Acetaminophen combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Wrong Drug Administered Hospitalization 1/5/2006 54 Female 1/26/2006 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 12/27/2005 64 Female 253 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Death 12/14/2005 40 Male 2/3/2006 Physician United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/16/2005 Female 2/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Mucosal Hospitalization 9/16/2005 51 Female 2/10/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Laceration Hospitalization 11/29/2005 Female 154 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 2/28/2006 United Kingdom
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/16/2005 51 Female 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/9/2006 84 Female 3/2/2006 Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/22/2005 41 Male 170 lb 3/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 2/5/2006 Female 3/29/2006 Pharmacist
Primary
Secondary
Concomitant
Syncope Hospitalization 2/14/2006 88 Female 132 lb 4/5/2006 Other Health Professional France
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ammonia Increased Hospitalization 2/14/2006 Male 211 lb 4/6/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Death 2/6/2006 55 Female 168 lb 4/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 2/15/2006 58 Female 214 lb 4/18/2006 Pharmacist United Kingdom
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Platelet Count Decreased Other Serious 1/23/2006 95 Female 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/14/2006 88 Female 4/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 56 Female 5/12/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/21/2005 41 Male 170 lb 5/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/15/2005 96 Female 5/17/2006 Physician Switzerland
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 1/23/2006 95 Female 5/18/2006 United Kingdom
Primary
Secondary
Concomitant
Lipase Increased Hospitalization 5/4/2006 62 Male 5/22/2006 Physician United States
Primary
Concomitant
Melaena Hospitalization 4/27/2006 56 Female 5/26/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 5/11/2005 67 Female 137 lb 5/31/2006 Physician Australia
Primary
Concomitant
Hypoproteinaemia Hospitalization 2/8/2006 76 Female 6/27/2006 France
Primary
Secondary
Concomitant
Tongue Coated 9/1/2004 80 Female 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypotension Other Serious 6/17/2006 82 Female 6/23/2006 Canada
Primary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Renal Disorder 1/1/2004 80 Male 7/21/2006 Consumer United States
Primary
Concomitant
Venous Insufficiency Other Serious 9/15/2001 61 Female 181 lb 7/26/2006 Physician France
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/21/2006 85 Female 180 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/3/2006 90 Female 7/26/2006 Physician France
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 2/8/2006 76 Female 8/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 8/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/4/2006 90 Female 8/2/2006 France
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 6/26/2006 53 Male 154 lb 8/17/2006 Consumer United States
Primary
Concomitant
Vulval Disorder Hospitalization 8/2/2006 29 Female 108 lb 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 8/2/2006 29 Female 108 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 12/12/2005 72 Female 132 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Vaginal Lesion Hospitalization 8/2/2006 29 Female 108 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/11/2006 65 Female 9/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 80 Female 10/5/2006 Netherlands
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Headache Other Serious 1/1/2005 86 Male 165 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Feeling Cold 11/22/2004 74 Female 8/22/2006 United States
Primary
Concomitant
Jaundice Hospitalization 10/9/2006 64 Female 10/23/2006 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Haemorrhage Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Hospitalization 4/27/2006 56 Female 10/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/29/2006 64 Female 11/1/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 10/16/2006 66 Female 116 lb 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Portal Vein Occlusion Hospitalization 10/9/2006 64 Female 11/3/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 11/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Neoplasm Hospitalization 10/9/2006 64 Female 11/14/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Urethral Haemorrhage Other Serious 10/30/2006 Male 181 lb 12/4/2006 Physician Czech Republic
Primary
Concomitant
Urinary Tract Infection Pseudomonal Life Threatening 6/26/2006 63 Male 11/10/2006 Romania
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/30/2006 47 Female 152 lb 12/13/2006 Physician Brazil
Primary
Secondary
Suicide Attempt Life Threatening 4/21/2005 49 Female 204 lb 12/1/2006 Other Health Professional United States
Primary
Concomitant
Arthralgia Hospitalization 11/28/2006 Female 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Death 12/14/2005 40 Male 199 lb 12/18/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Life Threatening 6/26/2006 63 Male 12/19/2006 Romania
