Acetaminophen combined with Valproic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Death 1/1/1997 20 Female 1/6/2006 Physician United States
Primary
Concomitant
Weight Decreased Disability 82 Male 1/25/2006 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 8/15/2005 40 Female 1/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sedation Life Threatening 6/15/2005 40 Female 1/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness Death 5 Female 3/9/2006 United States
Primary
Secondary
Completed Suicide Death 28 3/9/2006 United States
Primary
Secondary
Vomiting Hospitalization 23 Female 3/9/2006 United States
Primary
Secondary
Loss Of Consciousness Hospitalization 51 Female 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Unknown 3/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/10/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasospasm Other Serious 3/23/2006 Male 234 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Anticonvulsant Drug Level Below Therapeutic Other Serious 8/1/2005 Female 179 lb 5/1/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 67 Male 202 lb 3/9/2006 United States
Primary
Concomitant
Hypertension Hospitalization 3/25/2006 76 Female 170 lb 7/21/2006 Physician Switzerland
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 10/28/2004 77 Female 140 lb 7/28/2006 France
Primary
Secondary
Concomitant
Somnolence Death 6/14/2006 89 8/2/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/31/2006 62 Female 140 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Weight Increased 10/1/2004 48 Male 285 lb 8/8/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 8/9/2006 54 Female 170 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 26 Female 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 61 Female 9/15/2006 Physician United States
Primary
Secondary
Neuroleptic Malignant Syndrome 8/15/2006 79 Male 138 lb 9/27/2006 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered Death 61 9/29/2006 Physician United States
Primary
Secondary
Weight Increased 10/1/2004 48 Male 285 lb 10/17/2006 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/8/2006 Lawyer United States
Primary
Concomitant
Completed Suicide Death 61 11/9/2006 United States
Primary
Secondary
Completed Suicide Death 40 11/9/2006 United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/13/2006 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/16/2006 Physician United States
Primary
Concomitant
Poisoning Death 40 11/16/2006 Physician United States
Primary
Secondary
Poisoning Death 61 11/16/2006 Physician United States
Primary
Secondary
Death Death 1/1/2005 40 Unknown 2/7/2007 Physician United States
Primary
Secondary
Death Death 1/1/2005 61 Unknown 2/8/2007 Physician United States
Primary
Secondary
Drug Level Decreased Other Serious 1/3/2006 80 Female 163 lb 3/23/2007 France
Primary
Secondary
Concomitant
Interacting
Rhabdomyolysis Required Intervention 19 Male 8/21/2004 United States
Primary
Concomitant
Pyrexia Death 1/1/2000 5 Female 4/26/2007 United States
Primary
Secondary
Influenza Like Illness Death 5 Female 4/26/2007 United States
Primary
Secondary
Priapism Other Serious 4/21/2007 50 Male 138 lb 6/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Transplant Rejection Life Threatening 6/13/2007 57 Female 7/25/2007 United Kingdom
Primary
Concomitant
Completed Suicide Death 40 10/29/2007 Physician United States
Primary
Secondary
Hepatotoxicity Hospitalization 1 Male 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 1 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 3 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 44 Female 1/15/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 60 Female 1/29/2008 Germany
Primary
Secondary
Drug Toxicity Death 60 Female 1/29/2008 Germany
Primary
Secondary
Completed Suicide Death 1/1/2006 44 Female 1/28/2008 Physician United States
Primary
Secondary
Completed Suicide Death 44 Female 2/8/2008 United States
Primary
Secondary
Poisoning Death 44 Female 2/6/2008 Physician United States
Primary
Secondary
Completed Suicide Death 44 Female 2/5/2008 Physician United States
Primary
Secondary
Unresponsive To Stimuli Other Serious 2/15/2008 72 Female 2/28/2008 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 3/13/2008 Physician United States
Primary
Secondary
Status Epilepticus Hospitalization 1 Male 3/28/2008 Netherlands
Primary
Secondary
Concomitant
Rash Hospitalization 11/29/2007 Male 6/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 10 Male 7/2/2008 Italy
Primary
Concomitant
Pneumonia Hospitalization 6/21/2006 Male 223 lb 7/9/2008 United Kingdom
Primary
Concomitant
Renal Tubular Disorder Other Serious 10 Male 8/5/2008 Italy
Primary
Concomitant
Liver Injury Other Serious 4 Male 8/12/2008 Other Health Professional Netherlands
Primary
Secondary
Cardiac Arrest Death 39 Male 9/16/2008 United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3 Female 9/29/2008 United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 11/26/2008 Consumer Colombia
Primary
Concomitant
Chest Pain Hospitalization 11/12/2008 60 Female 12/2/2008 Consumer Colombia
Primary
Concomitant
