Acetaminophen combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 4/4/2005 47 Male 205 lb 1/31/2006 Physician Japan
Primary
Secondary
Concomitant
Surgery Hospitalization 12/1/2005 77 Female 2/16/2006 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/8/2005 34 Male 136 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/9/2006 68 Male 7/17/2006 Physician France
Primary
Concomitant
Infusion Related Reaction Other Serious 5/24/2006 Female 115 lb 8/16/2006 Physician Japan
Primary
Concomitant
Myoglobin Blood Increased Other Serious 2/20/2007 74 Female 3/13/2007 Physician Japan
Primary
Concomitant
Myoglobin Blood Increased Other Serious 2/20/2007 74 Female 3/19/2007 Physician Japan
Primary
Concomitant
Myoglobin Blood Increased Other Serious 2/20/2007 74 Female 3/23/2007 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 1/22/2007 70 Female 4/4/2007 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 4/16/2007 6 Female 4/27/2007 Pharmacist Japan
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 5/3/2007 Pharmacist Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/22/2007 Female 6/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 8/7/2007 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 9/18/2007 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 7/14/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/16/2006 Male 146 lb 8/22/2008 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 10/19/2007 31 Female 10/10/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/9/2007 Female 132 lb 11/5/2008 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 10/19/2007 31 Female 12/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/16/2005 Male 12/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Delirium Life Threatening 2/17/2009 39 Female 163 lb 3/23/2009 Physician Japan
Primary
Concomitant
Delirium Life Threatening 2/17/2009 Female 163 lb 5/20/2009 Physician Japan
Primary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 Female 99 lb 12/1/2009 Physician Japan
Primary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 Female 99 lb 12/11/2009 Physician Japan
Primary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 Female 99 lb 1/5/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 11/25/2008 70 Female 73 lb 3/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 Female 99 lb 3/30/2010 Physician Japan
Primary
Concomitant
Pneumonia Fungal Life Threatening 3/1/2010 85 Female 110 lb 4/28/2010 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 9/21/2009 72 Male 139 lb 5/21/2010 Physician Japan
Primary
Concomitant
Pneumonia Fungal Life Threatening 3/1/2010 85 Female 110 lb 5/19/2010 Physician Japan
Primary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 55 Female 99 lb 5/28/2010 Physician Japan
Primary
Concomitant
Thyroid Cancer Life Threatening 8/29/2007 55 Female 99 lb 5/28/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 8/15/2010 54 Male 9/20/2010 Pharmacist Japan
Primary
Concomitant
Malaise Other Serious 8/30/2010 54 Male 10/5/2010 Pharmacist Japan
Primary
Concomitant
Malaise Other Serious 8/30/2010 54 Male 10/25/2010 Pharmacist Japan
Primary
Concomitant
Pancytopenia Hospitalization 10/12/2010 65 Female 10/29/2010 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Hospitalization 10/12/2010 65 Female 11/3/2010 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/1/2010 55 Male 11/16/2010 Other Health Professional Japan
Primary
Concomitant
Immune System Disorder Other Serious 3/10/2011 90 Female 85 lb 5/26/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Death 8/21/2010 48 Female 95 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2011 77 Male 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 6/8/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/8/2011 83 Female 6/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/3/2010 58 Male 6/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/3/2009 60 Female 121 lb 6/15/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 3/18/2011 71 Male 6/28/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/11/2011 77 Male 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 7/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/23/2011 63 Female 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 3/18/2011 71 Male 7/12/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/15/2011 62 Male 126 lb 7/12/2011 Physician Japan
Primary
Concomitant
Fall Other Serious 4/26/2011 56 Male 7/12/2011 Pharmacist Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/1/2011 64 Male 108 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Death 3/18/2011 71 Male 7/21/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/2/2010 24 Female 7/25/2011 Physician Japan
Primary
Concomitant
Fall Other Serious 4/26/2011 56 Male 7/28/2011 Pharmacist Japan
Primary
Concomitant
Benign Prostatic Hyperplasia Death 3/5/2009 85 Male 108 lb 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 4/23/2011 56 Male 8/12/2011 Pharmacist Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/17/2011 68 Female 110 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Incorrect Dose Administered Other Serious 4/23/2011 56 Male 8/29/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/13/2010 65 Female 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Death 8/21/2010 48 Female 95 lb 9/1/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/5/2009 85 Male 108 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Engraftment Syndrome Other Serious 3/15/2011 49 Male 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/11/2011 61 Male 9/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Effect Decreased 8/24/2011 54 Male 9/14/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 6/17/2011 68 Female 110 lb 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 6/15/2011 62 Male 126 lb 9/20/2011 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Disability 6/6/2011 13 Female 88 lb 9/20/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 4/2/2008 55 Female 119 lb 9/28/2011 Physician Japan
Primary
Concomitant
Respiratory Depression Other Serious 6/17/2011 79 Female 101 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Life Threatening 10/3/2011 Male 10/13/2011 Physician Japan
Primary
Concomitant
Death Death 10/3/2011 Male 10/18/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/16/2010 69 Female 90 lb 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 10/4/2011 43 Male 11/3/2011 Physician Japan
Primary
Concomitant