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/9/2006 64 Female 12/20/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Overdose Other Serious 11/30/2005 69 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Jaundice Hospitalization 10/9/2006 Female 1/16/2007 Taiwan, Province Of China
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 1/30/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 5/12/2005 Male 201 lb 2/6/2007 Physician United States
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 5/1/2006 63 Male 331 lb 2/15/2007 Physician France
Primary
Concomitant
Dizziness Hospitalization 10/10/2006 Male 206 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 5/1/2006 63 Male 331 lb 2/19/2007 Physician France
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/13/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/23/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/5/2007 Physician Japan
Primary
Concomitant
Rash Erythematous Hospitalization 1/27/2007 83 Female 3/7/2007 Other Health Professional France
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/9/2007 Physician Japan
Primary
Concomitant
Telangiectasia Hospitalization 11/1/2006 68 Female 135 lb 3/9/2007 Physician Canada
Primary
Concomitant
Pancreatitis Acute Hospitalization 5/1/2006 63 Male 331 lb 3/26/2007 Physician France
Primary
Concomitant
Ulcerative Keratitis Other Serious 3/1/2007 Female 122 lb 3/26/2007 Pharmacist United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 1/27/2007 83 Female 3/29/2007 Other Health Professional France
Primary
Concomitant
Syncope 1/1/2005 19 Male 104 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/23/2007 72 Male 4/10/2007 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/23/2007 72 Male 4/16/2007 United Kingdom
Primary
Concomitant
Nausea Hospitalization 4/6/2007 Female 128 lb 4/27/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 4/27/2007 Physician Canada
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 1/24/2007 73 Male 201 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 5/1/2006 63 Male 331 lb 5/23/2007 Physician France
Primary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/28/2007 60 Female 5/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 5/23/2007 72 Male 6/4/2007 United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 3/1/2005 81 Female 6/27/2007 United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 4/6/2007 Female 128 lb 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Malformation Venous Death 63 Female 7/6/2007 New Zealand
Primary
Concomitant
Sudden Death Death 3/13/2007 63 Female 7/24/2007 New Zealand
Primary
Concomitant
Seroma Hospitalization 4/20/2006 Female 152 lb 9/6/2007 Physician Switzerland
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/26/2007 62 Male 9/13/2007 United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/26/2007 62 Male 9/12/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/25/2007 61 Female 159 lb 9/27/2007 Pharmacist United States
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Asthenia Hospitalization 5/12/2005 Male 201 lb 10/9/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 2/22/2007 80 Male 180 lb 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/30/2007 31 Male 265 lb 12/6/2007 Physician Australia
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 11/13/2004 84 Male 165 lb 1/19/2008 United Kingdom
Primary
Concomitant
Myalgia Disability 8/1/2007 1/23/2008 Consumer United States
Primary
Concomitant
Ulcer Hospitalization 12/1/2007 Male 238 lb 1/24/2008 Consumer United States
Primary
Concomitant
Death Death 12/16/2007 Male 1/29/2008 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Mania Required Intervention 11/21/2007 77 Female 106 lb 2/1/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 1/25/2008 Belgium
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 2/6/2008 Belgium
Primary
Concomitant
Renal Failure Hospitalization 10/3/2007 68 Female 2/25/2008 France
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/1/2007 82 Male 2/26/2008 Sweden
Primary
Concomitant
Pharmaceutical Product Complaint Disability 8/1/2007 82 Female 144 lb 2/29/2008 United Kingdom
Primary
Secondary
Concomitant
Hypomania Other Serious 10/1/2007 77 Female 106 lb 3/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/2/2007 97 Female 3/12/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/2/2007 96 Female 3/19/2008 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Hospitalization 11/16/2007 93 Female 3/21/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/6/2008 66 Female 251 lb 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Cerebral Infarction Life Threatening 12/15/2007 Female 3/28/2008 Spain
Primary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Deafness Other Serious 9/2/2007 Female 121 lb 4/1/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/16/2007 93 Female 4/2/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 2/7/2008 86 Female 4/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization Male 4/3/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 2/7/2008 86 Female 4/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 1/3/2008 83 Female 4/8/2008 Physician Belgium
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/14/2008 Female 4/29/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data