Acetaminophen combined with Naproxen Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 7/23/2001 24 Female 175 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Overdose Hospitalization 3/17/2006 46 Male 5/12/2006 France
Primary
Secondary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 5/25/2004 Male 166 lb 5/26/2006 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 7/5/2006 75 Female 7/19/2006 Physician Singapore
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/5/2006 75 Female 7/27/2006 Physician Singapore
Primary
Secondary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Scleroderma Other Serious 1/1/2001 58 Female 3/5/2007 Physician United States
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Scleroderma Other Serious 1/1/2001 58 Female 10/18/2007 Physician United States
Primary
Concomitant
Scleroderma Other Serious 1/1/2001 58 Female 10/25/2007 Physician United States
Primary
Concomitant
Scleroderma Other Serious 1/1/2001 58 Female 10/29/2007 Physician United States
Primary
Concomitant
Scleroderma Other Serious 1/1/2001 58 Female 2/18/2008 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2000 58 Female 134 lb 3/24/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2000 58 Female 134 lb 4/3/2008 Physician United States
Primary
Concomitant
Serum Ferritin Increased Hospitalization 2/20/2008 84 Male 4/3/2008 Sweden
Primary
Concomitant
Vomiting Hospitalization 5/24/2008 67 Male 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Juvenile Arthritis Other Serious 1/1/2008 16 Female 6/30/2008 United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/24/2008 61 Male 7/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/20/2008 14 Female 9/5/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Rash Macular 6/1/2008 Female 115 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased 8/20/2007 Female 120 lb 9/12/2008 Consumer United States
Primary
Concomitant
Pain 6/27/2008 Female 280 lb 9/12/2008 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/13/2008 Male 360 lb 10/8/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Female 150 lb 12/12/2008 Consumer United States
Primary
Concomitant
Uveitis 1/1/2007 Female 154 lb 12/12/2008 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 165 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious Male 12/18/2008 United States
Primary
Secondary
Upper Limb Fracture Other Serious 1/1/2003 64 Female 150 lb 1/21/2009 Other Health Professional United States
Primary
Concomitant
Death Death 1/1/2007 39 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Gastric Ulcer Perforation Life Threatening 3/2/2009 76 Female 168 lb 3/30/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 12/4/2003 25 Female 284 lb 4/17/2009 United States
Primary
Concomitant
Weight Decreased 8/20/2007 Female 120 lb 9/12/2009 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 12/1/2003 65 Female 190 lb 9/14/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 40 Male 3/19/2010 Physician United States
Primary
Secondary
Death Death 1/1/2008 47 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2008 23 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Lethargy Hospitalization 4/1/2009 60 Female 4/28/2010 United States
Primary
Secondary
Concomitant
Rheumatic Fever Other Serious 12/1/2008 48 Female 148 lb 6/16/2010 Consumer Brazil
Primary
Concomitant
Spondylolisthesis Hospitalization 4/14/2010 53 Female 179 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Ulcer Other Serious Female 135 lb 7/22/2010 Consumer United States
Primary
Secondary
Rash Maculo-papular Hospitalization 65 Male 9/1/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Rheumatic Fever Other Serious 1/1/2008 47 Female 154 lb 9/14/2010 Consumer Brazil
Primary
Concomitant
Pain Other Serious 1/1/2008 30 Female 118 lb 12/1/2010 United States
Primary
Concomitant
Rheumatoid Arthritis 12/21/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 12/23/2010 Consumer United States
Primary
Concomitant
Arthralgia 9/7/2010 Female 1/25/2011 Physician United States
Primary
Concomitant
Toxicity To Various Agents Death 57 Male 1/28/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 37 Female 1/28/2011 Other Health Professional United States
Primary
Secondary
Duodenal Ulcer Perforation Other Serious 41 Male 3/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 80 Female 3/16/2011 Pharmacist United States
Primary
Concomitant
Interacting
