Acetaminophen combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/23/2001 24 Female 175 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
Wound Infection Hospitalization 7/5/2005 65 Male 2/1/2006 Physician Spain
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 11/25/2005 62 Male 2/1/2006 Physician Belgium
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2000 72 Female 150 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 12/1/2005 66 Male 2/21/2006 Physician Spain
Primary
Secondary
Concomitant
Liver Abscess Hospitalization 8/22/2005 53 Male 2/27/2006 Physician France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Sinus Tachycardia Death 38 Female 2/24/2006 Belgium
Primary
Secondary
Concomitant
Sudden Death Death 1/1/2005 38 Female 3/2/2006 Physician Belgium
Primary
Secondary
Concomitant
Sinus Tachycardia Death 38 Female 3/6/2006 Physician Belgium
Primary
Secondary
Concomitant
Vertigo Other Serious 3/1/2005 Female 154 lb 3/14/2006 Physician Belgium
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 5/10/2005 41 Male 3/23/2006 Physician France
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2000 72 Female 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/28/2005 50 Female 96 lb 3/17/2006 Other Health Professional Canada
Primary
Concomitant
Wheezing Hospitalization 3/6/2006 70 Female 3/15/2006 Colombia
Primary
Concomitant
Tuberculin Test Positive Other Serious 11/22/2005 Female 117 lb 4/3/2006 Physician Czech Republic
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Road Traffic Accident Hospitalization 1/1/2003 54 Male 196 lb 4/11/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Vascular Resistance Systemic Decreased Other Serious 53 Male 187 lb 4/14/2006 Other Health Professional Italy
Primary
Concomitant
Road Traffic Accident Hospitalization 1/1/2003 54 Male 196 lb 5/9/2006 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/15/2005 43 Male 5/10/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Face Oedema Life Threatening 3/5/2006 22 Female 99 lb 3/6/2006 United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/19/2005 66 Female 5/18/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vasospasm Required Intervention 4/17/2006 45 Female 168 lb 6/6/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/3/2006 Female 2/8/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2005 65 Male 6/19/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 3/26/2006 61 Female 6/13/2006 Other Health Professional United States
Primary
Secondary
Vascular Resistance Systemic Decreased Other Serious 1/15/2003 53 Male 187 lb 5/31/2006 Physician Italy
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2005 65 Male 6/26/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 6/28/2006 Physician France
Primary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 6/28/2006 Physician France
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 45 Male 176 lb 6/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatorenal Syndrome Hospitalization 1/5/2005 56 Female 6/29/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Kidney Transplant Rejection Hospitalization 1/5/2005 56 Female 7/5/2006 Physician France
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 5/9/2006 69 Male 7/14/2006 Physician France
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 Female 7/19/2006 Physician United States
Primary
Concomitant
Lung Disorder Hospitalization 3/23/2005 26 Male 7/25/2006 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 7/28/2006 Physician Belgium
Primary
Concomitant
Therapy Non-responder Hospitalization 7/23/2006 58 Male 313 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Required Intervention 4/17/2006 45 Female 168 lb 7/27/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/19/2006 56 Male 161 lb 7/31/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Other Serious 62 Male 8/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Other Serious 5/9/2006 52 Male 8/8/2006 Spain
Primary
Concomitant
Transplant Failure Required Intervention 5/12/2006 45 Female 159 lb 8/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/28/2005 50 Female 96 lb 7/31/2006 Other Health Professional Canada
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 12/5/2001 48 Female 161 lb 7/20/2006 Physician United Kingdom
Primary
Concomitant
Pyelonephritis Hospitalization 8/21/2005 47 Female 8/22/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/1/2005 55 Female 132 lb 9/7/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/29/2003 60 Female 9/5/2006 United States
Primary
Secondary
Concomitant
Skin Oedema Hospitalization 27 Male 9/7/2006 Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 5/28/2005 50 Female 96 lb 9/20/2006 Physician Canada
Primary
Concomitant
Liver Abscess Hospitalization 8/22/2005 53 Male 10/3/2006 Physician France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 10/4/2006 Physician Belgium
Primary
Concomitant
Staphylococcal Abscess Hospitalization 8/22/2005 53 Male 10/9/2006 Physician France
Primary
Secondary
Concomitant
Hepatitis C Hospitalization 4/24/2005 65 Male 10/11/2006 Physician France
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 5/18/2006 45 Male 176 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Phosphokinase Increased 45 Male 176 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/6/2006 45 Male 159 lb 11/6/2006 Physician France
