Acetaminophen combined with Melphalan Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Bearing Difficulty Hospitalization 8/3/2009 79 Male 151 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/4/2007 Male 106 lb 9/10/2009 Poland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/3/2009 79 Male 151 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 Female 181 lb 3/24/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 3/14/2010 67 Male 203 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 4/9/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 4/30/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 2/6/2003 66 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 5/18/2010 84 Female 128 lb 6/18/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 5/26/2010 86 Male 184 lb 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 5/26/2010 86 Male 184 lb 6/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/22/2005 80 Female 181 lb 7/5/2010 United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 5/26/2010 86 Male 184 lb 7/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 7/7/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Cataract Operation Hospitalization 5/24/2010 67 Male 190 lb 9/14/2010 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/24/2010 77 Female 143 lb 9/15/2010 Physician Portugal
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/23/2010 69 Male 174 lb 9/17/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 9/9/2010 80 Female 134 lb 9/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/22/2005 80 Female 156 lb 9/30/2010 United States
Primary
Concomitant
Lung Disorder Hospitalization 8/23/2010 74 Male 181 lb 10/11/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/22/2005 80 Female 156 lb 10/12/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 8/23/2010 74 Male 181 lb 10/19/2010 Physician France
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2007 10/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 2/23/2005 47 Male 190 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 9/9/2010 80 Female 134 lb 11/22/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2009 54 Male 152 lb 11/23/2010 Consumer Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 3/1/2009 54 Male 152 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/18/2011 72 Male 3/17/2011 Pharmacist Portugal
Primary
Concomitant
Basal Cell Carcinoma Other Serious Male 3/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 10/20/2003 93 Female 126 lb 4/15/2011 Physician United States
Primary
Concomitant
Erythema Hospitalization 5/23/2008 82 Male 148 lb 5/10/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Platelet Count Increased Hospitalization 5/23/2008 82 Male 148 lb 5/10/2011 Physician Sweden
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 3/1/2011 64 Female 5/11/2011 Pharmacist United States
Primary
Concomitant
Paraesthesia Other Serious Female 291 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea 4/13/2011 81 Male 5/16/2011 Consumer United States
Primary
Concomitant
Lower Limb Fracture Other Serious 6/29/2006 82 Female 5/16/2011 Other Health Professional United States
Primary
Concomitant
Bone Lesion Other Serious 12/16/2005 61 Male 136 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 4/1/2011 63 Male 5/20/2011 Netherlands
Primary
Concomitant
Constipation Other Serious 1/27/2007 70 Female 5/20/2011 United States
Primary
Concomitant
Nervousness Other Serious 48 Female 250 lb 5/20/2011 Physician United States
Primary
Concomitant
Arrhythmia Supraventricular Hospitalization 4/22/2011 55 Female 218 lb 5/20/2011 Physician United States
Primary
Concomitant
Premature Delivery Hospitalization 3/1/2010 25 Female 112 lb 5/20/2011 Other Health Professional United States
Primary
Concomitant
Multiple Myeloma Hospitalization 10/4/2010 75 Male 132 lb 6/1/2011 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/26/2010 6/3/2011 Physician France
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 4/9/2011 77 Male 110 lb 6/8/2011 Physician France
Primary
Secondary
Concomitant
Oesophageal Squamous Cell Carcinoma Other Serious 1/4/2011 74 Male 181 lb 6/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 6/8/2011 72 Male 6/23/2011 Physician Sweden
Primary
Secondary
Concomitant
Oesophageal Squamous Cell Carcinoma Death 1/4/2011 74 Male 181 lb 6/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/4/2010 6/30/2011 Consumer France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/10/2011 35 Male 317 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 10/4/2010 75 Male 132 lb 6/30/2011 Physician France
Primary
Secondary
Concomitant
Dizziness Hospitalization 6/8/2011 72 Male 190 lb 7/6/2011 Physician Sweden
Primary
Secondary
Concomitant
Abscess Bacterial Hospitalization 11/25/2009 61 Male 141 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 6/8/2011 72 Male 190 lb 7/29/2011 Physician Sweden
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 1/26/2011 2 Male 27 lb 7/26/2011 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2009 54 Male 152 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Acidosis Hyperchloraemic Hospitalization 12/16/2005 61 Male 136 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Gastroenteritis Other Serious 2/11/2009 54 Male 152 lb 8/11/2011 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious Male 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 6/22/2005 80 Female 156 lb 9/16/2011 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Death 5/1/2011 70 Female 339 lb 9/19/2011 Physician United States
Primary
Concomitant
Performance Status Decreased Life Threatening 10/4/2010 75 Male 132 lb 9/26/2011 Physician France
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 10/1/2010 75 Male 132 lb 9/28/2011 Other Health Professional France
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 10/26/2010 9/29/2011 Consumer France
Primary
Secondary
Concomitant
Sepsis Other Serious 2/23/2005 47 Male 190 lb 10/10/2011 Physician United States
Primary
Secondary
Concomitant
Arthritis Death 6/22/2005 80 Female 156 lb 10/12/2011 Lawyer United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 9/1/2003 46 Male 130 lb 11/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Rectocele Hospitalization 1/1/2002 56 Female 195 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious Male 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Synovial Rupture Hospitalization 9/1/2003 46 Male 130 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Obesity Other Serious 1/1/2002 56 Female 195 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious Male 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Erectile Dysfunction Hospitalization 9/1/2003 46 Male 130 lb 11/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Abscess Bacterial Hospitalization 11/25/2009 61 Male 141 lb 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 8/20/2011 61 Male 203 lb 11/22/2011 Physician France
