Acetaminophen combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sinus Tachycardia Other Serious 12/7/2005 54 Male 201 lb 1/24/2006 Other Health Professional Canada
Primary
Concomitant
Metabolic Acidosis Other Serious 77 Male 2/9/2006 Other Health Professional Canada
Primary
Concomitant
Post Procedural Complication Hospitalization 5/28/2005 68 Female 2/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Nausea Other Serious 1/25/2006 85 Male 2/17/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Nausea Other Serious 1/25/2006 85 Male 2/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/19/2001 69 Female 115 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 3/2/2002 56 Female 3/2/2006 Norway
Primary
Concomitant
Urinary Tract Infection Other Serious 1/11/2001 69 Female 115 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/6/2005 50 Female 3/14/2006 Pharmacist Italy
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/6/2005 92 Female 3/27/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Syncope Hospitalization 2/14/2006 88 Female 132 lb 4/5/2006 Other Health Professional France
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/13/2006 87 Female 126 lb 4/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 6/17/2004 78 Male 4/21/2006 Other Health Professional Canada
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Myocardial Infarction Other Serious 12/7/2005 54 Male 201 lb 5/5/2006 Physician Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/11/2001 69 Female 115 lb 5/18/2006 Physician United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 5/3/2006 70 Male 5/18/2006 Physician France
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 5/3/2006 70 Male 6/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 4/5/2004 88 Female 110 lb 6/22/2006 Other Health Professional France
Primary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/22/2006 78 Female 7/20/2006 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Disorder Other Serious 5/2/2006 68 Male 8/3/2006 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Haemolytic Anaemia Hospitalization 3/20/2006 71 Female 9/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Intentional Overdose Other Serious 19 Female 9/13/2006 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 5/2/2006 68 Male 10/11/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 5/21/2006 Male 11/1/2006 Consumer France
Primary
Secondary
Concomitant
Tongue Dry Death 5/24/2006 51 Male 128 lb 11/14/2006 Other Health Professional Estonia
Primary
Secondary
Concomitant
Throat Cancer Other Serious 8/3/2006 Male 187 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 9/21/2006 Female 130 lb 11/20/2006 Physician Canada
Primary
Concomitant
Pneumonia Death 5/24/2006 Male 11/21/2006 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 12/7/2005 Male 201 lb 11/22/2006 Physician Canada
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 8/22/2006 Male 12/15/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 66 Male 12/19/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/29/2005 72 Male 12/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Death 8/22/2006 Male 12/26/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Intentional Overdose Other Serious 24 Male 1/3/2007 Consumer Ireland
Primary
Secondary
Vomiting Other Serious 40 Female 1/3/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 33 Female 1/3/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious Male 1/3/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 85 Male 1/3/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 20 Female 1/3/2007 Consumer Ireland
Primary
Secondary
Poor Quality Sleep Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 24 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 22 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Liver Function Test Abnormal Other Serious 46 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious 38 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 48 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 20 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Vomiting Other Serious 47 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 42 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 23 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Renal Failure Other Serious 24 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 12/7/2005 Male 201 lb 1/8/2007 Physician Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Phlebitis Hospitalization 11/2/2006 69 Male 163 lb 2/1/2007 Other Health Professional France
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Platelet Count Decreased Life Threatening 1/27/2007 65 Male 176 lb 3/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nightmare Other Serious 10/25/2006 Female 108 lb 3/19/2007 Physician France
Primary
Concomitant
Rash Other Serious 72 Male 3/26/2007 Physician United Kingdom
Primary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 7/10/2007 Other Health Professional Sweden
Primary
Concomitant
Suicide Attempt Life Threatening 10/1/2005 Female 115 lb 7/18/2007 Consumer Netherlands
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9 Male 8/3/2007 Other Health Professional Sweden
Primary
Concomitant
Rash Life Threatening 6/3/2007 20 Female 8/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 5/2/2007 78 Female 9/4/2007 Other Health Professional Sweden
