Acetaminophen combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Vomiting Disability 2/16/2005 88 Male 187 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Vomiting Hospitalization 12/26/2005 75 Female 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2005 75 Female 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 7/6/2005 66 Male 173 lb 12/7/2005 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/24/2005 71 Female 12/6/2005 Pharmacist United States
Primary
Concomitant
Dyspnoea Life Threatening 1/3/2005 27 Female 132 lb 2/3/2006 Consumer Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/22/2005 73 Female 2/8/2006 United Kingdom
Primary
Concomitant
Faeces Discoloured Hospitalization 11/21/2005 86 Male 197 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Palpitations Other Serious 1/13/2006 Female 216 lb 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Field Defect Other Serious 1/1/2006 74 Male 2/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/6/2006 54 Female 260 lb 2/16/2006 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Urosepsis Hospitalization 7/20/2005 66 Male 2/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/13/2005 56 Male 181 lb 2/24/2006 Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Death 72 Female 110 lb 2/24/2006 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 1/31/2006 81 Male 3/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/6/2006 77 Male 110 lb 3/10/2006 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 1/25/2005 77 Male 148 lb 3/13/2006 Other Health Professional United States
Primary
Concomitant
Transfusion Reaction Death 8/13/2002 58 Female 155 lb 3/14/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/7/2006 75 Female 4/4/2006 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/6/2006 77 Male 110 lb 4/11/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 6/13/2003 54 Female 170 lb 2/14/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/7/2006 75 Female 201 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 4/1/2004 94 Female 97 lb 4/17/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 7/20/2005 66 Male 4/4/2006 United States
Primary
Secondary
Concomitant
Influenza Other Serious 10/24/2005 24 Male 128 lb 4/17/2006 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 3/20/2006 Male 184 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pallor Hospitalization 4/15/2006 87 Female 4/19/2006 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 Male 209 lb 5/8/2006 Lawyer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 72 Female 256 lb 5/5/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 Male 209 lb 5/10/2006 Lawyer Canada
Primary
Concomitant
Status Epilepticus Required Intervention 3/7/2006 54 Female 180 lb 3/16/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Disability 3/28/2006 61 Female 5/10/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 56 Female 5/12/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/7/2006 75 Female 201 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/3/2006 68 Female 123 lb 5/23/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2005 75 Female 6/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 8/12/2005 79 Female 137 lb 6/1/2006 Physician Australia
Primary
Concomitant
Sleep Disorder Disability 4/6/2006 65 Female 97 lb 6/7/2006 Pharmacist United Kingdom
Primary
Concomitant
Drug Ineffective 1/1/2006 77 Male 5/5/2006 Consumer United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 3/20/2006 58 Female 6/15/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2005 75 Female 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 56 Female 6/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Procedural Complication Other Serious 1/1/2004 74 Female 130 lb 7/7/2006 United States
Primary
Concomitant
Hepatic Enzyme Abnormal Other Serious 2/15/2006 83 Male 230 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Hospitalization 6/9/2006 68 Male 7/17/2006 Physician France
Primary
Concomitant
Hypotension Hospitalization 4/24/2006 79 Male Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 4/23/2006 66 Female 124 lb Pharmacist United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/27/2006 71 Female 139 lb 7/14/2006 Physician Portugal
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Oedema Peripheral 89 Female 7/21/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/18/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/8/2006 31 Female 187 lb 6/22/2006 Other Health Professional United States
Primary
Concomitant
Melaena Hospitalization 7/2/2006 59 Male 165 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Intraventricular Haemorrhage Death 8/3/2003 74 Female 119 lb 7/20/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/21/2006 85 Female 180 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/23/2006 66 Female 124 lb Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/27/2006 Denmark
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/7/2006 Physician United Kingdom
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/10/2006 Male 153 lb 8/8/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/29/2005 71 Male 217 lb 7/28/2006 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 6/25/2006 26 Female 113 lb 8/11/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2006 67 Male 8/18/2006 Physician United Kingdom
Primary
Concomitant
Vulval Disorder Hospitalization 8/2/2006 29 Female 108 lb 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/19/2006 68 Male 247 lb 8/22/2006 Pharmacist United States
Primary
Secondary
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Urticaria Hospitalization 8/2/2006 29 Female 108 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Lesion Hospitalization 8/2/2006 29 Female 108 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Irritation 13 Female 154 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/22/2006 67 Female 9/28/2006 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 6/28/2006 80 Male 108 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pallor Other Serious 4/15/2006 87 Female 9/8/2006 Consumer Canada
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/4/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 64 Female 10/6/2006 Physician Australia
Primary
Concomitant
Swelling Face Other Serious 9/14/2006 65 Male 10/11/2006 Consumer United Kingdom
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Hypotension Other Serious 48 Male 10/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/12/2006 65 Male 183 lb 10/6/2006 Physician United Kingdom
Primary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 8/1/2006 51 Male 10/9/2006 United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 10/18/2006 Physician Japan
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/12/2006 United Kingdom
Primary
Secondary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/19/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea 6/27/2006 76 Female 8/22/2006 United States
Primary
Concomitant
Po2 Decreased Life Threatening 7/21/2006 70 Female 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Hospitalization 51 Male 10/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache 6/8/2006 Male 10/30/2006 Consumer United States
Primary
Concomitant
Pollakiuria Other Serious 7/1/2006 65 Female 88 lb 10/17/2006 Physician United Kingdom
Primary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 9/12/2006 65 Male 183 lb 10/24/2006 Physician United Kingdom
Primary
Concomitant
Oesophageal Ulcer Haemorrhage Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Hospitalization 4/27/2006 56 Female 10/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 99 lb 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 11/6/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Humerus Fracture Disability 8/1/2006 89 Female 11/2/2006 Consumer United Kingdom
Primary
Concomitant
Throat Cancer Other Serious 8/3/2006 Male 187 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 11/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 10/1/2006 Male 11/16/2006 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/23/2006 70 Female 11/17/2006 Consumer United States
Primary
Concomitant
Swollen Tongue Required Intervention 8/2/2006 25 Male 198 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Cervical Vertebral Fracture Hospitalization Female 100 lb 11/22/2006 Consumer Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Hospitalization 4/1/2006 55 Female 11/16/2006 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/10/2006 75 Male 231 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 10/24/2006 Male 11/30/2006 Other Health Professional United Kingdom
Primary
Interacting
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 10/24/2006 Male 11/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Subclavian Vein Thrombosis Hospitalization 8/19/2005 Male 12/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/1986 Male 212 lb 12/1/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 66 Male 12/13/2006 United States
Primary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Upper Limb Fracture Life Threatening Female 12/15/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Upper Respiratory Tract Infection Hospitalization 7/28/2006 77 Female 88 lb 12/15/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 66 Male 12/19/2006
Primary
Secondary
Concomitant
Sedation Life Threatening 5/29/2006 82 Male 12/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 12/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/27/2005 68 Male 212 lb 12/19/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/26/2005 75 Female 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/24/2006 67 Female 12/22/2006 Pharmacist Japan
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 19 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 50 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious 20 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 20 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Vomiting Other Serious 9/1/2006 Female 1/5/2007 Physician Fiji
Primary
Secondary
Concomitant
Overdose Other Serious 11/30/2005 69 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 7/5/2006 77 Male 185 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/25/2006 87 Female 107 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 16 Female 113 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Spinal Epidural Haemorrhage Hospitalization 11/30/2006 80 Female 1/17/2007 Other Health Professional Norway
Primary
Secondary
Concomitant

Drug Data