Primary
Secondary
Concomitant
Hydrocephalus Other Serious Male 11/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 8/20/2011 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2003 77 Female 11/28/2011 United States
Primary
Secondary
Concomitant
Cervical Spinal Stenosis Other Serious 9/1/2003 46 Male 130 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Cataract Hospitalization 11/3/2011 69 Male 185 lb 11/17/2011 Physician France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 12/14/2011 Physician Japan
Primary
Concomitant
Acute Leukaemia Hospitalization 11/3/2011 69 Male 185 lb 12/14/2011 Physician France
Primary
Secondary
Concomitant
Diarrhoea Other Serious Male 12/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Sarcoidosis Other Serious Male 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/5/2011 68 Female 88 lb 12/23/2011 Physician Japan
Primary
Concomitant
Prostatomegaly Other Serious 9/7/2011 74 Male 12/28/2011 Physician United States
Primary
Concomitant
Balance Disorder Other Serious Male 12/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 9/1/2003 46 Male 130 lb 1/2/2012 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious Female 1/3/2012 Physician United States
Primary
Secondary
Concomitant
Back Pain Other Serious Female 1/5/2012 Lawyer United States
Primary
Concomitant
Lacunar Infarction Hospitalization Female 1/13/2012 Physician United States
Primary
Concomitant
Dermoid Cyst Death 12/27/2011 85 Female 1/17/2012 Lawyer United States
Primary
Secondary
Concomitant
Chondrocalcinosis Hospitalization 8/17/2011 1/19/2012 Consumer United States
Primary
Secondary
Concomitant
Acute Leukaemia Death 11/3/2011 69 Male 185 lb 1/19/2012 Physician France
Primary
Secondary
Concomitant
Melaena Other Serious 1/1/2004 64 Female 195 lb 1/31/2012 Physician United States
Primary
Secondary
Concomitant
Chondrocalcinosis Death 12/27/2011 85 Female 1/31/2012 Lawyer United States
Primary
Secondary
Concomitant
Prostatomegaly Disability 9/7/2011 74 Male 1/31/2012 Physician United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 9/1/2003 46 Male 130 lb 2/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Cerebral Ventricle Dilatation Other Serious Male 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious Female 2/6/2012 Physician United States
Primary
Concomitant
Enterococcal Bacteraemia Hospitalization 12/1/2011 65 Female 260 lb 2/7/2012 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 2/7/2012 Physician Japan
Primary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Pain Hospitalization 7/1/2011 51 Male 2/13/2012 Consumer Brazil
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/13/2012 74 Male 242 lb 2/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 11/3/2011 69 Male 185 lb 2/21/2012 Physician France
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/25/2011 60 Female 137 lb 2/29/2012 France
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 61 Male 264 lb 3/1/2012 Lawyer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 1/1/2003 77 Female 3/6/2012 Physician United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 9/1/2003 46 Male 130 lb 3/6/2012 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 2/10/2012 7 57 lb 3/12/2012 Other Health Professional France
Primary
Concomitant
Drug Ineffective Hospitalization 7/1/2011 51 Male 3/21/2012 Consumer Brazil
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/13/2012 74 Male 242 lb 3/21/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/23/2010 69 Male 174 lb 3/23/2012 Physician Belgium
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 1/13/2012 74 Male 242 lb 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/10/2012 7 57 lb 3/27/2012 Other Health Professional France
Primary
Concomitant
Drug Ineffective Other Serious 11/10/2010 55 Male 3/29/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 8/5/2011 68 Female 88 lb 3/30/2012 Physician Japan
Primary
Concomitant
Mastication Disorder Other Serious Male 4/6/2012 Lawyer United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 61 Male 264 lb 4/11/2012 Consumer United States
Primary
Secondary
Concomitant
Influenza Hospitalization 7/1/2011 51 Male 4/24/2012 Consumer Brazil
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 9/2/2011 76 Female 4/30/2012 Physician Portugal
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 1/13/2012 74 Male 239 lb 5/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/1/2003 46 Male 130 lb 5/10/2012 Lawyer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/10/2011 91 Female 5/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 1/13/2012 74 Male 5/17/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/2/2011 76 Female 5/18/2012 Physician Portugal
Primary
Secondary
Concomitant
Duodenal Stenosis Hospitalization 10/25/2010 68 Male 148 lb 6/5/2012 Physician Netherlands
Primary
Secondary
Concomitant
Asthma Other Serious 1/1/2004 64 Female 195 lb 6/7/2012 Consumer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/10/2011 91 Female 313 lb 6/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Antithrombin Iii Decreased Hospitalization 9/22/2011 20 Female 106 lb 6/8/2012 Physician Japan
Primary
Concomitant
Refractory Cytopenia With Multilineage Dysplasia Other Serious 2/7/2012 79 Female 6/11/2012 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/25/2012 73 Female 6/12/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/20/2011 58 Male 189 lb 6/18/2012 Physician Spain
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2004 64 Female 195 lb 6/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 1/13/2012 74 Male 239 lb 6/25/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 11/10/2010 55 Male 7/4/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization Female 7/4/2012 Other Health Professional United States
Primary
Concomitant
Anaemia Hospitalization 1/25/2012 73 Male 7/5/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant
Multiple Myeloma Other Serious 10/10/2010 55 Male 7/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteomyelitis Disability 9/27/2010 71 Male 7/13/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Cerebral Ischaemia Death 12/27/2011 85 Female 7/16/2012 Consumer United States
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 1/25/2012 73 Male 7/17/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant

Drug Data