Acetaminophen combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vision Blurred Hospitalization 8/9/2005 57 Male 272 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/30/2006 49 Male 148 lb 2/9/2006 France
Primary
Concomitant
Dyspnoea Hospitalization 2/21/2006 57 Male 190 lb 2/27/2006 Netherlands
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/21/2006 57 Male 190 lb 3/1/2006 Netherlands
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/19/2005 71 Male 157 lb 3/8/2006 Germany
Primary
Concomitant
Condition Aggravated Hospitalization 12/19/2005 71 Male 157 lb 3/17/2006 Other Health Professional Germany
Primary
Concomitant
Urosepsis Death 3/9/2006 70 Male 106 lb 5/3/2006 Physician Sweden
Primary
Concomitant
Dyspnoea Hospitalization Male 5/18/2006 Switzerland
Primary
Concomitant
Weight Decreased Hospitalization 1/30/2006 49 Male 148 lb 5/30/2006 France
Primary
Concomitant
Dyspnoea Hospitalization Male 151 lb 6/1/2006 Switzerland
Primary
Concomitant
Vomiting Hospitalization 7/13/2005 79 Female 179 lb 6/8/2006 Physician United States
Primary
Secondary
Concomitant
Vith Nerve Paralysis Life Threatening 5/10/2006 47 Female 136 lb 6/13/2006 Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2006 54 Male 164 lb 6/26/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/10/2006 47 Female 136 lb 6/27/2006 Australia
Primary
Concomitant
Confusional State Hospitalization 6/21/2006 65 Male 7/5/2006 France
Primary
Concomitant
Vomiting Hospitalization 5/10/2006 47 Female 136 lb 7/5/2006 Australia
Primary
Concomitant
Vomiting Hospitalization Female 137 lb 7/5/2006 Sweden
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 54 Male 164 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/20/2006 64 Male 99 lb 7/6/2006 France
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 6/21/2006 65 Male 7/10/2006 France
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 4/20/2006 64 Male 99 lb 7/18/2006 France
Primary
Concomitant
Vomiting Hospitalization 5/30/2006 58 Female 137 lb 7/20/2006 Sweden
Primary
Concomitant
Vomiting Hospitalization 5/30/2006 58 Female 137 lb 7/27/2006 Sweden
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 55 Male 163 lb 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 3/14/2006 55 Male 163 lb 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 6/13/2006 65 Male 8/7/2006 Physician France
Primary
Concomitant
Pneumonitis Hospitalization 7/20/2006 57 Male 174 lb 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 7/25/2006 71 Male 134 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 8/8/2006 73 Male 128 lb 8/21/2006 Physician Belgium
Primary
Concomitant
Pyrexia Other Serious 7/11/2006 46 Male 205 lb 8/24/2006 Australia
Primary
Concomitant
Pyrexia Other Serious 9/7/2005 45 Male 205 lb 8/29/2006 Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2006 55 Male 163 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 2/6/2006 61 Male 112 lb 10/2/2006 Physician France
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 4/26/2006 59 Male 10/9/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 2/6/2006 61 Male 112 lb 10/12/2006 Physician France
Primary
Concomitant
Cardiomyopathy Alcoholic Life Threatening 8/8/2006 73 Male 128 lb 10/24/2006 Physician Belgium
Primary
Concomitant
Cardiomyopathy Alcoholic Life Threatening 8/8/2006 73 Male 128 lb 10/25/2006 Physician Belgium
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 10/31/2006 Australia
Primary
Concomitant
Weight Decreased Hospitalization 12/19/2005 71 Male 157 lb 11/3/2006 Physician Germany
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 9/7/2005 45 Male 205 lb 11/16/2006 Australia
Primary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 3/24/2006 75 Male 163 lb 1/23/2007 Physician France
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 3/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 59 Male 157 lb 3/26/2007 Netherlands
Primary
Concomitant
Vomiting Hospitalization 4/1/2006 59 Male 157 lb 3/27/2007 Netherlands
Primary
Concomitant
Hyperhidrosis Hospitalization 2/25/2007 Male 146 lb 3/28/2007 Physician Korea, Republic Of
Primary
Concomitant
Hyperhidrosis Hospitalization 2/25/2007 Male 146 lb 3/29/2007 Physician Korea, Republic Of
Primary
Concomitant
Postoperative Wound Complication Required Intervention 4/1/2006 54 Male 288 lb 8/7/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 12/11/2006 51 Male 185 lb 5/10/2007 Physician Denmark
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5/1/2007 68 Female 62 lb 6/14/2007 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/25/2007 68 Female 62 lb 7/17/2007 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/20/2007 61 Male 187 lb 7/18/2007 Physician Spain
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 7/16/2007 58 Male 191 lb 7/18/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 48 Male 183 lb 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/14/2004 Female 8/20/2007 Pharmacist United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 4/20/2006 65 Male 99 lb 9/28/2007 Physician Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/26/2006 59 Male 10/8/2007 Physician Germany
Primary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 11/14/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 11/26/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 10/30/2007 62 Male 12/14/2007 Physician France
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 10/2/2007 63 Female 123 lb 12/20/2007 Physician Hong Kong
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/18/2007 70 Female 110 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/15/2008 66 Male 183 lb 3/11/2008 Physician Germany
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 3/31/2008 Consumer United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 3/17/2008 75 Male 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/1/2007 53 Male 161 lb 4/4/2008 Physician Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/15/2008 66 Male 183 lb 5/14/2008 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 3/17/2008 75 Male 5/14/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2007 68 Female 62 lb 5/15/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/9/2008 49 Female 143 lb 5/20/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 5/20/2008 Physician Germany
Primary
Secondary
Concomitant
Haemoptysis Other Serious 11/29/2007 69 Male 115 lb 5/30/2008 Physician France
