Acetaminophen combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Disability 2/22/2005 87 Male 169 lb 1/10/2006 Pharmacist United States
Primary
Concomitant
Epistaxis Required Intervention 12/30/2005 82 Male 189 lb 1/9/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Disability 3/10/2005 87 Male 169 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Faeces Discoloured Hospitalization 11/21/2005 86 Male 197 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 2/6/2006 77 Male 2/15/2006 Physician Japan
Primary
Concomitant
Atrial Fibrillation Other Serious 7/15/2005 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Complication Hospitalization 5/28/2005 68 Female 2/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome Other Serious 12/8/2005 84 Female 2/10/2006 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2003 75 Male 3/14/2006 Lawyer United Kingdom
Primary
Concomitant
Tachycardia Other Serious 11/1/2003 75 Male 3/22/2006 Physician United Kingdom
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Rectal Haemorrhage Hospitalization 12/9/2005 76 Female 183 lb 4/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/1/2002 71 Female 146 lb 4/28/2006 Physician Canada
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 7/5/2005 81 Female 141 lb 5/11/2006 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Hyperhidrosis Other Serious 48 Male 5/18/2006 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 9/21/2006 Physician Japan
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Syncope 1/1/2005 19 Male 104 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Lung Disorder 6/1/2006 19 Male 93 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Vomiting 4/18/2006 40 Female 260 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/31/2008 79 Female 4/30/2008 Physician France
Primary
Secondary
Concomitant
Cyst Other Serious Female 234 lb 5/20/2008 Consumer United Kingdom
Primary
Concomitant
Impaired Healing Other Serious 6/13/2008 80 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 8/15/2008 Male 159 lb 12/26/2008 United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 12/26/2006 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 12/26/2006 72 Female 1/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Vasculitis Hospitalization 10/21/2008 1/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 108 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/7/2009 72 Female 1/31/2009 Other Health Professional Germany
Primary
Secondary
Pulmonary Embolism Death 1/8/2009 58 Female 2/5/2009 Other Health Professional United States
Primary
Concomitant
Arterial Haemorrhage Life Threatening 10/30/2007 Male 157 lb 2/6/2009 Physician Canada
Primary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Rash Other Serious 11/12/2008 70 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 96 Female 112 lb 2/24/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 4/2/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death Male 4/8/2009 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/21/2008 Male 207 lb 4/30/2009 Physician Australia
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/1/2005 65 Female 250 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 3/28/2009 Male 175 lb 5/21/2009 Pharmacist United States
Primary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Incorrect Route Of Drug Administration Other Serious 81 Female 6/10/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/26/2008 70 Male 6/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 108 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 53 Male 7/7/2009 Hong Kong
Primary
Concomitant
Interacting
Dyspnoea Hospitalization 1/7/2009 72 Male 7/31/2009 United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 6/26/2009 Male 190 lb 8/11/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Memory Impairment Hospitalization 90 Female 8/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Loss Of Consciousness Life Threatening 6/12/2009 Male 219 lb 8/25/2009 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 6/30/2009 Male 190 lb 8/28/2009 Physician United States
Primary
Concomitant
Surgery Hospitalization 90 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 79 Male 9/4/2009 Physician United States
Primary
Secondary
Concomitant
Weaning Failure Hospitalization 79 Male 9/12/2009 Physician United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Weight Increased Other Serious 31 Male 9/15/2009 United States
Primary
Concomitant
Pelvic Infection Required Intervention 6/23/2009 25 Female 178 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Pallor Life Threatening 8/10/2009 64 Male 195 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 60 Male 215 lb 9/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 9/28/2009 Physician Australia
Primary
Secondary
Concomitant
White Clot Syndrome Other Serious 11/11/2007 67 Male 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Peripheral Vascular Disorder Death Female 9/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/9/2009 Female 10/5/2009 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Multiple Injuries Other Serious 87 Female 12/11/2009 United States
Primary
Concomitant
Urticaria Other Serious 7/23/2009 Female 1/13/2010 Physician United States
Primary
Concomitant
Overdose Death 89 Female 1/22/2010 Physician United States
Primary
Secondary
Transient Ischaemic Attack Other Serious 2/24/2009 Female 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 89 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Adverse Drug Reaction Death 79 Male 1/26/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/2/2010 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 57 Male 127 lb 4/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 5/7/2010 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 1/1/2010 81 Male 128 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 4/16/2009 79 Male 125 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization Male 5/17/2010 Consumer United States
Primary
Concomitant
Lipase Increased Other Serious 2/14/2008 82 Female 132 lb 5/28/2010 Physician Canada
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 45 Female 6/11/2010 Lawyer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2007 73 Male 234 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 3/1/2008 74 Male 6/15/2010 Lawyer United States
Primary
Concomitant
Nausea Hospitalization Male 214 lb 6/16/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/9/2010 69 6/16/2010 Pharmacist Ireland
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/7/2009 66 Male 241 lb 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Clot Syndrome Other Serious Male 175 lb 6/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/19/2009 78 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Nausea Hospitalization Male 214 lb 7/2/2010 Physician United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 6/6/2010 78 Male 7/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 12/16/2007 86 Female 113 lb 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Sunburn Other Serious 6/4/2010 57 Male 290 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 7/29/2010 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 5/22/2005 45 Female 200 lb 7/29/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/4/2007 63 Female 218 lb 8/4/2010 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 75 Female 170 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/1/2008 55 Female 8/9/2010 Other Health Professional United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2010 65 Female 254 lb 8/5/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2007 73 Male 234 lb 8/12/2010 Lawyer United States
Primary
Concomitant
Syncope Other Serious 7/1/2008 84 Female 8/12/2010 Lawyer United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2008 65 Male 258 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/1984 74 Male 8/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tinea Versicolour Hospitalization 3/28/2010 82 Male 8/13/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2009 81 Male 175 lb 8/13/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 71 Male 8/18/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/23/2007 53 Female 198 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophagia Other Serious 4/8/2010 81 Female 125 lb 8/16/2010 Pharmacist United States
Primary
Concomitant
Haemarthrosis Hospitalization 7/22/2010 79 Male 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/1/2010 70 Male 8/20/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 4/17/2002 55 Female 8/20/2010 United States
Primary
Concomitant
Stomatitis Hospitalization 72 Male 8/24/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 8/25/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/25/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 8/1/2007 77 Male 9/8/2010 Lawyer United States
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/1/2010 80 Female 155 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 5/17/2010 72 Male 194 lb 9/24/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Death Death 80 Male 214 lb 9/28/2010 Consumer United States
Primary
Concomitant
Shock Death Female 10/21/2010 Physician United States
Primary
Concomitant
Myalgia 10/1/2009 85 Female 166 lb 10/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Sepsis Hospitalization Female 11/1/2010 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 11/2/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 83 Female 187 lb 11/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 4/21/2010 67 Male 11/5/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/12/2008 34 Female 154 lb 11/8/2010 Lawyer United States
Primary
Concomitant
Diarrhoea Hospitalization Male 11/8/2010 Consumer Sweden
Primary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant

Drug Data