Acetaminophen combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 2/1/2003 59 Male 1/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/4/2006 31 Female 128 lb 1/25/2006 Physician Mexico
Primary
Concomitant
Osteitis Hospitalization 8/23/2004 Female 163 lb 2/15/2006 Netherlands
Primary
Concomitant
Vasculitis Death 32 Female 176 lb 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Eosinophilia Other Serious 7/1/2001 55 Female 3/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/5/2004 Female 3/27/2006 Pharmacist United Kingdom
Primary
Concomitant
Wheezing Hospitalization 3/6/2006 70 Female 3/15/2006 Colombia
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Female 126 lb 5/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Eosinophilia Other Serious 7/1/2001 55 Female 5/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 5/31/2006 Other Health Professional Australia
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 6/5/2006 Physician Australia
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 7/28/2006 Physician Belgium
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 8/10/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/7/2005 Female 126 lb 8/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wound Dehiscence Other Serious 7/29/2005 Female 117 lb 10/3/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/4/2005 Female 10/4/2006 Physician Belgium
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 10/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2006 Female 163 lb 10/18/2006 Netherlands
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 11/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Death Female 207 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 11/16/2006 Netherlands
Primary
Concomitant
Osteomyelitis Hospitalization 1/1/2006 Female 163 lb 11/20/2006 Netherlands
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 6/27/2006 Female 130 lb 11/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 4/15/2006 Female 143 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 8/29/2006 Female 121 lb 12/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 11/5/2006 66 Male 12/28/2006
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Hospitalization 10/4/2004 Male 223 lb 12/28/2006 Consumer United Kingdom
Primary
Concomitant
Hospitalisation Hospitalization Male 160 lb 1/4/2007 Pharmacist Canada
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Osteonecrosis Hospitalization 9/15/2003 67 Female 3/5/2007 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 12/18/2006 Male 160 lb 3/29/2007 Pharmacist Canada
Primary
Concomitant
Erythema Multiforme Other Serious 11/5/2000 70 Female 3/30/2007 Physician Spain
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 6/26/2007 Physician United States
Primary
Concomitant
Malaise Other Serious 9/1/2004 Female 238 lb 7/5/2007 Consumer United Kingdom
Primary
Concomitant
Throat Irritation Hospitalization 12/1/2005 Male 7/24/2007 Belgium
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 3/1/2007 68 Female 146 lb 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Limb Deformity Other Serious 1/1/2006 64 Female 139 lb 9/20/2007 Brazil
Primary
Concomitant
Pyrexia 11/21/2007 Female 12/15/2007 United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/21/2007 Female 139 lb 12/27/2007 United Kingdom
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 1/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious Female 140 lb 2/22/2008 Canada
Primary
Concomitant
Hypothermia Other Serious 10/16/2007 Male 121 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Life Threatening 11/7/2007 Male 251 lb 2/29/2008 United Kingdom
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 6/18/2007 Female 146 lb 3/6/2008 United Kingdom
Primary
Concomitant
Tibia Fracture Other Serious 9/22/2007 Female 150 lb 3/6/2008 Canada
Primary
Concomitant
Cerebral Infarction Life Threatening 12/15/2007 Female 3/28/2008 Spain
Primary
Concomitant
Peripheral Embolism Life Threatening 11/7/2007 Male 251 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 69 Male 4/18/2008 United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 10/24/2007 Female 154 lb 5/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Benign Respiratory Tract Neoplasm Hospitalization 5/2/2008 48 Male 5/16/2008 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/2/2008 48 Male 5/23/2008 Other Health Professional Sweden