Drug Toxicity Death 26 Female 12/24/2008 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 31 Female 12/29/2008 Physician United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/8/2009 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2007 31 Female 1/15/2009 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2007 31 Female 1/15/2009 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 31 Female 1/16/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 26 Female 1/16/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 39 Female 1/16/2009 United States
Primary
Secondary
Completed Suicide Death 26 Female 1/22/2009 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/23/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 39 Female 1/23/2009 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 1/28/2009 Other Health Professional United States
Primary
Secondary
Drug Abuse Death 31 Female 1/30/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 39 Female 1/26/2009 Physician United States
Primary
Secondary
Poisoning Death 31 Female 1/26/2009 Physician United States
Primary
Secondary
Death Death 1/1/2007 31 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 39 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Death Death 31 Female 1/30/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Death 39 Female 2/13/2009 Physician United States
Primary
Secondary
Death Death 31 Female 2/13/2009 Physician United States
Primary
Secondary
Urinary Incontinence Other Serious 12/15/2008 Female 3/6/2009 Canada
Primary
Concomitant
Respiratory Arrest Death 39 Female 3/5/2009 Physician United States
Primary
Secondary
Completed Suicide Death 26 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Death Death 31 Female 3/20/2009 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 4/1/2009 Male 261 lb 4/9/2009 United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/15/2008 Female 4/13/2009 Physician Canada
Primary
Concomitant
Pneumonia Other Serious 26 Female 5/13/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 32 Female 6/18/2009 Pharmacist Netherlands
Primary
Concomitant
Ventricular Hypokinesia Other Serious 4/17/2009 1 Male 12 lb 6/22/2009 Physician Brazil
Primary
Concomitant
Sopor Hospitalization 7 Female 6/25/2009 Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 19 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Bronchiolitis Other Serious 3 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 1 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 1 Male 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 2 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 41 Male 303 lb 7/30/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 32 Female 8/3/2009 Pharmacist Netherlands
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/1/2009 49 Female 252 lb 8/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 8/28/2009 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2009 Female 9/2/2009 Pharmacist Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Male 286 lb 10/15/2009 United States
Primary
Concomitant
Hyponatraemia Other Serious 7/9/2009 51 Female 11/4/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 60 Female 198 lb 12/4/2009 Other Health Professional Belgium
Primary
Concomitant
Platelet Count Decreased Disability 4/15/2009 50 Female 157 lb 12/10/2009 Pharmacist United States
Primary
Concomitant
Poisoning Death 53 Female 1/20/2010 Physician United States
Primary
Secondary
Adverse Drug Reaction Hospitalization 53 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Suicide Attempt Other Serious 31 Female 1/22/2010 Netherlands
Primary
Concomitant
Completed Suicide Death 26 Female 2/3/2010 United States
Primary
Secondary
Hepatitis Hospitalization 60 Female 198 lb 2/4/2010 Other Health Professional Belgium
Primary
Concomitant
Pyrexia Death 1/1/2000 5 Female 2/5/2010 Pharmacist United States
Primary
Secondary
Unevaluable Event Death 12/1/2009 53 Female 2/1/2010 Physician United States
Primary
Secondary
Adverse Drug Reaction Death 53 Female 2/2/2010 United States
Primary
Secondary
Poisoning Death 1/1/2008 53 Female 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 41 Male 2/22/2010 United States
Primary
Secondary
Thrombocytopenia Other Serious 9/30/2009 43 Male 2/18/2010 Pharmacist United States
Primary
Concomitant
Adverse Drug Reaction Death 53 Female 2/23/2010 United States
Primary
Secondary
Sinus Bradycardia Other Serious 32 Female 2/9/2010 Netherlands
Primary
Concomitant
Sinus Bradycardia Other Serious 32 Female 2/9/2010 Pharmacist Netherlands
Primary
Concomitant
Multiple Drug Overdose Death 9/27/2003 Male 182 lb 2/28/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 45 Female 120 lb 3/1/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 45 Female 120 lb 3/2/2010 Physician United States
Primary
Secondary
Adverse Drug Reaction Death 53 Female 3/5/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 53 Female 3/30/2010 Other Health Professional United States
Primary
Secondary
Drug Level Below Therapeutic Other Serious 63 Male 190 lb 7/27/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 7/29/2010 United States
Primary
Secondary
Concomitant
Gout Other Serious 1/1/2008 56 Female 100 lb 8/12/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 54 Male 8/23/2010 United States
Primary
Secondary
Concomitant

Drug Data