Acetaminophen combined with Senna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Disability 2/22/2005 87 Male 169 lb 1/10/2006 Pharmacist United States
Primary
Concomitant
Eosinophilia 10/7/2005 65 207 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Eosinophilia 1/1/2005 36 224 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Pathological Fracture Hospitalization 12/15/2005 79 Male 135 lb 1/9/2006 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 10/22/2005 86 Female 223 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Disability 3/10/2005 87 Male 169 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 11/22/2005 73 Female 2/8/2006 United Kingdom
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Retinopathy Hypertensive Disability 5/19/2005 63 Female 114 lb 2/23/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/6/2005 92 Female 3/27/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Loss Of Consciousness Death 79 Male 4/6/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2001 70 Female 126 lb 4/14/2006 Physician Canada
Primary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 12/22/2005 Female United States
Primary
Concomitant
Rash Macular Hospitalization 1/1/2005 65 Female 4/28/2006 Pharmacist Singapore
Primary
Concomitant
Non-hodgkin's Lymphoma Death 78 Female 6/26/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 6/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Death 78 Female 7/6/2006 United Kingdom
Primary
Secondary
Granulocytopenia Required Intervention 10/18/2005 67 Male 202 lb 3/9/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/7/2005 64 Male 7/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Ratio Increased Other Serious 1/1/2006 77 Female 117 lb 8/1/2006 Consumer United States
Primary
Concomitant
Surgery Life Threatening 31 Male 8/7/2006 United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Death 7/23/2004 Female 143 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 11/1/2001 79 Male 8/3/2006 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious 2/5/2006 81 Female 8/14/2006 Denmark
Primary
Concomitant
Helicobacter Gastritis Required Intervention 70 Male 8/15/2006 Denmark
Primary
Concomitant
Haemorrhoids Hospitalization 8/4/2006 51 Female 171 lb 8/18/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/26/2006 82 Female 8/24/2006 United Kingdom
Primary
Concomitant
Blood Pressure Decreased Death 6/14/2006 Female 249 lb 8/21/2006 Pharmacist United States
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/5/2006 United States
Primary
Concomitant
Serum Sickness Other Serious 11/27/2003 51 Female 159 lb 9/22/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2005 67 Female 10/11/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased 8/23/2006 48 Female 132 lb 10/13/2006 Pharmacist United Kingdom
Primary
Concomitant
Rash Hospitalization 9/1/2006 59 Female 10/17/2006 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/26/2006 90 Male 10/10/2006 Other Health Professional Denmark
Primary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 9/6/2006 87 Female 10/18/2006 United Kingdom
Primary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/8/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/5/2006 96 Female 128 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 8/23/2006 85 Male 157 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/13/2006 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2000 50 Male 333 lb 11/16/2006 Physician United States
Primary
Concomitant
Oedema Hospitalization 6/7/2006 58 Male 11/10/2006 United Kingdom
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 4/14/2005 58 Female 11/23/2006 Physician New Zealand
Primary
Secondary
Concomitant
Skin Exfoliation 1/1/2004 75 Female 11/27/2006 Physician United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2006 79 Female 11/17/2006 United Kingdom
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Vomiting Other Serious 10/21/2006 85 Female 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious 9/21/2006 53 Female 11/27/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10/27/2006 54 Female 12/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 4/15/2006 Female 143 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Other Serious 10/30/2004 Male 254 lb 12/8/2006 Physician United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 67 Female 172 lb 12/8/2006 Pharmacist Canada
Primary
Concomitant
Weight Decreased Hospitalization 12/1/2004 52 Male 140 lb 12/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Life Threatening 7/6/2006 Male 187 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Skin Reaction 5/1/2006 21 Male 11/7/2006 Physician United States
Primary
Concomitant
Haematemesis Hospitalization 9/6/2006 87 Female 1/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Linear Iga Disease Death 9/1/2005 83 Male 187 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/13/2006 89 Male 121 lb 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Hospitalization 1/21/2007 26 Female 207 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/15/2006 Female 176 lb 3/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 3/5/2007 Female 114 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 2/24/2007 72 Male 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/5/2007 Female 114 lb 4/4/2007 Physician Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 3/19/2007 64 Female 4/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting 4/18/2006 40 Female 260 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 59 Female 4/6/2007 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 4/20/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Other Serious 12/5/2005 Male 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Paralysis Other Serious 87 Female 5/24/2007 Consumer Canada