Primary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 12/19/2007 Female 137 lb 6/6/2008 United Kingdom
Primary
Concomitant
Cerebral Infarction Life Threatening 12/15/2007 Female 7/10/2008 Spain
Primary
Concomitant
Cerebral Infarction Life Threatening 12/15/2007 Female 7/11/2008 Spain
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/2/2008 Male 7/22/2008 Sweden
Primary
Concomitant
Cerebral Infarction Life Threatening 11/7/2007 Female 7/30/2008 Spain
Primary
Concomitant
Rhinitis Allergic Other Serious 12/1/2007 Male 8/7/2008 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 7/30/2008 Female 150 lb 8/15/2008 Canada
Primary
Concomitant
Autoimmune Neutropenia Hospitalization 1/1/2001 56 Female 8/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 4/29/2008 Female 154 lb 8/21/2008 United Kingdom
Primary
Concomitant
Cerebral Infarction Life Threatening 11/7/2007 Female 9/4/2008 Spain
Primary
Concomitant
Gastritis Hospitalization 6/21/2008 Female 159 lb 9/4/2008 Germany
Primary
Secondary
Concomitant
Hunger 6/6/2008 Female 138 lb 9/12/2008 United States
Primary
Concomitant
Urticaria 7/1/2008 Female 200 lb 9/13/2008 United States
Primary
Concomitant
Death Other Serious Male 152 lb 10/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 12/19/2007 Female 137 lb 10/17/2008 United Kingdom
Primary
Concomitant
Muscular Weakness 6/1/2008 Female 140 lb 12/12/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 12/12/2008 United States
Primary
Concomitant
Psoriasis 10/16/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Atrial Flutter Other Serious 8/13/2008 59 Male 220 lb 12/31/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/29/2008 Male 194 lb 1/12/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 3/12/2008 Female 174 lb 1/20/2009 United Kingdom
Primary
Concomitant
Crohn's Disease Other Serious 1/1/2009 52 Female 5/15/2009 Consumer United Kingdom
Primary
Concomitant
Wheezing 9/1/2008 Female 214 lb 6/11/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 6/25/2009 73 Female 106 lb 7/24/2009
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/9/2008 Female 209 lb 8/19/2009 United Kingdom
Primary
Concomitant
Wound Other Serious 1/1/2009 Female 141 lb 8/19/2009 Brazil
Primary
Concomitant
Wrong Technique In Drug Usage Process 10/18/2006 Female 9/11/2009 Consumer United States
Primary
Concomitant
Peripheral Vascular Disorder Death Female 9/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Venous Thrombosis Other Serious 4/1/2007 Female 11/3/2009 Physician France
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 55 Female 114 lb 11/24/2009 Physician Canada
Primary
Concomitant
Opportunistic Infection Other Serious 11/2/2009 55 Female 114 lb 1/22/2010 Physician Canada
Primary
Concomitant
Opportunistic Infection Other Serious 11/2/2009 55 Female 114 lb 2/4/2010 Physician Canada
Primary
Concomitant
Pain Disability 8/8/2007 58 Female 7/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 6/25/2010 62 Female 7/23/2010 Other Health Professional Colombia
Primary
Concomitant
General Physical Health Deterioration Hospitalization 8/10/2010 Female 8/27/2010 Physician Belgium
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 8/23/2010 49 Female 209 lb 9/7/2010 Consumer Canada
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 72 Female 128 lb 9/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mitral Valve Disease Death 8/14/2009 66 Male 170 lb 11/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 11/17/2010 54 Female 12/22/2010 Pharmacist Colombia
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 7/20/2010 12/23/2010 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 12/1/2010 12/26/2010 Consumer Colombia
Primary
Concomitant
Hypertension Hospitalization 11/17/2010 54 Female 12/27/2010 Pharmacist Colombia
Primary
Concomitant
Hypersensitivity Hospitalization 11/17/2010 52 Female 1/5/2011 Pharmacist Colombia
Primary
Concomitant
Hypertension Hospitalization 11/17/2010 52 Female 1/12/2011 Pharmacist Colombia
Primary
Concomitant
Abscess Jaw Death 9/28/2010 64 Female 1/26/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Eye Haemorrhage Hospitalization 1/14/2011 37 Female 2/10/2011 Other Health Professional Colombia
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/28/2010 64 Female 2/15/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious Female 3/25/2011 Physician United States
