Acetaminophen combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 Male 209 lb 5/8/2006 Lawyer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 Male 209 lb 5/10/2006 Lawyer Canada
Primary
Concomitant
Urine Ketone Body Present Required Intervention 5/20/2003 28 Female 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 35 Female 6/15/2006 Other Health Professional United States
Primary
Secondary
Vomiting Required Intervention 5/20/2003 28 Female 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/18/2006 46 Female 153 lb 7/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Death 32 Female 9/13/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 32 Female 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/5/2006 59 Female 143 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 59 Female 143 lb 9/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 59 Female 143 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/14/2006 40 Female 10/19/2006 Physician Sweden
Primary
Concomitant
Fatigue Other Serious 9/14/2006 40 Female 10/27/2006 Other Health Professional Sweden
Primary
Concomitant
Intentional Overdose Other Serious 35 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Gastrostomy Tube Insertion Hospitalization 2/5/2007 Male 21 lb 2/16/2007 Physician United States
Primary
Concomitant
Wheezing Required Intervention 25 Male 3/19/2007 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Death 35 Female 4/3/2007
Primary
Secondary
Thyroid Disorder Death 39 Female 178 lb 4/5/2007 Other Health Professional United States
Primary
Secondary
Gastrostomy Tube Insertion Hospitalization 2/5/2007 Male 21 lb 7/20/2007 Physician United States
Primary
Concomitant
Migraine Hospitalization 4/23/2007 49 Male 7/23/2007 Consumer Canada
Primary
Concomitant
Failure To Thrive Hospitalization 2/5/2007 Male 21 lb 9/27/2007 Physician United States
Primary
Concomitant
Failure To Thrive Hospitalization 2/5/2007 Male 21 lb 11/8/2007 Physician United States
Primary
Concomitant
Failure To Thrive Hospitalization 2/5/2007 Male 21 lb 12/6/2007 Physician United States
Primary
Concomitant
Hepatotoxicity Hospitalization 1 Male 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 1 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 3 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/5/2007 18 Female 12/6/2007 United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 1/11/2008 Female 106 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 60 Female 106 lb 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/24/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Liver Injury Hospitalization 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vertigo Other Serious 60 Female 106 lb 3/21/2008 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 1 Male 3/28/2008 Netherlands
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 4/15/2008 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/2/2008 Consumer United Kingdom
Primary
Concomitant
No Adverse Event 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Accidental Exposure 5/23/2008 Female 150 lb 6/13/2008 United States
Primary
Concomitant
Substance Abuse Other Serious 31 Male 6/23/2008 Canada
Primary
Secondary
Trigeminal Nerve Disorder Hospitalization 39 Female 6/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Expired Drug Administered Other Serious 2/20/2008 13 Female 7/1/2008 Pharmacist France
Primary
Concomitant
Nasopharyngitis Hospitalization 1/1/2004 Male 190 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Joint Sprain 5/31/2008 Male 258 lb 9/2/2008 Physician United States
Primary
Concomitant
Foot Fracture 5/1/2008 Female 185 lb 9/13/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Foot Fracture 5/1/2008 Female 185 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 10/15/2005 Female 112 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 10/23/2008 Male 176 lb 12/16/2008 Pharmacist France
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 39 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/8/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 39 Female 1/16/2009 United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/23/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 39 Female 1/23/2009 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 1/28/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 39 Female 1/26/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 39 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Respiratory Arrest Death 39 Female 2/13/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 39 Female 3/5/2009 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 4/1/2009 Male 261 lb 4/9/2009 United States
Primary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 4/17/2009 1 Male 12 lb 6/22/2009 Physician Brazil
Primary
Concomitant
Pneumonia Hospitalization 6/16/2009 50 Male 6/29/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 19 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Bronchiolitis Other Serious 3 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 1 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 1 Male 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 2 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Drug Delivery System Malfunction 5/23/2008 Female 150 lb 9/12/2009 United States
Primary
Concomitant