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2006 Female 119 lb 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Kaposi's Sarcoma Other Serious 6/1/2006 44 Male 11/17/2006 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2006 Female 119 lb 11/20/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 8/4/2005 61 Male 11/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Other Serious 4/18/2005 59 Female 11/17/2006 Pharmacist United States
Primary
Concomitant
Suicide Attempt Life Threatening 12/6/2005 42 Female 12/5/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/17/2006 44 Male 179 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 3/31/2004 68 Female 1/17/2007 Spain
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 83 Female 2/27/2007 Physician Japan
Primary
Secondary
Concomitant
Epilepsy Hospitalization 11/27/2004 44 Female 3/30/2007 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/4/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/12/2006 33 Male 108 lb 7/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 1/1/2006 Female 7/20/2007 Physician Belgium
Primary
Concomitant
Throat Irritation Hospitalization 12/1/2005 Male 7/24/2007 Belgium
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Renal Artery Thrombosis Hospitalization 12/18/2003 44 Male 157 lb 2/28/2005 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/11/2007 58 Male 176 lb 9/20/2007 Pharmacist United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9 Male 11/21/2007 Sweden
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 11/19/2007 42 Female 248 lb 11/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Erythema Hospitalization 7/25/2007 65 Female 12/4/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization Male 1/22/2008 Physician Poland
Primary
Concomitant
Transplant Failure Other Serious 5/12/2006 45 Female 159 lb 2/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 20 Female 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 3/20/2008 Female 130 lb 3/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/21/2006 54 Male 134 lb 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 36 Female 227 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Stenotrophomonas Infection Other Serious 12/14/2006 79 Female 4/28/2008 Taiwan, Province Of China
Primary
Concomitant
Skin Necrosis Hospitalization Male 5/30/2008 Physician Poland
Primary
Concomitant
Weight Increased Hospitalization 2/12/2002 Male 168 lb 6/6/2008 Consumer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Weight Increased Hospitalization 2/1/2002 Male 168 lb 6/11/2008 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 12/24/2007 75 Male 6/9/2008 Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/7/2008 67 Male 159 lb 6/5/2008 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/12/2008 83 Male 174 lb 6/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 6/25/2008 Colombia
Primary
Secondary
Concomitant
Trigeminal Nerve Disorder Hospitalization 39 Female 6/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 3/25/2007 Male 193 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Death 3/1/2007 59 Male 193 lb 7/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Tuberculosis Other Serious 11/21/2001 Female 7/29/2008 Physician Spain
Primary
Secondary
Concomitant
Tuberculosis Other Serious 11/21/2001 Female 7/30/2008 Physician Spain
Primary
Secondary
Concomitant
Post Transplant Distal Limb Syndrome Other Serious 3/12/2008 57 Male 7/23/2008 Physician Japan
Primary
Concomitant
Sputum Discoloured Life Threatening 12/24/2007 75 Male 7/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 58 Female 8/20/2008 Other Health Professional
Primary
Concomitant
Therapeutic Aspiration Other Serious 13 Female 9/24/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 10/1/2008 Physician United States
Primary
Concomitant
Respiratory Distress Other Serious 1/1/2004 60 Female 10/2/2008 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Hospitalization 44 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Fungal Other Serious 1/1/2005 68 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 51 Male 10/3/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2006 60 Female 10/3/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 13 Female 10/9/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 11 Male 10/10/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Pyrexia Hospitalization 13 Female 10/13/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 11 Male 10/13/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/6/2008 25 Female 137 lb 10/20/2008 Brazil
Primary
Concomitant
Secondary Syphilis Hospitalization 34 Male 11/3/2008 Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 13 Female 11/7/2008 Physician Philippines
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 8/27/2008 65 Female 207 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 42 Female 1/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Adverse Event Other Serious 39 Female 1/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/12/2008 58 Female 1/29/2009 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 12/19/2008 60 Male 265 lb 5/8/2009 Physician United States
Primary
Concomitant
Respiratory Distress Death 3/5/2009 Male 5/20/2009 Physician France
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 27 Female 5/21/2009 Consumer United Kingdom
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 27 Female 6/5/2009 Consumer United Kingdom
Primary
Concomitant
Wheezing Other Serious 2/23/2008 1 Male 6/11/2009 Physician Brazil
Primary
Concomitant
Somnolence Other Serious 12/5/2008 Female 128 lb 6/19/2009 Other Health Professional France
Primary
Concomitant
Scleritis Other Serious 57 Male 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data