Acetaminophen combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Syndrome Required Intervention 11/1/2005 23 Female 139 lb 12/5/2005 United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 5/16/2005 58 Male 249 lb 12/1/2005 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 1/13/2006 39 Female 227 lb 2/2/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Death 10/27/2005 76 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/17/2006 73 Male 141 lb 3/13/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/15/2006 64 Male 243 lb 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/26/2004 65 Female 370 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 5/14/2006 38 Male 5/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Death 10/27/2005 76 Male 6/5/2006 Physician United States
Primary
Secondary
Concomitant
Streptococcal Infection Life Threatening 5/14/2006 38 Male 6/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ulcer Death 10/27/2005 Male 6/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2006 56 Male 176 lb 6/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Streptococcal Life Threatening 5/14/2006 38 Male 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/20/2006 60 Female 7/6/2006 Physician Thailand
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/9/2006 56 Male 176 lb 7/11/2006 Consumer United States
Primary
Secondary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 10/24/2005 Male 8/11/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/28/2003 35 Female 8/4/2006 United States
Primary
Concomitant
Tachycardia Hospitalization 10/24/2005 52 Male 149 lb 8/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/24/2005 52 Male 149 lb 8/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/9/2006 56 Male 176 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 56 Male 176 lb 8/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Death 7/11/2006 Male 146 lb 10/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/19/2006 Female 11/17/2006 Physician Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/29/2006 Male 11/20/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 64 Male 159 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 1/26/2006 69 Male 12/1/2006 Consumer United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 8/19/2005 Male 12/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 12/29/2006 Male 192 lb 1/5/2007 Other Health Professional
Primary
Secondary
Concomitant
Angioedema Life Threatening 5/5/2006 68 Female 2/23/2007 Physician Australia
Primary
Secondary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Illusion Other Serious 3/6/2007 78 Female 128 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 3/6/2007 Female 128 lb 7/5/2007 Consumer United States
Primary
Secondary
Concomitant
Trichiasis Other Serious 5/30/2007 Female 7/17/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Hospitalization 3/28/2007 Male 119 lb 7/17/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/7/2007 Female 128 lb 7/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 5/1/2005 Female 128 lb 7/24/2007 Consumer Switzerland
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/1/2007 64 Female 107 lb 1/30/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Disability 5/16/2007 Female 1/30/2008 Physician Hungary
Primary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 2/11/2008 Physician Australia
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/16/2007 Female 2/13/2008 Physician Hungary
Primary
Concomitant
Melaena Hospitalization 1/13/2008 Male 2/27/2008 Physician France
Primary
Secondary
Concomitant
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Melaena Hospitalization 1/13/2008 Male 3/12/2008 Physician France
Primary
Secondary
Concomitant
Viral Infection Other Serious 4/1/2007 Female 107 lb 3/24/2008 Physician United States
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 3/20/2008 Female 130 lb 3/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/12/2007 Male 3/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 4/9/2008 Other Health Professional
Primary
Secondary
Concomitant
Carotid Artery Occlusion Hospitalization 3/27/2008 60 Male 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 3/27/2008 60 Male 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/6/2007 Female 5/12/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Male 5/13/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Death 3/8/2008 Male 5/14/2008 Physician France
Primary
Concomitant
Transaminases Increased Hospitalization 4/30/2008 Male 143 lb 5/15/2008 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/1/2008 Male 90 lb 5/22/2008 South Africa
Primary
Secondary
Concomitant
Appendicitis Perforated Hospitalization 7/16/2008 Female 7/28/2008 Canada
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/21/2008 Female 120 lb 7/28/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/4/2008 Male 143 lb 8/8/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vasculitis Cerebral Hospitalization 6/11/2008 Female 8/25/2008 Physician France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/21/2008 Female 120 lb 9/5/2008 Physician United States
Primary
Secondary
Concomitant
Dysphagia 7/23/2008 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/21/2008 Female 120 lb 9/10/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 9/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 6/27/2008 52 Male 7/18/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Chest Pain Hospitalization 5/1/2005 Female 128 lb 11/7/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/3/2008 Male 11/10/2008 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 11/12/2008 Physician United States
Primary
Secondary
Concomitant
Perinephric Collection Hospitalization 9/25/2007 Male 11/19/2008 Physician Australia
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 10/4/2008 Male 12/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 8/7/2008 Female 133 lb 12/24/2008 Other Health Professional Canada