Pharyngitis 11/30/2003 58 Female 159 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 6/1/2009 48 Female 9/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/2/2009 Physician United States
Primary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/30/2009 Physician United States
Primary
Concomitant
Drug Toxicity Other Serious 34 Female 1/25/2010 Physician United States
Primary
Secondary
Completed Suicide Death 34 Female 1/25/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 34 Female 1/28/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 34 Female 2/1/2010 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 52 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 49 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 2/26/2010 Physician United States
Primary
Secondary
Vomiting 7/1/2009 39 Female 115 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 37 Female 210 lb 2/27/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 45 Female 120 lb 3/1/2010 Physician United States
Primary
Secondary
Penile Exfoliation Required Intervention 9/21/2008 38 Male 225 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 45 Female 120 lb 3/2/2010 Physician United States
Primary
Secondary
Overdose Death 43 Female 4/13/2010 Physician United States
Primary
Concomitant
Interacting
Social Avoidant Behaviour Other Serious 29 Female 160 lb 7/15/2010 Pharmacist United States
Primary
Concomitant
Hepatitis Acute Hospitalization 7/1/2010 58 Female 8/4/2010 Other Health Professional France
Primary
Secondary
Overdose Death 43 Female 8/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/13/2010 United States
Primary
Concomitant
Prothrombin Time Ratio Decreased Hospitalization 7/1/2010 58 Female 8/20/2010 United States
Primary
Secondary
Pancreatitis Acute Hospitalization 3/1/2010 58 Male 8/25/2010 France
Primary
Secondary
Pyrexia Other Serious 29 Female 160 lb 9/7/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2006 53 Female 163 lb 9/8/2010 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 3/1/2010 58 Male 9/8/2010 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 10/13/2010 United States
Primary
Concomitant
Pyrexia 40 Female 116 lb 10/22/2010 Pharmacist United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 29 Female 161 lb 10/26/2010 United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 29 Female 160 lb 10/25/2010 Pharmacist United States
Primary
Concomitant
Rash 19 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2009 46 Female 11/12/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 29 Female 161 lb 11/22/2010
Primary
Secondary
Paraesthesia 1/1/2009 12/14/2010 Physician United States
Primary
Concomitant
Psychotic Disorder Other Serious 6/20/2009 32 Male 12/1/2010 Germany
Primary
Secondary
Concomitant
Epilepsy Other Serious 40 Male 12/7/2010 Consumer United Kingdom
Primary
Concomitant
Death Death 27 Female 1/10/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 27 Female 1/19/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 27 Female 1/21/2011 Physician United States
Primary
Secondary
Death Death 27 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Death Death 27 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2009 27 Female 1/27/2011 Physician United States
Primary
Secondary
Poisoning Death 1/1/2009 27 Female 1/27/2011 Physician United States
Primary
Secondary
Drug Ineffective Hospitalization 17 Male 2/16/2011 Physician United States
Primary
Secondary
Death Death 27 Female 2/22/2011 Physician United States
Primary
Secondary
Death Death 27 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 27 Female 2/21/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 27 Female 3/23/2011 Physician United States
Primary
Secondary
Hypocalcaemia Other Serious 2/5/2011 71 Female 177 lb 4/4/2011 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 22 Female 3/21/2011 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 5/28/2010 58 Male 4/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 27 Female 3/30/2011 Physician United States
Primary
Secondary
Completed Suicide Death 63 Female 5/16/2011 Physician Canada
Primary
Secondary
Grand Mal Convulsion Hospitalization 5/7/2011 27 Female 140 lb 5/16/2011 Physician United States
Primary
Concomitant
Acute Hepatic Failure Death 7/14/2010 7 Female 5/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 28 Female 143 lb 6/5/2011 Physician Germany
Primary
Secondary
Breast Cancer Other Serious 12/22/2010 42 Female 6/24/2011 Physician France
Primary
Concomitant
Blood Pressure Diastolic Increased Other Serious 4/27/2011 55 Female 123 lb 6/29/2011 Physician United States
Primary
Concomitant
Platelet Disorder Other Serious 7/30/2010 24 Female 7/8/2011 United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 17 Male 8/1/2011 Physician United States
Primary
Secondary
Food Intolerance Other Serious 28 Female 291 lb 7/14/2011 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 12/22/2010 42 Female 8/8/2011 Other Health Professional France
Primary
Concomitant
Rash Other Serious 7/5/2011 45 Male 8/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Petit Mal Epilepsy Other Serious 8/9/2011 31 Female 181 lb 8/19/2011 Physician United States
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 172 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Discolouration Other Serious 8/1/2010 53 Female 8/18/2011 United Kingdom
Primary
Concomitant

Drug Data