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 3/5/2007 Female 114 lb 5/29/2007 Physician Canada
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 3/5/2007 Female 114 lb 6/15/2007 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/1/2005 81 Female 6/27/2007 United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 10/16/2006 Male 7/23/2007 Physician United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 7/6/2007 Female 7/23/2007 Physician United States
Primary
Concomitant
Ototoxicity Disability 1/1/2007 69 Male 110 lb 7/25/2007 United Kingdom
Primary
Concomitant
Thrombophlebitis Superficial Life Threatening 10/16/2006 Male 7/31/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 8/6/2007 Physician United States
Primary
Concomitant
Intestinal Perforation Hospitalization 7/29/2007 Female 8/7/2007 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/6/2007 Female 8/9/2007 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 7/29/2007 Female 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/5/2007 Female 114 lb 8/16/2007 Physician Canada
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 3/21/2006 76 Male 150 lb 8/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Hospitalization 10/16/2006 Male 8/20/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/14/2004 Female 8/20/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 3/5/2007 Female 114 lb 8/22/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Life Threatening 4/30/2007 Male 176 lb 8/24/2007 United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 12/28/2006 Female 105 lb 1/4/2007 Pharmacist United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 3/5/2007 Female 114 lb 8/31/2007 Physician Canada
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 7/29/2007 Female 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/30/2007 Male 176 lb 8/31/2007 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 4/30/2007 Male 176 lb 9/10/2007 United States
Primary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 9/17/2007 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/26/2007 62 Male 9/13/2007 United Kingdom
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/26/2007 62 Male 9/12/2007 Physician United Kingdom
Primary
Concomitant
Peritonitis Other Serious 8/16/2007 68 Female 154 lb 9/30/2007 Pharmacist United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 3/5/2007 Female 114 lb 10/11/2007 Physician Canada
Primary
Secondary
Concomitant
Lung Adenocarcinoma Metastatic Other Serious 5/10/2007 Female 117 lb 12/28/2007 South Africa
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 1/10/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 1/24/2008 Consumer United States
Primary
Concomitant
Death Death 12/16/2007 Male 1/29/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Retching 1/2/2008 77 Female 157 lb 2/17/2008 United States
Primary
Concomitant
Rash Erythematous Hospitalization 64 Male 178 lb 2/26/2008 Other Health Professional United States
Primary
Concomitant
Retching 1/2/2008 77 Female 157 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Bronchiectasis Life Threatening 10/1/2007 49 Female 203 lb 3/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 3/18/2008 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 3/21/2008 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 3/6/2008 43 Female 287 lb 3/26/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 5/1/2007 56 Female 3/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Hospitalization 3/6/2008 66 Female 251 lb 3/28/2008 Consumer United Kingdom
Primary
Concomitant
Rash Maculo-papular Death 1/8/1998 77 Male 132 lb 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 81 Female 110 lb 4/11/2008 Pharmacist United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/4/2008 66 Female 271 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/5/2008 Male 168 lb 5/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Poor Quality Sleep Other Serious 8/8/2007 Female 176 lb 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ovarian Cancer Hospitalization 3/5/2007 Female 114 lb 6/17/2008 Physician Canada
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 60 Male 176 lb 6/24/2008
Primary
Concomitant
Therapeutic Response Decreased Life Threatening Female 176 lb 7/29/2008 Other Health Professional Australia
Primary
Concomitant
Platelet Count Increased Hospitalization 6/19/2008 73 Female 128 lb 7/24/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/25/2006 70 183 lb 8/5/2008
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/24/2008 61 Male 7/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypokinesia Other Serious 6/3/2008 33 Male 134 lb 8/4/2008 United States
Primary
Secondary
Concomitant

Drug Data