Acetaminophen combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/6/2006 50 Male 110 lb 1/19/2006 Pharmacist United States
Primary
Concomitant
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/10/2005 56 Female 2/17/2006 France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/10/2005 56 Female 2/16/2006 France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism 1/12/2006 70 Female 1/23/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/27/2004 56 Female 106 lb 2/21/2006 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pregnancy On Oral Contraceptive Other Serious 9/30/2004 Female 126 lb 3/22/2006 Physician Brazil
Primary
Secondary
Concomitant
Throat Tightness Other Serious 3/7/2006 36 Male 132 lb 3/9/2006 United States
Primary
Concomitant
Sepsis Hospitalization 2/17/2006 Female 210 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 3/20/2006 55 Male 3/31/2006 India
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 3/20/2006 55 Male 4/6/2006 Other Health Professional India
Primary
Concomitant
Delirium Other Serious 3/15/2006 39 Male 4/25/2006 Other Health Professional Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/10/2005 56 Female 4/20/2006 France
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Hypotension Other Serious 9/30/2004 Female 126 lb 5/9/2006 Physician Brazil
Primary
Secondary
Concomitant
Delirium Other Serious 3/15/2006 39 Male 6/1/2006 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Life Threatening 5/3/2006 70 Male 6/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 6/9/2006 Other Health Professional Hungary
Primary
Concomitant
Delirium Other Serious 3/15/2006 39 Male 6/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/31/2005 Female 152 lb 6/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 7/14/2006 87 Male 161 lb 8/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/1/2005 56 Female 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
Uveitis Hospitalization 7/1/2003 31 Female 8/14/2006 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/31/2006 62 Female 140 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Urine Output Decreased Other Serious 4/1/2005 56 Female 8/17/2006 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 8/7/2006 59 Female 157 lb 8/31/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/30/2006 59 Female 157 lb 8/29/2006 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Pressure Hospitalization 8/21/2006 59 Female 152 lb 9/1/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 12/1/2004 62 Male 160 lb 9/8/2006 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 12/21/2004 62 Male 9/14/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/24/2004 36 Female 99 lb 10/9/2006 Physician Japan
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 10/26/2005 65 Female 10/5/2006 France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2005 67 Female 10/11/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 10/11/2006 83 Male 158 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 10/19/2006 Physician Germany
Primary
Secondary
Concomitant
Somnolence Death 7/11/2006 Male 146 lb 10/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Pyrexia Other Serious 5/18/2006 78 Female 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 11/20/2006 Other Health Professional Hungary
Primary
Concomitant
Sedation Life Threatening 5/29/2006 82 Male 12/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 12/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Vomiting Required Intervention 7/9/2006 40 Male 191 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/4/2005 Male 134 lb 1/12/2007 Belgium
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 4/7/2006 67 Male 1/15/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Tuberculosis Hospitalization 7/23/2006 67 Male 1/29/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Vomiting Other Serious 6/4/2005 Male 134 lb 2/15/2007 Belgium
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 4/7/2006 67 Male 2/13/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Postoperative Wound Complication Required Intervention 4/1/2006 54 Male 288 lb 8/7/2006 Pharmacist United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Tendon Disorder Disability 2/10/2007 49 Female 6/26/2007 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 33 Male 7/17/2007 Germany
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 33 Male 7/20/2007 Germany
Primary
Secondary
Toxic Shock Syndrome Death 10/28/2004 84 Male 8/2/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 6/5/2007 58 Male 145 lb 8/22/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 12/28/2006 Female 105 lb 1/4/2007 Pharmacist United States
Primary
Concomitant
Metabolic Acidosis Death 53 Male 8/21/2007 United Kingdom
Primary
Secondary
Urine Abnormality Other Serious 1 Male 8/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/24/2006 Female 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 9/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 53 Male 9/27/2007
Primary
Secondary
Concomitant
Urine Amino Acid Level Increased Other Serious 53 Male 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 9/27/2007 Male 12/6/2007 Pharmacist United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 12/13/2007 United States
Primary