Gastric Ulcer Other Serious 10/14/2011 72 Male 11/8/2011 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Death 6/6/2011 13 Female 88 lb 11/8/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 4/2/2008 55 Female 119 lb 11/18/2011 Physician Japan
Primary
Concomitant
Foot Amputation Other Serious 8/1/2011 72 Male 11/22/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Death 5/19/2011 83 Male 132 lb 11/28/2011 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/6/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Lymphocyte Stimulation Test Positive Hospitalization 8/27/2011 13 Female 12/6/2011 Physician Japan
Primary
Secondary
Concomitant
Ileus Other Serious 9/14/2009 41 Female 90 lb 12/14/2011 Physician Japan
Primary
Concomitant
Nausea Hospitalization 8/27/2011 13 Female 117 lb 12/16/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/19/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pain Other Serious Male 12/19/2011 Physician Japan
Primary
Concomitant
Corneal Erosion Hospitalization 9/6/2011 36 Female 12/20/2011 Physician Japan
Primary
Concomitant
Hypersensitivity Hospitalization 8/1/2008 54 Female 154 lb 12/20/2011 Consumer Japan
Primary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Acidosis Other Serious 12/17/2009 63 Male 110 lb 1/10/2012 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 5/1/2011 64 Male 108 lb 1/13/2012 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/22/2011 58 Female 77 lb 2/2/2012 Physician Japan
Primary
Concomitant
Skin Ulcer Death 1/1/2011 68 Male 130 lb 2/13/2012 Other Health Professional Japan
Primary
Concomitant
Meningitis Hospitalization 1/23/2012 15 Male 2/15/2012 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 5/19/2011 83 Male 132 lb 2/16/2012 Physician Japan
Primary
Concomitant
Pain Hospitalization 1/16/2012 60 Female 90 lb 2/17/2012 Physician Japan
Primary
Concomitant
Death Death 12/10/2011 78 Male 113 lb 2/24/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2011 63 Male 132 lb 2/24/2012 Physician Japan
Primary
Secondary
Concomitant
Abnormal Behaviour Hospitalization 1/29/2011 27 Male 139 lb 2/27/2012 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 2/11/2012 66 Male 148 lb 3/5/2012 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/11/2012 66 Male 148 lb 3/8/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Cor Pulmonale Death 12/7/2011 78 Male 113 lb 3/11/2012 Physician Japan
Primary
Concomitant
Cheilitis Hospitalization 12/21/2011 44 Female 148 lb 3/22/2012 Physician Japan
Primary
Concomitant
Lung Disorder Other Serious 9/29/2010 69 Male 137 lb 3/27/2012 Consumer Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2012 59 Male 4/3/2012 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 8/27/2011 13 Female 117 lb 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 2/11/2012 66 Male 148 lb 4/4/2012 Physician Japan
Primary
Secondary
Concomitant
Amputation Other Serious 8/1/2011 72 Male 4/5/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2012 66 Male 148 lb 4/5/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 8/21/2010 48 Female 95 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Other Serious 5/18/2011 75 Female 86 lb 4/9/2012 Other Health Professional Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 3/15/2012 72 Male 150 lb 4/10/2012 Physician Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 10/14/2011 72 Male 4/18/2012 Physician Japan
Primary
Secondary
Concomitant
Dehydration Other Serious 3/15/2012 59 Male 141 lb 4/13/2012 Physician Japan
Primary
Secondary
Concomitant
Skin Degenerative Disorder Hospitalization 12/21/2011 44 Female 148 lb 4/19/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 2/22/2012 66 Male 4/20/2012 Japan
Primary
Concomitant
Rectal Ulcer Haemorrhage Death 11/4/2011 45 Female 220 lb 4/20/2012 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 2/11/2012 66 Male 148 lb 4/24/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/11/2012 66 Male 148 lb 4/25/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 70 Female 5/4/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Hallucination, Auditory Other Serious Female 5/9/2012 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 70 Female 5/16/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 8/21/2010 48 Female 95 lb 5/18/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 4/19/2012 74 Female 117 lb 5/18/2012 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 12/10/2011 63 Male 132 lb 5/18/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 80 Female 5/25/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/13/2010 65 Female 5/25/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperuricaemia Hospitalization 2/22/2012 66 Male 5/25/2012 Other Health Professional Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 11/4/2011 45 Female 220 lb 5/30/2012 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 5/19/2011 83 Male 132 lb 5/30/2012 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 2/22/2012 66 Male 5/30/2012 Japan
Primary
Concomitant
Renal Tubular Necrosis Other Serious 3/15/2012 59 Male 6/6/2012 Japan
Primary
Concomitant
Renal Cell Carcinoma Death 5/19/2011 83 Male 132 lb 6/6/2012 Physician Japan
Primary
Concomitant
Lung Disorder Hospitalization 9/29/2010 69 Male 137 lb 6/12/2012 Physician Japan
Primary
Concomitant
Soft Tissue Infection Other Serious 10/5/2009 78 Male 6/13/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 3/15/2012 59 Male 141 lb 6/13/2012 Physician Japan
Primary
Secondary
Concomitant
Colitis Hospitalization 2/6/2012 62 Male 117 lb 6/21/2012 Pharmacist Japan
Primary
Secondary
Ileus Hospitalization 4/5/2012 62 Male 130 lb 6/21/2012 Physician Japan
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 5/22/2012 78 Male 122 lb 7/5/2012 Physician Japan
Primary
Concomitant
Colitis Hospitalization 2/6/2012 62 Male 117 lb 7/5/2012 Physician Japan
Primary
Secondary
Erythema Hospitalization 4/27/2012 56 Male 7/10/2012 Japan
Primary
Concomitant
Cardiac Arrest Death 3/24/2012 64 Male 7/10/2012 Physician Japan
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Life Threatening 8/3/2011 44 Female 7/11/2012 Physician Japan
Primary
Concomitant
Depression Other Serious 2/22/2012 66 Male 7/17/2012 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 12/28/2011 40 Male 7/17/2012 Japan
Primary
Concomitant
Neoplasm Malignant Death 11/15/2011 45 Female 220 lb 7/18/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 5/1/2012 72 Male 7/19/2012 Other Health Professional Japan
Primary
Concomitant

Drug Data