Acetaminophen combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Dependence Hospitalization 58 Male 1/17/2006 France
Primary
Secondary
Concomitant
Nutritional Condition Abnormal Hospitalization 58 Male 2/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 51 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/30/2005 64 Male 177 lb 2/8/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/18/2005 56 Female 5/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 2/13/2006 50 Female 5/12/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/8/2005 59 Female 3/22/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/30/2006 54 Female 5/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/13/2005 48 Male 1/13/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/8/2005 53 Male 1/13/2006 United States
Primary
Concomitant
Somnolence Hospitalization 6/14/2006 89 Unknown 8/4/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/26/2006 85 Female 8/24/2006 United Kingdom
Primary
Secondary
Concomitant
Malaise Disability 7/14/2006 49 Female 108 lb 8/30/2006 Physician Japan
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 4/14/2005 58 Female 11/23/2006 Physician New Zealand
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/30/2006 42 Male 154 lb 11/14/2006 France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Multiple Drug Overdose Hospitalization 12/4/2006 Other Health Professional United States
Primary
Secondary
Mydriasis Hospitalization 39 Female 1/4/2007 Consumer Ireland
Primary
Secondary
White Blood Cell Disorder Hospitalization 11/8/2006 74 Male 1/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/19/2005 49 Male 3/8/2007 Other Health Professional Germany
Primary
Concomitant
Drug Level Decreased Other Serious 1/3/2006 80 Female 163 lb 3/22/2007 Pharmacist Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 55 Male 189 lb 5/29/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 4/5/2005 2 Female 22 lb 6/20/2007 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/13/2007 57 Female 7/27/2007 Consumer United Kingdom
Primary
Concomitant
Transplant Rejection Life Threatening 6/13/2007 57 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/30/2006 51 Male 9/12/2007 Australia
Primary
Concomitant
Syncope Hospitalization 11/23/2007 56 Male 2/11/2008 Other Health Professional Australia
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/14/2004 33 Female 2/21/2008 Germany
Primary
Secondary
Concomitant
Sudden Unexplained Death In Epilepsy Death 9/6/2006 29 Male 2/12/2008 Consumer United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/12/2004 Female 2/27/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/1/2004 33 Female 2/28/2008 Consumer United States
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 2/28/2008 Denmark
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/24/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Hospitalization 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 10/14/2004 Female 3/25/2008 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 3/28/2008 Canada
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 3/31/2008 Denmark
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 4/9/2008 Physician Denmark
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 66 Female 5/30/2008 Other Health Professional France
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 6/19/2008 Canada
Primary
Concomitant
Melaena Hospitalization 8/2/2005 69 Female 6/17/2008 Denmark
Primary
Secondary
Concomitant
Death Death 1/1/2008 Male 7/7/2008 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Male 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 6/29/2008 64 Male 7/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Necrosis Death 11 8/15/2008 Other Health Professional Australia
Primary
Secondary
Liver Injury Hospitalization 8/20/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Tendon Rupture Required Intervention 4/30/2006 51 Male 8/15/2008 Australia
Primary
Concomitant
Pruritus Generalised 11/28/2007 Female 162 lb 8/27/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 39 Male 9/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/23/2008 United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 39 Male 9/23/2008 United Kingdom
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 11/16/2007 Female 126 lb 10/2/2008 United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
Somnolence Other Serious 7/2/2006 89 10/22/2008 Denmark
Primary
Concomitant
Suicide Attempt Hospitalization 10/27/2008 Female 198 lb 10/29/2008 Physician Germany
Primary
Secondary
Tachycardia Hospitalization 10/27/2008 Female 198 lb 11/18/2008 Physician Germany
Primary
Secondary
Dysphagia Other Serious Male 11/20/2008 Pharmacist United Kingdom
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Confusional State Other Serious 63 Female 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Intravascular Haemolysis Life Threatening 12/22/2008 68 Male 176 lb 1/26/2009 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/15/2009 Female 2/24/2009 Physician Germany
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/6/2009 Other Health Professional France
Primary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 223 lb 3/24/2009 United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 25 Male 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 6/2/2009 United Kingdom
Primary
Concomitant
Sopor Hospitalization 7 Female 6/25/2009 Netherlands
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Death 9/15/2009 51 Male 230 lb 9/25/2009 Physician Australia
Primary
Concomitant
Syncope Hospitalization 11/7/2008 56 Female 10/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/18/2009 69 Female 105 lb 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 40 Female 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Premature Baby Hospitalization 2/15/2002 Female 6 lb 5/19/2010 Physician United Kingdom
