Acetaminophen combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sinus Tachycardia Other Serious 12/7/2005 54 Male 201 lb 1/24/2006 Other Health Professional Canada
Primary
Concomitant
Suicidal Ideation Hospitalization 12/23/2005 40 Female 1/25/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/30/2005 85 Female 143 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Sinus Disorder Other Serious Male 150 lb 1/31/2006 United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 12/23/2005 40 Female 2/7/2006 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 12/23/2005 40 Female 2/28/2006 Physician Japan
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 12/23/2005 40 Female 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 22 Male 3/6/2006 United States
Primary
Secondary
Vomiting Other Serious 2/22/2006 85 Female 153 lb 2/22/2006 Pharmacist United States
Primary
Concomitant
Painful Respiration Hospitalization 1/1/2003 47 Female 141 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Suicide Attempt Hospitalization 22 Male 3/28/2006 Physician United States
Primary
Secondary
Concomitant
Gait Disturbance 1/18/2006 61 Male 4/7/2006 Pharmacist United States
Primary
Concomitant
Protein C Deficiency Hospitalization 1/1/2003 47 Female 141 lb 5/1/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 12/7/2005 54 Male 201 lb 5/5/2006 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 Male 209 lb 5/8/2006 Lawyer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 Male 209 lb 5/10/2006 Lawyer Canada
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/1990 Male 165 lb 6/21/2006 United States
Primary
Secondary
Concomitant
Rash Other Serious 5/13/2006 29 Male 176 lb 6/27/2006 Physician Spain
Primary
Concomitant
Mental Impairment Disability 6/27/2006 72 Female 130 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 5/8/2006 80 Male 166 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Mental Impairment Disability 6/27/2006 72 Female 130 lb 7/28/2006 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/1990 Male 165 lb 8/15/2006 United States
Primary
Secondary
Concomitant
Neurological Symptom Hospitalization 6/27/2006 72 Female 130 lb 9/8/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 8/9/2006 54 Female 170 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Death 2/15/2006 Male 235 lb United States
Primary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Vomiting Hospitalization 50 Male 10/20/2006 Physician India
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Drug Level Increased Hospitalization 10/15/2006 84 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Acute Hepatic Failure Other Serious 2/28/2007 Other Health Professional United States
Primary
Secondary
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Joint Dislocation Hospitalization 9/10/2003 86 lb 3/23/2007 Physician United Kingdom
Primary
Concomitant
Pyroglutamate Increased Hospitalization 50 Male 3/23/2007 Physician India
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 50 Male 5/8/2007 Other Health Professional India
Primary
Secondary
Concomitant
No Therapeutic Response Required Intervention 26 Male 179 lb 5/7/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Urinary Retention Other Serious 5/2/2007 48 Male 183 lb 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pathological Fracture Hospitalization 7/1/2007 Female 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/30/2007 Male 215 lb 10/25/2007 United States
Primary
Concomitant
Somnolence Other Serious 20 Male 11/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 11/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Tachycardia Life Threatening 12/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 33 Female 12/4/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 33 Female 12/17/2007 United Kingdom
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 22 Male 1/24/2008 Physician United Kingdom
Primary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/29/2008 78 Female 145 lb 2/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Other Serious 7/4/2007 2/14/2008 Physician Canada
Primary
Concomitant
Pustular Psoriasis Other Serious 11/25/2007 52 Male 2/22/2008 Other Health Professional Singapore
Primary
Secondary
Concomitant
Subdural Haemorrhage Other Serious 7/4/2007 3/28/2008 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 49 Male 5/5/2008 Consumer Canada
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 5/12/2008 60 Female 200 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Hospitalization 11/13/2007 61 Female 170 lb 7/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/16/2008 78 Female 7/9/2008 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Lymphadenopathy Hospitalization 8/31/2008 27 Male 9/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Life Threatening 9/8/2008 50 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3 Female 9/29/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Melaena Life Threatening 9/8/2008 50 Male 10/9/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Completed Suicide Death 55 Female 10/30/2008 Physician United States
Primary
Secondary
Status Epilepticus Required Intervention 3/13/2007 70 Female 11/7/2008 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/1/2005 48 Female 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 8/27/2008 65 Female 207 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 37 Male 176 lb 1/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 14 Female 3/5/2009 Netherlands
Primary
Secondary
Suicide Attempt Other Serious 14 Female 3/17/2009 Netherlands
Primary
Secondary
Pleural Effusion Other Serious 2/3/2009 25 Male 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 1 Female 5/1/2009 Physician Turkey
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 14 Female 5/7/2009 Germany