Drug Interaction Other Serious 80 Female 3/16/2011 Pharmacist United States
Primary
Concomitant
Interacting
Renal Impairment Death 80 Female 3/28/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Peptic Ulcer Haemorrhage Hospitalization 5/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Self Injurious Behaviour Other Serious 5/16/2011 23 Female 106 lb 5/27/2011 Other Health Professional Italy
Primary
Secondary
Metastases To Pelvis Other Serious Female 5/30/2011 United States
Primary
Secondary
Concomitant
Self Injurious Behaviour Other Serious 5/16/2011 23 Female 106 lb 6/1/2011 Physician Italy
Primary
Secondary
Self Injurious Behaviour Other Serious 5/16/2011 23 Female 106 lb 6/7/2011 Physician Italy
Primary
Secondary
Haematochezia Other Serious 23 Female 5/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/8/2011 83 Female 6/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 4/8/2011 83 Female 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Unevaluable Event Other Serious Female 6/29/2011 Consumer United States
Primary
Secondary
Nephritis Hospitalization 4/28/2011 36 Male 7/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Injury Other Serious 8/5/2004 51 Male 173 lb 7/8/2011 Lawyer United States
Primary
Concomitant
Asthma Other Serious 61 Female 7/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/27/2011 41 Female 7/15/2011 Other Health Professional France
Primary
Secondary
Rheumatoid Arthritis Other Serious 61 Female 7/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Night Sweats Disability 6/26/2011 55 Female 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Spinal Disorder Other Serious 1/1/2009 61 Female 7/22/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 6/17/2008 46 Female 179 lb 7/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 4/21/2011 61 Female 8/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Night Sweats Disability 6/26/2011 55 Female 7/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 4/5/2011 83 Female 7/29/2011 Physician Japan
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2009 61 Female 8/5/2011 United States
Primary
Concomitant
Conjunctivitis Infective Hospitalization 2/1/2011 69 Female 150 lb 8/26/2011 Consumer United States
Primary
Secondary
Concomitant
Chronic Respiratory Failure Hospitalization 5/27/2011 82 Male 132 lb 10/3/2011 Other Health Professional United States
Primary
Concomitant
Haematemesis Other Serious 9/22/2011 44 Female 137 lb 10/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lumbar Spinal Stenosis Other Serious 1/1/2009 61 Female 10/7/2011 Consumer United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Hospitalization 5/30/2009 40 Female 150 lb 10/12/2011 Physician United States
Primary
Concomitant
Periorbital Oedema Other Serious 1/1/1997 20 Female 10/1/2011 Other Health Professional Singapore
Primary
Secondary
Intervertebral Disc Protrusion Other Serious 7/1/2008 60 Female 139 lb 10/14/2011 Physician United States
Primary
Concomitant
Lip Swelling Other Serious 9/22/2011 50 Female 10/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Disability 6/12/2011 32 Female 11/1/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Multiple Sclerosis 8/1/2011 62 Female 141 lb 11/3/2011 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 9/1/2009 63 Female 150 lb 10/28/2011 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 6/12/2011 32 Female 11/4/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Blister Other Serious 10/19/2011 65 Female 136 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dehydration Hospitalization 5/27/2011 82 Male 132 lb 11/11/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Other Serious 9/4/2011 64 Female 168 lb 11/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2011 62 Female 141 lb 11/17/2011 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2011 62 Female 141 lb 11/23/2011 United States
Primary
Concomitant
Dyspnoea Hospitalization 5/27/2011 82 Male 129 lb 12/6/2011 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 1/1/2011 62 Female 141 lb 12/12/2011 United States
Primary
Concomitant
Injection Site Nodule Other Serious 8/1/2011 48 Female 12/12/2011 Consumer Brazil
Primary
Concomitant
Scapula Fracture Hospitalization 3/12/2004 66 Male 178 lb 12/15/2011 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/27/2011 82 Male 129 lb 12/16/2011 Other Health Professional United States
Primary
Concomitant
