Acetaminophen combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 11/1/2005 49 Male 1/31/2006 Physician Germany
Primary
Concomitant
Disease Progression Other Serious 5/1/2005 74 Male 2/8/2006 Consumer Sweden
Primary
Secondary
Concomitant
Dementia Other Serious 5/1/2005 74 Male 2/20/2006 Consumer Sweden
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/21/2006 United States
Primary
Concomitant
Urine Output Decreased Other Serious 12/2/2005 80 Female 3/15/2006 Sweden
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/23/2006 67 Male 188 lb 3/3/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2005 62 Male 220 lb 4/17/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 6/21/2005 65 Female 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 72 Female 256 lb 5/5/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 5/15/2005 82 Female 5/3/2006 Other Health Professional United States
Primary
Concomitant
Angioneurotic Oedema Other Serious 5/17/2005 75 Female 109 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 72 Female 256 lb 5/23/2006 United States
Primary
Concomitant
Urine Ketone Body Present Required Intervention 5/20/2003 28 Female 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Vasospasm Required Intervention 4/17/2006 45 Female 168 lb 6/6/2006 Physician United States
Primary
Concomitant
Retinal Haemorrhage Required Intervention 67 Male 6/23/2006 Physician United States
Primary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 2/15/2006 83 Male 230 lb 4/28/2006 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/18/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/26/2006 85 Male 200 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Insomnia 1/1/2006 80 Female 134 lb 7/12/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/27/2006 Denmark
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2006 36 Male 210 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 10/19/2006 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 5/6/2006 Female 11/10/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/10/2006 75 Male 231 lb 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Other Serious 7/15/2006 87 Male 191 lb 8/15/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/5/2006 72 Female 12/6/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Tinnitus Other Serious 11/9/2004 59 Male 141 lb 12/15/2006 Physician Germany
Primary
Secondary
Concomitant
Somnolence Hospitalization 2/1/2005 66 Male 12/14/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Hospitalization Female 12/21/2006 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 1/3/2007 United States
Primary
Concomitant
Somnolence Other Serious 38 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Blood Glucose Increased Life Threatening 7/6/2006 Male 187 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Required Intervention 8/15/2006 Female 160 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Complication Hospitalization 2/2/2007 80 Female 146 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Drug Level Increased Hospitalization 10/15/2006 84 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Reiter's Syndrome Hospitalization 4/5/2006 66 Male 2/8/2007 Sweden
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/7/2007 87 Female 130 lb 3/1/2007 Pharmacist Canada
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/16/2005 57 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Respiratory Distress Required Intervention 12/31/2006 49 Male 229 lb 3/6/2007 Pharmacist United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 11/22/2006 77 Male 3/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/3/2006 81 Female 3/15/2007 Consumer Canada
Primary
Concomitant
Oliguria Hospitalization 67 Female 3/27/2007 Other Health Professional Colombia
Primary
Concomitant
Metabolic Acidosis Hospitalization 40 Male 3/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 3/26/2007 Canada
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 10/13/2006 Female 121 lb 4/3/2007 Netherlands
Primary
Concomitant
Retinal Detachment Other Serious 10/31/2006 41 Male 157 lb 4/13/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 4/20/2007 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 10/31/2006 41 Male 157 lb 4/23/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 12/5/2005 Male 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Hospitalization 79 Male 4/23/2007 Consumer Sweden
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/1/2006 65 Male 241 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 4/1/2007 5/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Hospitalization 4/3/2006 79 Male 5/1/2007 Consumer Sweden
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/2/2006 42 Male 254 lb 5/9/2007 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 3/5/2007 78 Male 5/18/2007
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Fatigue Hospitalization 2/20/2007 Male 5/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 10/31/2006 41 Male 157 lb 5/25/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Tinnitus Hospitalization 3/1/2007 83 Male 6/7/2007 Canada
Primary
Concomitant
Retinal Detachment Other Serious 10/31/2006 41 Male 157 lb 6/13/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 7/7/2004 Male 236 lb 6/13/2007 Physician Germany
Primary
Concomitant
Retinal Detachment Other Serious 10/31/2006 41 Male 157 lb 6/20/2007 Physician Puerto Rico
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 2/28/2007 69 Male 6/19/2007 United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Open Wound Other Serious 5/1/2004 46 Male 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 4/1/2007 Male 181 lb 7/2/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/4/2007 Physician Germany
