Acetaminophen combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 51 Female 2/8/2006 Canada
Primary
Secondary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Splenomegaly Hospitalization 9/30/2003 50 Female 129 lb 3/15/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 2/9/2006 53 Female 157 lb 3/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 1/5/2006 67 Male 191 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/5/2003 52 Female 5/11/2006 Canada
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/1/2006 36 Female 5/26/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/6/2006 54 Male 143 lb 5/31/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 10/6/2005 56 Male 140 lb 7/5/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/3/2006 85 Male 217 lb 7/18/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/30/2006 57 Male 149 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/3/2006 85 Male 217 lb 9/22/2006 Other Health Professional United States
Primary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Oedema Hospitalization 6/7/2006 58 Male 11/10/2006 United Kingdom
Primary
Concomitant
Vascular Bypass Graft Other Serious 7/21/2005 Male 216 lb 12/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/5/2007
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/8/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Other Serious 11/12/2006 Male 216 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 2/17/2004 Male 1/9/2007 Physician Italy
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 54 Male 1/11/2007 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/13/2003 Male 1/26/2007 Australia
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 2/14/2007 Male 180 lb 2/27/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Neonatal Hospitalization 7/3/2006 0 Female 2/26/2007 Belgium
Primary
Concomitant
Pyrexia Hospitalization Female 5/16/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/30/2007 Female 107 lb 5/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 10/22/2006 11 Female 75 lb 7/2/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Reaction 4/13/2003 Male 11/30/2007 Australia
Primary
Secondary
Concomitant
Neck Pain 10/12/2007 Female 128 lb 12/14/2007 United States
Primary
Concomitant
Stomatitis 10/31/2007 Female 130 lb 12/14/2007 United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 4/1/2007 Male 12/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 1/10/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Death 11/20/2007 Female 139 lb 2/4/2008 United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/19/2008 Male 133 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Hypersensitivity Death 11/20/2007 Female 139 lb 2/8/2008 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/13/2008 69 Male 2/20/2008 Physician Malaysia
Primary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 2/26/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/25/2007 Male 163 lb 2/29/2008 United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 2/13/2008 69 Male 3/10/2008 Physician Malaysia
Primary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Bronchiectasis Hospitalization 3/1/2006 36 Female 130 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Tachycardia Other Serious 2/13/2008 Male 165 lb 3/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/13/2008 Male 165 lb 4/29/2008 Consumer United States
Primary
Secondary
Concomitant
Tachypnoea Death 4/25/2008 Male 201 lb 4/28/2008 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 4/1/2007 Male 5/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cerebral Haematoma Hospitalization 8/10/2006 Female 5/13/2008 France
Primary
Concomitant
Ventricular Tachycardia Other Serious 11 Male 5/13/2008
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/13/2008 Sweden
Primary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/20/2008 Male 247 lb 6/12/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 60 Male 5/30/2008 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2008 Female 146 lb 6/17/2008 France
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/20/2008 Male 247 lb 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2008 Female 146 lb 7/8/2008 France
Primary
Concomitant
Cardiac Failure Life Threatening 8/3/2008 63 Male 8/8/2008 Sweden
Primary
Concomitant
Drug Toxicity Life Threatening 1/3/2006 58 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Maculo-papular Hospitalization 7/26/2008 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestinal Ulcer Haemorrhage Life Threatening 5/28/2008 59 Male 9/9/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/3/2008 59 Male 156 lb 9/10/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocolitis Infectious Hospitalization 5/21/2008 Female 126 lb 11/3/2008 France
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/20/2008 Male 247 lb 12/29/2008 Physician United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Serotonin Syndrome Hospitalization 9 Male 68 lb 1/23/2009
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Haemolysis Hospitalization 2/4/2009 Female 115 lb 4/21/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2008 55 Female 4/29/2009 Japan
Primary
Concomitant
Sepsis Other Serious 5/6/2009 Female 129 lb 6/19/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 6/23/2009 Physician Japan
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/6/2009 Female 129 lb 6/26/2009 United States
Primary
Concomitant
Hepatic Failure Death Female 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Malaise 8/18/2008 Female 142 lb 7/23/2009 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 10/9/2009 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Swollen Tongue Other Serious 1/19/2008 20 Male 174 lb 2/1/2010 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 74 2/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 2/4/2010 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 59 Female 2/26/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 85 Female 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 3/10/2010 Female 130 lb 3/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2010 Female 130 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 Female 118 lb 3/29/2010 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/1/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 37 Female 118 lb 4/1/2010 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/9/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/2/2008 47 Female 5/7/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 5/7/2010 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/28/2010 33 Male 99 lb 5/25/2010 Physician Japan
Primary
Concomitant
Peripheral Vascular Disorder Other Serious 5/15/2008 65 Male 6/9/2010 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 5/21/2010 89 Female 6/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 6/28/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Expired Drug Administered 2/12/2010 64 Female 210 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2008 13 Female 64 lb 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 74 Male 214 lb 7/1/2010 Consumer Canada
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/7/2010 Physician United States
Primary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data