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Bowel Movement Irregularity Hospitalization 8/29/2007 71 Male 11/30/2007 Physician Sweden
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious Female 176 lb 12/4/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 12/6/2007 Physician Sweden
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 11/23/2007 73 Female 143 lb 12/6/2007 Physician France
Primary
Concomitant
Basal Cell Carcinoma Other Serious 6/21/2007 Female 176 lb 12/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Thrombocythaemia Death 4/3/2007 60 Female 12/20/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Dyspnoea Other Serious 11/15/2007 69 Female 95 lb 12/24/2007 Physician United Kingdom
Primary
Concomitant
Thrombocythaemia Death 4/3/2007 60 Female 1/8/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Constipation Hospitalization 8/29/2007 71 Male 1/23/2008 Physician Sweden
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Death 1/26/2008 Female 137 lb 2/19/2008 United Kingdom
Primary
Concomitant
Thrombocythaemia Death 4/3/2007 60 Female 2/22/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Subdural Haemorrhage Death Male 187 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/25/2007 Male 163 lb 2/29/2008 United Kingdom
Primary
Concomitant
Purpura Hospitalization 11/23/2007 73 Female 3/17/2008 Physician France
Primary
Concomitant
Tremor Other Serious Male 3/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Agranulocytosis Other Serious 8/31/2007 Male 3/28/2008 Physician Germany
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 2/20/2008 84 Male 4/3/2008 Sweden
Primary
Concomitant
Tremor Other Serious 1/1/2002 Male 4/16/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/13/2008 89 Male 4/28/2008 Other Health Professional Sweden
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/1/2008 83 Female 176 lb 5/12/2008 Consumer Netherlands
Primary
Concomitant
Cerebral Haematoma Hospitalization 8/10/2006 Female 5/13/2008 France
Primary
Concomitant
Tachypnoea Hospitalization 1/1/2008 60 Male 5/16/2008 Consumer France
Primary
Secondary
Concomitant
Death Death 4/26/2008 56 Male 208 lb 5/19/2008 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/25/2008 5/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 1/1/2008 Female 5/22/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 58 Male 6/9/2008 Physician Canada
Primary
Secondary
Drug Toxicity Other Serious 25 Female 6/11/2008 Physician Canada
Primary
Secondary
Substance Abuse Other Serious 50 Male 6/11/2008 Physician Canada
Primary
Secondary
Thermal Burn Other Serious 36 Female 6/16/2008 Physician Canada
Primary
Secondary
Substance Abuse Other Serious 56 Female 6/20/2008 Canada
Primary
Secondary
Thrombocytopenia Hospitalization 8/6/2004 66 Male 151 lb 6/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 4/2/2008 67 Male 6/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 4/2/2008 67 Male 6/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/26/2008 Female 137 lb 7/3/2008 United Kingdom
Primary
Concomitant
Nausea Hospitalization 5/21/2008 Female 121 lb 7/10/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Death 66 Male 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 8/18/2008 71 Male 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious 8/1/2008 64 Male 140 lb 9/2/2008 Consumer United Kingdom
Primary
Concomitant
Hypotension Hospitalization 7/22/2008 Female 9/4/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/30/2008 Male 183 lb 9/19/2008 Canada
Primary
Secondary
Concomitant
Visual Impairment Disability 5/7/2008 Male 9/26/2008 Other Health Professional Norway
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/10/2008 Canada
Primary
Secondary
Concomitant
Pain Other Serious 8/1/2008 Female 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/5/2008 Male 10/16/2008 Consumer Germany
Primary
Secondary
Concomitant
Thrombocythaemia Death 4/3/2007 Female 10/15/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/30/2008 Male 183 lb 10/24/2008 Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 3/19/2008 51 Female 161 lb 11/7/2008 United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/3/2008 Male 11/10/2008 Physician Sweden
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/30/2008 Male 183 lb 11/14/2008 Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/13/2008 86 Male 11/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 10/1/2006 91 Male 11/18/2008 Consumer Canada
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 11/16/2008 59 Female 183 lb 11/27/2008 Sweden
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 10/4/2008 Male 12/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Joint Swelling Other Serious 10/3/2008 51 Female 12/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 12/23/2008 Physician Spain
Primary
Concomitant
Drug Toxicity Other Serious 58 Male 1/6/2009 Physician Canada
Primary
Secondary
Sudden Death Hospitalization 11/17/2008 Male 1/8/2009 Physician Belgium
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 37 Male 176 lb 1/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 1/28/2009 Physician Spain
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 11/16/2008 59 Female 183 lb 1/23/2009 Sweden
Primary
Concomitant
Muscle Twitching Other Serious 11/14/2008 60 Male 2/5/2009 Physician Norway
Primary
Secondary
Concomitant

Drug Data