Primary
Secondary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 6/16/2006 Female 7/18/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 7/18/2007 60 Male 179 lb 7/19/2007 Consumer United States
Primary
Concomitant
Toxic Shock Syndrome Death 10/28/2004 84 Male 8/2/2007 Physician Japan
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 8/6/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Death 7/3/2007 68 Female 8/3/2007 Consumer Colombia
Primary
Concomitant
Pathological Fracture Hospitalization 7/1/2007 Female 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 7/26/2007 79 Male 225 lb 8/3/2007 Pharmacist United States
Primary
Concomitant
Methaemoglobinaemia Hospitalization 57 Male 8/20/2007
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/29/2007 69 Male 162 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 12/24/2006 Female 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 5/1/2007 90 Female 9/6/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Spinal Haematoma Hospitalization 6/28/2007 80 Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/22/2007 80 Male 180 lb 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Injection Site Irritation 6/1/2007 Female 165 lb 12/14/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection 9/13/2007 Female 147 lb 12/14/2007 Physician United States
Primary
Concomitant
Hepatic Failure Hospitalization 84 Female 12/19/2007 Other Health Professional Switzerland
Primary
Concomitant
Vomiting Hospitalization 11/3/2007 85 Female 126 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 67 Male 1/15/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/16/2005 89 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/16/2005 Female 2/26/2008 Consumer
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 44 Male 3/7/2008
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Serum Ferritin Increased Hospitalization 2/20/2008 84 Male 4/3/2008 Sweden
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/1/2008 86 Male 172 lb 4/13/2008 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2004 31 Male 4/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 11/1/2007 Female 115 lb 4/29/2008 Physician Germany
Primary
Concomitant
Chest Pain Life Threatening 5/8/2008 63 Male 5/14/2008 Sweden
Primary
Concomitant
Impaired Work Ability Life Threatening 2/1/2008 63 Male 128 lb 6/5/2008 Sweden
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 58 Female 159 lb 6/9/2008 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/13/2005 53 Female 5/8/2008 Lawyer United States
Primary
Concomitant
Polyneuropathy Other Serious 60 Male 5/30/2008 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 87 Female 7/7/2008 Consumer Norway
Primary
Secondary
Concomitant
Rash Other Serious 6/30/2008 50 Female 154 lb 7/10/2008 Physician Netherlands
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/31/2008 Female 198 lb 8/7/2008 Physician Colombia
Primary
Concomitant
Scab Hospitalization 8/15/1997 Female 172 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Onychoclasis 12/1/2007 Female 8/27/2008 Consumer United States
Primary
Concomitant
Pharyngeal Oedema 12/1/2007 Female 181 lb 8/27/2008 Consumer United States
Primary
Concomitant
Gastritis Hospitalization 6/21/2008 Female 159 lb 9/4/2008 Germany
Primary
Secondary
Concomitant
Yellow Skin Hospitalization 5/7/2006 Male 168 lb 9/9/2008 Belgium
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/3/2008 59 Male 156 lb 9/10/2008 United States
Primary
Concomitant
Urinary Retention 3/10/2008 Female 206 lb 9/12/2008 Consumer United States
Primary
Concomitant
Urticaria 7/1/2008 Female 200 lb 9/13/2008 United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 58 Female 159 lb 9/17/2008 Physician Germany
Primary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Ventricular Fibrillation Other Serious 3/28/2008 Male 154 lb 10/8/2008 Consumer Denmark
Primary
Secondary
Concomitant
Wheezing Hospitalization 75 Male 162 lb 10/14/2008 United States
Primary
Secondary
Concomitant
Subdural Haematoma Death Female 118 lb 11/14/2008 Consumer United States
Primary
Concomitant
Completed Suicide Death 43 Female 1/28/2009 Other Health Professional United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 2/3/2009 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Acute Hospitalization 1/26/2009 Male 205 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 35 Female 183 lb 4/23/2009 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/16/2008 64 Female 5/5/2009 Consumer Colombia
Primary
Concomitant
Renal Failure Acute Hospitalization 4/21/2009 67 Male 218 lb 5/22/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/16/2008 64 Female 5/20/2009 Consumer Colombia
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/16/2008 64 Female 5/20/2009 Consumer Colombia
Primary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Ventricular Arrhythmia Other Serious 2/1/2008 81 Male 161 lb 6/10/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/4/2009 74 Male 170 lb 6/12/2009 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Female 6/10/2009 Consumer United Kingdom
Primary
Concomitant
Hypotension Hospitalization 2/1/2009 59 Female 179 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2006 54 Male 335 lb 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 51 Female 300 lb 6/18/2009 United States
Primary
Concomitant
Medical Observation Hospitalization 6/4/2009 Male 6/18/2009 Physician United Kingdom
Primary
Concomitant

Drug Data