Primary
Secondary
Renal Failure Acute Hospitalization 1 Female 5/15/2009 Physician Turkey
Primary
Secondary
Concomitant
Embolic Cerebral Infarction Other Serious 6 Male 6/12/2009
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 12 Male 88 lb 7/1/2009 Consumer Canada
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/16/2009 50 Male 6/29/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 31 Female 9/7/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 9/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/2/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Required Intervention 4/1/2009 Male 161 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 3/13/2009 60 Male 10/13/2009 Other Health Professional Oman
Primary
Concomitant
Convulsion Other Serious 7/1/2009 24 Female 134 lb 10/26/2009 Other Health Professional Brazil
Primary
Concomitant
Status Asthmaticus Hospitalization 7/13/2009 Male 10/30/2009 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 8/22/2009 41 Male 1/13/2010 Physician United States
Primary
Secondary
Neutropenia Life Threatening 12/14/2009 Male 184 lb 1/20/2010 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 12/14/2009 Male 184 lb 2/9/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 30 Female 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting 7/1/2009 39 Female 115 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death 47 Male 300 lb 2/28/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 75 Female 198 lb 3/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Tonic Convulsion Hospitalization 12/23/2009 87 Female 3/25/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 1/12/2010 57 Female 3/24/2010 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Renal Failure Other Serious 3/1/2008 74 Male 6/15/2010 Lawyer United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 6/28/2010 Physician United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/7/2010 Physician United States
Primary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 11/5/2007 80 Male 150 lb 7/7/2010 Physician United States
Primary
Concomitant
Respiratory Tract Inflammation Other Serious 4/1/2010 64 Male 7/13/2010 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 22 Female 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Vertigo Other Serious 1/1/2008 35 Female 201 lb 8/9/2010 Physician United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2008 35 Female 201 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/1984 74 Male 8/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tinea Versicolour Hospitalization 3/28/2010 82 Male 8/13/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 8/13/2010 United States
Primary
Concomitant
Swelling Face Other Serious 2/1/2008 33 Female 198 lb 8/19/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 2/2/2008 36 Male 289 lb 9/8/2010 Lawyer United States
Primary
Concomitant
Swelling Face Other Serious 2/1/2008 33 Female 198 lb 10/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2010 46 Female 160 lb 10/13/2010 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 11/9/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 9 Female 73 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 12/15/2010 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 5/13/2010 55 Male 151 lb 11/29/2010 United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 38 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 55 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Injury Death 1/1/2009 55 Female 1/10/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/11/2011 Other Health Professional United States
Primary
Secondary
Death Death 38 Male 1/13/2011 Physician United States
Primary
Secondary
Dizziness Hospitalization 5/13/2010 55 Male 152 lb 1/4/2011 United States
Primary
Secondary
Concomitant
Medication Error Death 55 Female 1/14/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 Male 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/25/2011 Other Health Professional United States
Primary
Secondary
Hypotension Other Serious 1/1/1984 74 Male 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Accidental Exposure Death 55 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Drug Abuse Death 1/1/2009 55 Female 1/25/2011 Physician United States
Primary
Secondary
Poisoning Death 38 Male 1/28/2011 Other Health Professional Denmark
Primary
Secondary
Transaminases Increased Hospitalization 1/14/2011 34 Male 220 lb 2/11/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 38 Male 1/28/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 2/2/2011 United States
Primary
Secondary
Grand Mal Convulsion Hospitalization 1/22/2011 United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 1/22/2011 United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 55 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 8/2/2004 65 Female 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Completed Suicide Death 38 Male 3/7/2011 Other Health Professional United States
Primary
Secondary
Bradycardia Hospitalization Female 2/21/2011 Lawyer United States
Primary
Concomitant
Completed Suicide Death 38 Male 3/9/2011 Physician United States
Primary
Secondary
Ataxia Hospitalization 84 Male 3/14/2011 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 38 Male 3/30/2011 Physician United States
Primary
Secondary
Depressed Level Of Consciousness Other Serious 50 Female 4/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Metabolic Acidosis Hospitalization 5/1/2010 50 Female 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Depressed Level Of Consciousness Other Serious 50 Female 4/29/2011 Other Health Professional United Kingdom
Primary
Interacting
Depressed Level Of Consciousness Hospitalization 50 Female 4/26/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data