Primary
Concomitant
Viral Infection Other Serious 2/23/2004 24 Male 154 lb 6/21/2010 Physician United Kingdom
Primary
Concomitant
Convulsion Hospitalization 5/24/2010 38 Female 8/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/28/2010 11 Female 65 lb 9/10/2010 Other Health Professional Australia
Primary
Concomitant
Tachycardia Other Serious 8/7/2010 67 Female 134 lb 9/10/2010 Physician Spain
Primary
Concomitant
Confusional State Hospitalization 7/21/2009 65 Male 255 lb 11/12/2010 Consumer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 5/13/2010 55 Male 151 lb 11/29/2010 United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 5/13/2010 55 Male 152 lb 1/4/2011 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/29/2010 25 Male 2/2/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 4/5/2011 43 Male 4/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization Male 5/3/2011 Pharmacist Ireland
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 4/28/2011 47 Female 261 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 10/28/2010 Male 18 lb 6/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haematuria Hospitalization Male 6/6/2011 Physician Canada
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/9/2011 4 Male 6/8/2011 Physician South Africa
Primary
Secondary
Concomitant
Impaired Gastric Emptying Death 1/2/2006 31 Male 6/1/2011 Pharmacist United Kingdom
Primary
Concomitant
Sedation Other Serious 10/17/2005 44 Female 6/13/2011 Consumer United Kingdom
Primary
Concomitant
Dizziness Hospitalization Female 6/14/2011 Physician France
Primary
Concomitant
Hemiparesis Disability 2/1/2007 47 Male 6/16/2011 Consumer United Kingdom
Primary
Concomitant
Kidney Infection Hospitalization Male 6/9/2011 Pharmacist Ireland
Primary
Concomitant
Neutropenia Hospitalization 5/6/2011 75 Male 6/13/2011 Other Health Professional United Kingdom
Concomitant
Neutropenia Hospitalization 5/6/2011 75 Male 6/15/2011
Primary
Concomitant
T-cell Lymphoma Other Serious 6/14/2011 71 Female 8/1/2011 Physician France
Primary
Concomitant
Pneumonia Death 10/18/2005 66 Male 8/8/2011 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/2/2011 50 Female 8/8/2011 Physician Italy
Primary
Secondary
T-cell Lymphoma Other Serious 6/14/2011 71 Female 157 lb 8/12/2011 Physician France
Primary
Concomitant
Inferior Vena Caval Occlusion Hospitalization 7/7/2011 55 Female 163 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperammonaemia Death Female 9/15/2011 Consumer United Kingdom
Primary
Concomitant
Pneumonia Death 12/23/2010 21 Female 9/21/2011 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/20/2011 46 Male 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Constipation Other Serious 79 Male 9/28/2011 Physician Poland
Primary
Secondary
Thrombocytopenia Other Serious 8/2/2011 66 Female 9/30/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 9/15/2011 36 Female 118 lb 10/3/2011 Physician United Kingdom
Primary
Concomitant
T-cell Lymphoma Other Serious 6/22/2011 71 Female 157 lb 10/12/2011 Physician France
Primary
Concomitant
Hypothermia Hospitalization 8/30/2011 3 Male 43 lb 10/20/2011 Physician Germany
Primary
Concomitant
Cardiac Arrest Hospitalization 8/23/2011 51 Male 10/27/2011 Physician United Kingdom
Primary
Concomitant
Intracranial Pressure Increased Hospitalization 10/5/2011 39 Male 118 lb 10/27/2011 Physician Thailand
Primary
Concomitant
Overdose Other Serious 12/30/2009 55 Female 128 lb 10/28/2011 Pharmacist France
Primary
Concomitant
Encephalitis Disability 11/1/2009 13 Female 142 lb 10/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Other Serious 12/30/2009 55 Female 128 lb 11/2/2011 Pharmacist France
Primary
Concomitant
Infusion Related Reaction Hospitalization 9/28/2011 18 Female 11/4/2011 Physician France
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 10/13/2011 39 Male 118 lb 11/14/2011 Physician Thailand
Primary
Concomitant
Pancreatitis Acute Disability 28 Female 11/15/2011 Physician United Kingdom
Primary
Concomitant
Nausea Hospitalization 6/1/2011 55 Male 12/19/2011 Physician United States
Primary
Concomitant
Confusional State Hospitalization 7/21/2009 65 Male 255 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/15/2011 48 Male 227 lb 1/3/2012
Primary
Concomitant
Neutropenia Other Serious 11/15/2011 48 Male 227 lb 1/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 29 Male 132 lb 1/18/2012 Other Health Professional Australia
Primary
Secondary
Death Death Male 162 lb 1/25/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 10/10/2011 88 Male 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious Female 2/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Hospitalization 9/28/2011 73 Female 154 lb 2/6/2012 Physician Germany
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 12/13/2011 2/7/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 12/13/2011 52 Female 2/9/2012 Physician United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 12/13/2011 52 Female 2/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Lymphocyte Count Decreased Other Serious 12/13/2011 52 Female 2/9/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Dystonia Other Serious 12/13/2011 52 Female 2/8/2012 Other Health Professional
Primary
Secondary
Concomitant
Dystonia Other Serious 12/13/2011 52 Female 2/15/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Lymphocyte Count Decreased Other Serious 12/13/2011 52 Female 2/14/2012 Other Health Professional
Primary
Secondary
Concomitant
Neutropenia Other Serious 52 Female 2/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Hospitalization 36 Female 2/23/2012 Other Health Professional Australia
Primary
Concomitant

Drug Data