitalization 3/10/2010 70 Male 5/17/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Macroglossia Other Serious 5/30/2010 87 Female 6/9/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Acquired Macroglossia Other Serious 5/30/2010 87 Female 6/11/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 4/26/2010 52 Male 209 lb 6/23/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 4/26/2010 52 Male 209 lb 6/24/2010 Physician Germany
Primary
Concomitant
Laryngeal Oedema Life Threatening 4/5/2010 78 Female 6/24/2010 Physician Germany
Primary
Concomitant
Pancytopenia Life Threatening 5/9/2010 82 Male 6/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/7/2010 86 Male 7/6/2010 Physician Sweden
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/10/2010 70 Male 181 lb 7/22/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/10/2010 70 Male 7/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/10/2010 70 Male 7/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/10/2010 70 Male 7/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Acquired Macroglossia Other Serious 5/30/2010 87 Female 7/27/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/2/2010 86 Male 132 lb 9/22/2010 Physician Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 9/7/2010 80 Female 183 lb 9/24/2010 Physician Canada
Primary
Secondary
Concomitant
Lung Infection Death Female 161 lb 10/6/2010 Consumer Brazil
Primary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 11/11/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 11/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 5/1/2010 72 Female 12/8/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Syncope Hospitalization 3/1/2010 12/23/2010 Consumer Germany
Primary
Concomitant
Syncope Hospitalization 3/1/2010 1/6/2011 Consumer Germany
Primary
Concomitant
Chronic Lymphocytic Leukaemia Death Female 181 lb 1/18/2011 Physician Germany
Primary
Concomitant
Renal Cell Carcinoma Death 7/22/2010 56 Female 1/19/2011 Physician Germany
Primary
Concomitant
Renal Cell Carcinoma Death 7/22/2010 56 Male 1/24/2011 Physician Germany
Primary
Concomitant
Sinus Bradycardia Hospitalization 2/3/2011 79 Male 248 lb 3/25/2011 Physician United States
Primary
Concomitant
Renal Injury Other Serious 9/1/1995 72 Female 109 lb 4/21/2011 Other Health Professional United States
Primary
Concomitant
Liquid Product Physical Issue Hospitalization 4/25/2011 62 Male 203 lb 5/4/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 4/25/2011 62 Male 203 lb 5/17/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 9/22/2010 83 Male 146 lb 9/24/2010 Pharmacist United States
Primary
Concomitant
Hepatic Failure Hospitalization 6/16/2011 23 Male 307 lb 8/18/2011 Physician United States
Primary
Secondary
Concomitant
Lung Transplant Hospitalization 3/1/2010 8/31/2011 Consumer Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 2/20/1998 85 Female 9/1/2011 Other Health Professional Spain
Primary
Secondary
Pulmonary Embolism Hospitalization 8/23/2011 72 Male 143 lb 10/5/2011 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/23/2011 72 Male 143 lb 10/12/2011 Physician Germany
Primary
Concomitant
Condition Aggravated Death 6/29/2009 78 Male 181 lb 10/14/2011 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/23/2011 72 Male 143 lb 10/17/2011 Physician Germany
Primary
Concomitant
Hypercalcaemia Hospitalization 12/3/2010 60 Male 143 lb 10/19/2011 Other Health Professional Germany
Primary
Concomitant
Leukopenia Hospitalization 8/23/2011 72 Male 143 lb 10/24/2011 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 8/23/2011 72 Male 143 lb 10/28/2011 Physician Germany
Primary
Concomitant
Exercise Tolerance Decreased Hospitalization 3/1/2010 10/28/2011 Consumer Germany
Primary
Concomitant
Bradycardia Hospitalization 7/14/2011 67 Male 10/31/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/4/2011 82 Female 108 lb 11/9/2011 Other Health Professional Canada
Primary
Concomitant
Pneumonia Other Serious 9/2/2011 74 Male 177 lb 11/15/2011 Physician United States
Primary
Concomitant
Hypercalcaemia Hospitalization 11/4/2011 82 Female 108 lb 12/1/2011 Other Health Professional Canada
Primary
Concomitant
Cardiac Arrest Death 5/1/2011 59 Male 12/9/2011 Physician Sweden
Primary
Concomitant
Interacting
Pancytopenia Death 1/1/2011 Female 132 lb 12/19/2011 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 12/3/2010 60 Male 143 lb 12/29/2011 Other Health Professional Germany
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization Male 322 lb 1/11/2012 Lawyer United States
Primary
Concomitant
Disease Progression Other Serious 11/23/2011 Male 207 lb 2/15/2012 Germany
Primary
Secondary
Concomitant
Mental Status Changes Death 9/2/2011 74 Male 177 lb 3/2/2012 Physician United States
Primary
Concomitant
Pancytopenia Death 12/5/2011 51 Female 132 lb 3/14/2012 Physician Germany
Primary
Concomitant
Septic Embolus Death 11/23/2011 Male 207 lb 3/15/2012 Physician Germany
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 2/15/2012 61 Male 206 lb 3/16/2012 Physician Poland
Primary
Concomitant
Rectal Cancer Hospitalization 2/15/2012 61 Male 206 lb 4/17/2012 Physician Poland
Primary
Concomitant
Gastroenteritis Hospitalization 3/1/2010 5/9/2012 Consumer Germany
Primary
Concomitant
Nasopharyngitis Hospitalization 1/12/2011 45 Female 243 lb 5/17/2012 Physician Germany
Primary
Secondary
Concomitant
Palpitations Other Serious Male 299 lb 5/29/2012 Consumer United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 2/15/2012 61 Male 206 lb 5/30/2012 Poland
Primary
Concomitant
Pelvic Abscess Other Serious 2/15/2012 61 Male 197 lb 6/12/2012 Physician Poland
Primary
Concomitant
Erythema Hospitalization 3/1/2010 6/15/2012 Physician Germany
Primary
Concomitant
Nephrolithiasis Hospitalization 5/11/2012 65 Female 189 lb 6/21/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/11/2012 65 Female 189 lb 6/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/29/2012 82 Male 7/26/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Haematochezia Other Serious 4/29/2012 8/1/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Dizziness Hospitalization 4/29/2012 82 Male 8/7/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 6/29/2012 67 Male 152 lb 8/20/2012 Physician Bulgaria
Primary
Secondary
Concomitant
Right Ventricular Failure Death 6/2011 73 Female 9/13/2012 Physician De
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/6/2012 79 Male 11/1/2012 Consumer Se
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/7/2012 86 Female 10/29/2012 Other Health Professional Es
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/23/2012 75 Male 10/29/2012 Physician Se
Primary
Secondary
Concomitant

Drug Data