Primary
Concomitant
Osteoarthritis Hospitalization 8/7/2008 Female 133 lb 12/24/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/17/2008 Female 120 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 64 Male 1/12/2009
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 59 Female 4/2/2009 Physician United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Hospitalization 48 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Required Intervention 4/27/2009 66 Female 7/1/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Required Intervention 4/27/2009 66 Female 7/9/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2009 Male 104 lb 7/24/2009 United States
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 2/13/2008 Male 133 lb 8/20/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 2/13/2008 Male 133 lb 9/7/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Petechiae Hospitalization 8/25/2009 Male 228 lb 9/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 77 Female 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 7/23/2009 Female 174 lb 10/7/2009 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/23/2009 Female 10/9/2009 Consumer Australia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/8/2009 56 Male 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 8/1/2009 59 Male 10/26/2009 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Distress Death 10/21/2009 69 Male 197 lb 1/6/2010 Pharmacist United States
Primary
Concomitant
Proteinuria Hospitalization 1/4/2010 68 Female 184 lb 1/14/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 1/4/2010 68 Female 184 lb 2/2/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 132 lb 2/4/2010 Physician United States
Primary
Concomitant
Syncope Hospitalization 2/3/2010 69 Male 238 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 2/3/2010 Male 238 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/8/2009 56 Male 3/1/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Folliculitis Hospitalization 8/25/2009 61 Male 228 lb 3/25/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 8/21/2009 60 Male 4/14/2010 Physician France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 13 Male 88 lb 5/3/2010 Other Health Professional Canada
Primary
Concomitant
Visual Impairment Life Threatening 4/25/2010 52 Male 354 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 6/3/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious Female 132 lb 7/9/2010 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2008 82 Male 150 lb 7/21/2010 Physician Spain
Primary
Secondary
Concomitant
Throat Tightness Other Serious 5/26/2010 56 Female 128 lb 8/18/2010 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/1/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/17/2010 64 Male 165 lb 9/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 10/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/7/2009 75 Female 97 lb 12/27/2010 Consumer Spain
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 167 lb 1/27/2011 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious Female 132 lb 1/31/2011 Physician United States
Primary
Concomitant
Perirectal Abscess 2/15/2011 34 Male 167 lb 2/15/2011 United States
Primary
Secondary
Concomitant
Diabetic Foot Infection Hospitalization 6/23/2009 78 Male 167 lb 3/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Foot Infection Hospitalization 6/23/2009 78 Male 167 lb 3/9/2011 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 15 Male 179 lb 3/9/2011 Other Health Professional Canada
Primary
Concomitant
Skin Ulcer Hospitalization 6/23/2009 78 Male 167 lb 3/22/2011 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/21/2011 16 Female 4/11/2011 Physician Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/21/2011 16 Female 4/18/2011 Physician Spain
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Cerebral Ischaemia Disability 8/29/2010 56 Female 108 lb 5/27/2011 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/29/2010 56 Female 6/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2011 23 Female 108 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/14/2011 78 Female 112 lb 6/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2011 23 Female 108 lb 6/14/2011 Physician United States
Primary
Secondary
Concomitant
Lung Transplant Other Serious 5/9/2011 62 Female 6/16/2011 Physician Ireland
Primary
Concomitant
Anastomotic Fistula Hospitalization 3/10/2010 56 Male 132 lb 6/29/2011 Physician France
Primary
Secondary
Concomitant
Paronychia Other Serious 9/13/2010 67 Female 95 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/1/2010 40 Male 126 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 1/30/2010 65 Female 7/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Anastomotic Fistula Hospitalization 3/10/2010 56 Male 132 lb 7/8/2011 Physician France
Primary
Secondary
Concomitant
Folliculitis Hospitalization 8/26/2009 61 Male 228 lb 7/18/2011 Physician France
Primary
Secondary
Concomitant
Folliculitis Hospitalization 8/26/2009 61 Male 228 lb 7/18/2011 Consumer France
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Other Serious 8/26/2009 61 Male 228 lb 7/19/2011 Physician France
Primary
Secondary
Concomitant
Anastomotic Ulcer Hospitalization 3/10/2010 59 Male 132 lb 8/4/2011 Physician France
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/6/2011 84 Male 163 lb 8/5/2011 Other Health Professional France
Primary
Secondary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Malaise Hospitalization 3/6/2011 84 Male 163 lb 8/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Hydrocephalus Hospitalization 3/6/2011 84 Male 163 lb 8/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cerebral Fungal Infection Life Threatening 7/10/2010 57 Male 163 lb 8/12/2011 Consumer Netherlands
Primary
Secondary
Concomitant

Drug Data