Acetaminophen combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 11/1/2005 49 Male 1/31/2006 Physician Germany
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 5/10/2005 Male 174 lb 2/13/2006 Physician Belgium
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/2/2006 70 Male 3/3/2006 United Kingdom
Primary
Concomitant
Dizziness Other Serious 9/13/2005 64 Male 209 lb 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 3/16/2006 74 Male 5/9/2006 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 5/3/2006 70 Male 5/18/2006 Physician France
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 5/3/2006 70 Male 6/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Leukopenia Required Intervention 9/13/2005 48 Male 1/13/2006 United States
Primary
Concomitant
Diabetes Mellitus 3/1/2005 38 Female 265 lb 8/1/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 4/10/2004 64 Male 8/2/2006 Pharmacist
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/3/2005 45 Female 280 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Local Swelling Hospitalization 6/27/2006 Male 8/14/2006 Physician Netherlands
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 11/4/2005 Male 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 3/20/2006 71 Female 9/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Local Swelling Hospitalization 6/27/2006 Male 10/5/2006 Physician Netherlands
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/6/2007
Primary
Concomitant
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/21/2007
Primary
Concomitant
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/15/2007 74 Female 157 lb 1/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/1/2008 United Kingdom
Primary
Concomitant
Urine Output Decreased Other Serious 70 Female 154 lb 3/9/2008 United Kingdom
Primary
Concomitant
Fatigue Other Serious 50 Female 268 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Intra-abdominal Haematoma Hospitalization 4/28/2008 77 Male 231 lb 6/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Postoperative Wound Infection Hospitalization 11/4/2005 Male 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Lethargy Disability 8/22/2008 66 Female 183 lb 10/14/2008 Pharmacist Australia
Primary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 10/22/2008 Consumer Switzerland
Primary
Concomitant
Renal Failure Chronic Hospitalization 7/1/2007 59 Female 10/17/2008 Norway
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 10/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Myositis Hospitalization 5/15/2008 64 Male 12/1/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Viral Myositis Hospitalization 5/15/2008 64 Male 12/3/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Lethargy Disability 8/22/2008 66 Female 183 lb 1/23/2009 Pharmacist Australia
Primary
Concomitant
Completed Suicide Death 43 Male 1/28/2009 Other Health Professional United States
Primary
Secondary
Brain Stem Infarction Hospitalization 9/10/2006 46 Female 3/17/2009 Korea, Republic Of
Primary
Concomitant
Ocular Neoplasm Hospitalization 1/1/2009 57 Male 4/17/2009 Physician Switzerland
Primary
Concomitant
Ocular Neoplasm Hospitalization 1/1/2009 57 Male 4/24/2009 Physician Switzerland
Primary
Concomitant
Rectal Cancer Other Serious 3/13/2009 Female 146 lb 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 6/4/2009 74 Male 170 lb 6/12/2009 Physician Australia
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2005 50 Male 260 lb 7/22/2009 United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 Male 172 lb 8/14/2009 Consumer United States
Primary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 203 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 9/1/2009 Physician United States
Primary
Secondary
Vision Blurred Disability 1/1/2009 65 Female 203 lb 9/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 8/31/2009 United Kingdom
Primary
Concomitant
Completed Suicide Death 9/4/2009 Physician United States
Primary
Secondary
Completed Suicide Death 9/4/2009 Physician United States
Primary
Secondary
Completed Suicide Death 50 Female 9/7/2009 Physician United States
Primary
Secondary
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 Male 172 lb 10/1/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/30/2009 41 Female 198 lb 10/13/2009 Other Health Professional Singapore
Primary
Concomitant
Staphylococcal Infection Other Serious 7/6/2009 Female 123 lb 10/14/2009 Physician Malaysia
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 10/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/29/2009 72 Female 11/12/2009 Other Health Professional France
Primary
Secondary
Concomitant
Rash Maculo-papular Death 10/7/2009 77 Female 11/25/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Sciatica Other Serious Female 3/9/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 Male 149 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/20/2003 Female 203 lb 3/19/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 Female 203 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Electrocardiogram Change Life Threatening 4/29/2010 70 Male 269 lb 5/19/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 5/19/2010 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/19/2008 64 Male 194 lb 5/20/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 66 Female 6/18/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 7/27/2010 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 5/22/2010 65 Female 7/30/2010 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious 12/1/2009 75 Female 146 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Wound Hospitalization 7/8/2010 79 Male 8/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wound Other Serious 1/1/2009 42 Female 201 lb 9/16/2010 Consumer United Kingdom
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 75 Male 172 lb 9/16/2010 Consumer United States
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 75 Male 172 lb 10/1/2009 Consumer United States
Primary
Concomitant
Rash Life Threatening 8/27/2010 70 Female 1/21/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Rash Life Threatening 8/27/2010 70 Female 1/26/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Hypotension Hospitalization 85 Male 2/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/16/2011 56 Female 2/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 1/1/2010 65 Female 2/21/2011 Pharmacist Australia