Blood Creatine Phosphokinase Mb Increased Other Serious 30 Female 12/16/2011 United States
Primary
Secondary
Immune Reconstitution Syndrome Other Serious 1/1/2011 62 Female 141 lb 12/21/2011 Physician United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2011 62 Female 141 lb 12/21/2011 Other Health Professional United States
Primary
Concomitant
Drug Hypersensitivity Hospitalization 8/1/2011 48 Female 12/22/2011 Consumer Brazil
Primary
Concomitant
Drug Hypersensitivity Other Serious 8/1/2011 48 Female 1/9/2012 Consumer Brazil
Primary
Concomitant
Toxicity To Various Agents Death 50 Female 1/11/2012 Physician United States
Primary
Secondary
Anhedonia Hospitalization 4/1/2009 38 Female 135 lb 1/13/2012 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/2/2012 72 Male 1/16/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 12/26/2010 47 Female 2/2/2012 Physician Germany
Primary
Concomitant
Fracture Other Serious 2/3/2012 Other Health Professional Denmark
Primary
Secondary
Biliary Dyskinesia Other Serious 1/1/2008 30 Female 119 lb 2/6/2012 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 1/1/2008 30 Female 119 lb 2/6/2012 Pharmacist United States
Primary
Concomitant
Carpal Tunnel Syndrome Other Serious Female 2/13/2012 Pharmacist United States
Primary
Secondary
Concomitant
Pain Hospitalization 4/1/2009 38 Female 135 lb 2/17/2012 Other Health Professional United States
Primary
Concomitant
Impaired Healing Other Serious 1/1/2007 69 Male 2/17/2012 Consumer United States
Primary
Concomitant
Autoimmune Disorder Hospitalization 8/1/2011 48 Female 3/5/2012 Consumer Brazil
Primary
Concomitant
Tendon Injury Hospitalization 1/1/2003 67 Female 218 lb 3/5/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/16/2012 75 Male 3/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Spasms Disability 6/1/2006 47 Female 3/14/2012 Consumer United States
Primary
Concomitant
Headache 4/27/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal Female 4/30/2012 Consumer United States
Primary
Secondary
Headache Other Serious 4/21/2012 50 Female 139 lb 5/2/2012 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 9/7/2008 53 Male 237 lb 5/2/2012 Consumer United States
Primary
Concomitant
Arthralgia 57 Female 245 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
No Adverse Event 5/7/2012 Consumer United States
Primary
Concomitant
Hepatic Haemorrhage Other Serious 5/8/2012 Consumer United States
Primary
Secondary
No Adverse Event 5/10/2012 Consumer United States
Primary
Concomitant
Headache 5/10/2012 Consumer United States
Primary
Concomitant
Dysmenorrhoea 5/14/2012 Consumer United States
Primary
Concomitant
No Adverse Event 5/14/2012 Consumer United States
Primary
Concomitant
Dysmenorrhoea 13 Female 5/14/2012 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 4/25/2012 12 Male 93 lb 5/14/2012 Consumer Brazil
Primary
Secondary
Concomitant
Pain 5/16/2012 Consumer United States
Primary
Concomitant
No Adverse Event 5/16/2012 2 Female 29 lb 5/22/2012 Consumer United States
Primary
Concomitant
Musculoskeletal Pain 5/25/2012 Consumer United States
Primary
Concomitant
Dysmenorrhoea 5/24/2012 Consumer United States
Primary
Concomitant
Headache 5/25/2012 Other Health Professional United States
Primary
Concomitant
No Adverse Event 5/23/2012 Consumer United States
Primary
Concomitant
Pain 5/21/2012 Consumer United States
Primary
Concomitant
Pain 5/24/2012 Consumer United States
Primary
Concomitant
Pain 5/24/2012 Consumer United States
Primary
Concomitant
Headache 5/28/2012 Consumer United States
Primary
Concomitant
Drug Ineffective 5/25/2012 Consumer United States
Primary
Concomitant
Lip Swelling Other Serious 5/8/2012 69 Male 168 lb 6/4/2012 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Respiratory Failure Hospitalization 5/27/2011 82 Male 129 lb 6/22/2012 Other Health Professional United States
Primary
Concomitant
Radiation Fibrosis - Lung Other Serious Female 7/6/2012 Physician United States
Primary
Secondary
Concomitant
Haematochezia Other Serious 23 Female 6/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2011 62 Female 141 lb 7/25/2012 Other Health Professional United States
Primary
Concomitant
Colonic Polyp Other Serious 8/1/2011 48 Female 7/31/2012 Consumer Brazil
Primary
Concomitant
Emphysema Hospitalization 5/27/2011 82 Male 129 lb 8/1/2012 Other Health Professional United States
Primary
Concomitant
Tachycardia 4/14/2004 13 Male 12/7/2012 Consumer Us
Primary
Secondary

Drug Data