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/7/2008 49 Female 143 lb 6/17/2008 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/5/2008 70 Male 181 lb 7/16/2008 Mexico
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/20/2007 70 Male 181 lb 7/31/2008 Mexico
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/21/2008 42 Female 128 lb 8/25/2008 United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/30/2008 85 Male 176 lb 8/25/2008 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/18/2007 70 Male 181 lb 9/18/2008 Mexico
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 11/29/2007 69 Male 115 lb 9/18/2008 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2006 59 Male 157 lb 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/3/2008 United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/29/2008 57 Male 10/7/2008 Germany
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/22/2008 59 Female 218 lb 10/9/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Other Serious 9/16/2008 60 Male 10/27/2008 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 10/18/2007 84 Female 10/30/2008 Physician Spain
Primary
Concomitant
Hyperkalaemia Other Serious 9/29/2008 57 Male 11/4/2008 Germany
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 11/18/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Other Serious 9/29/2008 57 Male 12/12/2008 Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 11/30/2006 61 Male 172 lb 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/29/2008 57 Male 1/22/2009 United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 8/19/2008 66 Male 3/19/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/5/2009 59 Male 165 lb 3/20/2009 Physician Germany
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 9/27/2008 66 Male 3/30/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/11/2009 43 Male 4/1/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/11/2009 43 Male 4/16/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Rash Hospitalization 4/1/2009 69 Male 4/20/2009 Netherlands
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/26/2009 66 Male 123 lb 4/23/2009 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 2/11/2009 43 Male 4/27/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Tetany Other Serious 2/21/2008 42 Female 108 lb 5/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Other Serious 7/16/2009 65 Male 234 lb 8/7/2009 Physician Canada
Primary
Concomitant
Ejection Fraction Decreased Other Serious 7/16/2009 65 Male 234 lb 9/30/2009 Physician Canada
Primary
Concomitant
Diverticulitis Hospitalization 4/18/2008 59 Male 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/11/2009 52 Female 93 lb 10/21/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/11/2009 52 Female 93 lb 10/26/2009 Physician United States
Primary
Concomitant
Pyrexia Life Threatening 3/27/2009 77 Male 187 lb 10/27/2009 Physician Canada
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/7/2009 75 Female 97 lb 11/2/2009 Physician Spain
Primary
Secondary
Concomitant
Troponin Increased Other Serious 12/13/2009 Female 173 lb 1/7/2010 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/28/2009 81 Male 141 lb 1/12/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/28/2009 81 Male 141 lb 1/28/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Pyrexia Other Serious 1/15/2010 Female 174 lb 2/2/2010 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 12/13/2009 Female 173 lb 2/9/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 1/15/2010 Female 174 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 12/12/2009 82 Male 3/30/2010 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Other Serious 12/13/2009 45 Female 173 lb 4/21/2010 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 12/13/2009 45 Female 173 lb 4/30/2010 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 11/29/2007 69 Male 115 lb 5/4/2010 Physician France
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/8/2010 69 Male 5/21/2010 Physician Canada
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 5/8/2010 69 Male 5/25/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/16/2010 41 Male 6/16/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 5/8/2010 69 Male 6/24/2010 Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 187 lb 7/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 187 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Fistula Hospitalization 1/28/2010 54 Female 101 lb 7/19/2010 Physician Korea, Republic Of
Primary
Concomitant
Pleural Effusion Other Serious 3/31/2010 69 Male 106 lb 8/3/2010 Physician France
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 3/18/2010 62 Female 7/29/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Tumour Compression Hospitalization 7/2/2010 54 Male 8/12/2010 Other Health Professional Netherlands
Primary
Concomitant
Ascites Hospitalization Male 128 lb 8/18/2010 Physician Singapore
Primary
Secondary
Concomitant
Intestinal Fistula Hospitalization 1/28/2010 54 Female 101 lb 8/26/2010 Physician Korea, Republic Of
Primary
Concomitant
Encephalopathy Other Serious 2/25/2010 72 Male 168 lb 8/27/2010 Physician United States
Primary
Concomitant
Ascites Hospitalization Male 128 lb 9/1/2010 Physician Singapore
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 12/12/2009 82 Male 9/15/2010
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 154 lb 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Other Serious 7/29/2010 61 Male 128 lb 9/29/2010 Physician Singapore
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/23/2010 69 Male 9/24/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 5/8/2010 69 Male 9/29/2010 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/23/2010 69 Male 11/17/2010 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Stomatitis Other Serious 3/3/2011 75 Female 82 lb Other Health Professional United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2010 69 Female 5/20/2011 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/15/2010 69 Female 9/2/2011 Physician United Kingdom
Primary
Concomitant
Confusional State Hospitalization 11/17/2009 58 Male 112 lb 11/29/2011 Physician France
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 2/15/2010 68 Male 203 lb 2/14/2012 Physician France
Primary
Concomitant
Generalised Oedema Death 2/15/2010 68 Male 203 lb 2/24/2012 Physician France
Primary
Concomitant

Drug Data