Primary
Concomitant
Completed Suicide Death 42 Male 3/3/2011 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 3/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 34 Female 3/7/2011 Other Health Professional United States
Primary
Secondary
Hepatitis Hospitalization 1/1/2010 65 Female 3/15/2011 Other Health Professional Australia
Primary
Concomitant
Drug Interaction Hospitalization 6/17/2009 85 Male 3/16/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 85 Male 3/17/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Dizziness Other Serious 1/1/2009 42 Female 196 lb 3/18/2011 Consumer United Kingdom
Primary
Concomitant
Myositis Hospitalization 5/27/2009 Female 6 lb 4/11/2011 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 4/19/2011 42 Female 138 lb 5/3/2011 United States
Primary
Secondary
Concomitant
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Confusional State Hospitalization 75 Female 5/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrophy Other Serious 7/18/2010 64 Female 7/5/2011 Physician Canada
Primary
Concomitant
Anaemia Hospitalization Male 7/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 7/26/2011 Japan
Primary
Concomitant
Skin Ulcer Disability 6/23/2009 78 Male 167 lb 8/25/2011 Physician United States
Primary
Secondary
Concomitant
Bradycardia Life Threatening 1/25/2011 66 Male 9/8/2011 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 56 9/22/2011 Other Health Professional United States
Primary
Secondary
Death Death 2/8/2011 78 Male 192 lb 9/22/2011 Physician Switzerland
Primary
Concomitant
Vomiting Other Serious 9/14/2011 73 Female 10/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Abdominal Discomfort Life Threatening 68 Male 10/4/2011 Japan
Primary
Concomitant
Somnolence Hospitalization 63 Male 10/7/2011 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 54 Female 172 lb 10/7/2011 Physician United Kingdom
Primary
Concomitant
Electrolyte Imbalance Hospitalization 6/9/2011 Female 187 lb 10/10/2011 Physician Denmark
Primary
Concomitant
Back Injury Other Serious Female 10/10/2011 Pharmacist Australia
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/7/2011 64 Male 195 lb 10/10/2011 Physician United States
Primary
Concomitant
Interacting
Vomiting Other Serious 1/17/2011 61 Female 135 lb 10/14/2011 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 4/13/2011 83 Male 10/17/2011 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/31/2011 74 Male 155 lb 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 68 Male 10/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 3/16/2011 62 Male 176 lb 10/18/2011 Denmark
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 12/1/2008 37 Female 10/18/2011 Consumer United States
Primary
Secondary
Concomitant
Bladder Transitional Cell Carcinoma Life Threatening 68 Male 10/18/2011 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 54 Male 10/17/2011 United Kingdom
Primary
Secondary
Concomitant
Appetite Disorder Other Serious 1/3/2008 70 Female 163 lb 10/28/2011 Consumer Brazil
Primary
Secondary
Concomitant
Bladder Transitional Cell Carcinoma Other Serious 1/1/2011 68 Male 11/30/2011 Czech Republic
Primary
Concomitant
Pneumonia Other Serious 10/25/2004 70 Male 212 lb 12/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 10/20/2011 73 Male 212 lb 12/16/2011 Physician United States
Primary
Secondary
Concomitant
Otitis Media Acute Hospitalization 1/1/1998 36 Female 172 lb 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 2/23/2010 21 Female 134 lb 12/22/2011 Lawyer United States
Primary
Concomitant
Completed Suicide Death 86 Female 12/22/2011 Physician United States
Primary
Secondary
Chronic Sinusitis Hospitalization 1/1/1998 36 Female 172 lb 12/29/2011 Consumer United States
Primary
Secondary
Concomitant
Phlebitis Other Serious 11/22/2011 53 Female 176 lb 12/29/2011 Physician France
Primary
Concomitant
Impaired Gastric Emptying Other Serious 1/1/1998 36 Female 172 lb 1/1/2012 Physician United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 10/1/2011 70 Female 1/2/2012 Physician Spain
Primary
Secondary
Concomitant
Exostosis Other Serious 1/1/1998 36 Female 172 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization 8/20/2011 61 Male 203 lb 1/6/2012 Physician France
Primary
Secondary
Concomitant
Anaemia Haemolytic Autoimmune Life Threatening 11/10/2011 80 Male 1/5/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2010 29 Female 1/10/2012 Physician United States
Primary
Secondary
Poisoning Death 1/1/2010 29 Female 1/11/2012 Physician United States
Primary
Secondary
Poisoning Death 1/1/2010 86 Female 1/11/2012 Physician United States
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 55 Female 240 lb 1/18/2012 Pharmacist France
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 83 Male 265 lb 1/19/2012 Other Health Professional United Kingdom
Primary
Concomitant
Lactic Acidosis Death 81 Female 1/16/2012 Other Health Professional Denmark
Primary
Concomitant
Failure To Thrive Hospitalization 11/26/2011 69 Female 144 lb 2/10/2012 Physician United States
Primary
Secondary
Concomitant
Haemodynamic Instability Life Threatening 2/9/2012 65 Female 3/2/2012 Physician Denmark
Primary
Secondary
Concomitant
Malaise Disability 2/13/2012 75 Female 154 lb 3/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Tremor 2/8/2012 90 Female 160 lb 3/13/2012 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 2/28/2012 71 Female 176 lb 3/19/2012 Other Health Professional Canada
Primary
Concomitant
Diarrhoea Hospitalization 7/13/2011 65 Female 3/19/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization 78 Male 186 lb 3/19/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 1/1/2012 69 Female 273 lb 3/20/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vision Blurred Disability 64 Female 185 lb 6/1/2012 Consumer Canada
Primary
Concomitant
Continuous Haemodiafiltration Death 81 Female 6/1/2012 Other Health Professional Denmark
Primary
Concomitant
Tardive Dyskinesia Hospitalization 1/1/2010 71 Female 6/29/2012 Other Health Professional France
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 11/17/2011 85 Female 6/25/2012 Other Health Professional France
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 1/1/2010 71 Female 7/5/2012 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data