Secondary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/3/2007 85 Female 126 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 12/29/2007 72 Male 1/4/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 53 Male 1/22/2008 United Kingdom
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms 12/14/2007 53 Male 12/19/2007 United States
Primary
Concomitant
Suicide Attempt Hospitalization 2/14/2008 Female 183 lb 2/22/2008 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 3/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/12/2008 Female 183 lb 3/14/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Life Threatening 12/26/2007 Female 3/26/2008 Other Health Professional Italy
Primary
Secondary
Convulsion Other Serious 3/29/2008 Pharmacist Japan
Primary
Secondary
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 53 Male 4/17/2008 United Kingdom
Primary
Secondary
Concomitant
Urine Ketone Body Present Hospitalization 82 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Aspiration Hospitalization 88 Female 4/29/2008 United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 3/23/2008 Female 101 lb 5/5/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2007 Female 155 lb 5/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 33 Male 5/8/2008 Other Health Professional Italy
Primary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 12/24/2007 75 Male 6/9/2008 Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/13/2008 70 Male 6/16/2008 Physician Philippines
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/25/2008 50 Male 5/30/2008 France
Primary
Secondary
Concomitant
Nausea Other Serious 82 Female 6/25/2008 Other Health Professional Japan
Primary
Secondary
Ventricular Tachycardia Life Threatening 10/5/2007 49 Male 6/23/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vascular Graft Other Serious 3/24/2008 Male 134 lb 7/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 7/22/2008 United Kingdom
Primary
Secondary
Sputum Discoloured Life Threatening 12/24/2007 75 Male 7/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Angioedema Other Serious 10/5/2007 73 Female 170 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Ventricular Septal Defect Other Serious Female 8/12/2008 United Kingdom
Primary
Concomitant
Deafness Neurosensory Other Serious 2/3/2008 46 Male 173 lb 8/21/2008 Pharmacist United States
Primary
Concomitant
Urine Abnormality Hospitalization 8/13/2008 78 Male 9/5/2008 Other Health Professional United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 8/11/2008 74 Female 145 lb 9/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 9/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 10/1/2008 Physician United States
Primary
Concomitant
Urine Ketone Body Present Hospitalization 82 Female 9/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/6/2008 Female 160 lb 10/10/2008 Pharmacist United States
Primary
Concomitant
Hepatic Failure Other Serious 12/21/2007 Female 133 lb 10/15/2008 Physician Canada
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/4/2008 61 Male 121 lb 10/13/2008 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/21/2008 66 Male 10/14/2008 Physician Japan
Primary
Concomitant
Cough Hospitalization 88 Female 10/20/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/6/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/11/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Rash Erythematous Life Threatening 3/12/2008 Male 195 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Interacting
Pneumonia Hospitalization 4/14/2008 Female 250 lb 11/24/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/10/2008 63 Male 202 lb 11/19/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/20/2008 United States
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 8/10/2008 63 Male 202 lb 11/19/2008 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/4/2008 61 Male 121 lb 11/24/2008 Physician Japan
Primary
Concomitant
Myocardial Infarction Other Serious 53 Male 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Tubulointerstitial Nephritis Hospitalization 10/14/2007 31 Female 12/16/2008 Japan
Primary
Secondary
Pneumonia Hospitalization 4/14/2008 Female 250 lb 12/18/2008 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization 3/5/2008 Female 12/23/2008 Other Health Professional France
Primary
Concomitant
Interacting
Platelet Count Decreased Death 3/18/2008 Male 190 lb 12/24/2008 Other Health Professional Turkey
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 10/14/2007 31 Female 1/6/2009 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/9/2007 1/16/2009 Physician Singapore
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 11/9/2007 1/26/2009 Physician Singapore
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 11/20/2008 24 Male 140 lb 1/26/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Injection Site Pruritus Other Serious 7/17/2008 76 Female 155 lb 2/15/2009 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 1/15/2009 72 Male 2/27/2009 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 7/1/2008 Male 207 lb 3/9/2009 Pharmacist
Primary
Concomitant
Rash Other Serious 1/15/2009 Male 3/17/2009 Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/28/2006 68 Male 181 lb 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data