Primary
Concomitant
Hypertension Life Threatening 4/10/2011 73 Female 5/13/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 4/10/2011 73 Female 5/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diabetic Foot Other Serious 12/1/2010 79 Male 5/7/2011 United Kingdom
Primary
Concomitant
Nasopharyngitis Other Serious 3/1/2010 71 Female 5/19/2011 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 4/10/2011 73 Female 5/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Encephalitis Hospitalization 64 Female 6/3/2011 Physician United Kingdom
Primary
Concomitant
Hypertension Life Threatening 4/10/2011 73 Female 5/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/3/2011 82 Female 6/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Death 73 Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 2/24/2011 82 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bursitis Other Serious 1/31/2011 72 Female 93 lb 6/23/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Pain Other Serious 5/1/2011 47 Female 6/28/2011 Physician France
Primary
Concomitant
Oropharyngeal Pain Other Serious 3/1/2010 71 Female 6/30/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/10/2011 73 Female 7/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 4/10/2011 73 Female 7/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Coronary Syndrome Death 5/17/2011 79 Female 99 lb 7/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Life Threatening 4/26/2011 74 Female 8/1/2011 Consumer United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 7/12/2011 62 Male 231 lb 8/2/2011 Pharmacist Germany
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 5/1/2011 64 Female 8/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Disability 7/25/2011 50 Female 198 lb 8/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Arthralgia Life Threatening 49 Female 185 lb 8/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Life Threatening 3/20/2011 49 Female 185 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 3/18/2009 61 Male 220 lb 8/17/2011 Physician United Kingdom
Primary
Concomitant
Arthralgia Life Threatening 49 Female 8/12/2011 United Kingdom
Primary
Concomitant
Joint Instability Other Serious 7/25/2011 50 Female 198 lb 8/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Alcohol Poisoning Hospitalization 8/1/2010 Female 8/30/2011 Physician Belgium
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 9/1/2010 71 Female 133 lb 9/7/2011 Physician United States
Primary
Concomitant
Alcohol Poisoning Hospitalization 8/1/2010 Female 9/16/2011 Physician Belgium
Primary
Secondary
Concomitant
Fatigue Other Serious 7/1/2011 47 Female 141 lb 9/16/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 69 9/20/2011 United Kingdom
Primary
Concomitant
Fatigue Disability 6/1/2011 45 Female 139 lb 9/30/2011 Consumer Netherlands
Primary
Concomitant
Fatigue Disability 6/1/2011 45 Female 139 lb 10/3/2011 Consumer Netherlands
Primary
Concomitant
Bone Lesion Other Serious 5/19/2011 63 Female 117 lb 10/4/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Arthralgia Hospitalization 1/14/2011 37 Female 10/4/2011 Consumer Colombia
Primary
Concomitant
Muscle Mass Other Serious Female 115 lb 10/6/2011 Consumer Brazil
Primary
Concomitant
Glomerular Filtration Rate Decreased 5/1/2011 64 Female 10/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Soft Tissue Mass Other Serious 1/31/2011 72 Female 93 lb 10/27/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Arthralgia Life Threatening 1/1/2011 49 Female 185 lb 10/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Iii Life Threatening 1/1/2011 49 Female 185 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Gastroenteritis Hospitalization 8/13/2010 69 Female 150 lb 11/25/2011 France
Primary
Secondary
Concomitant
Periodontal Disease Hospitalization 8/13/2010 69 Female 150 lb 12/1/2011 France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/19/2011 73 Female 12/1/2011 Physician Netherlands
Primary
Concomitant
Arthralgia Other Serious 11/1/2010 53 Female 161 lb 12/14/2011 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 10/12/2011 59 Female 12/15/2011 New Zealand
Primary
Concomitant
Drug Ineffective Hospitalization Male 143 lb 12/30/2011 Finland
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 74 Female 1/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 10/12/2011 59 Female 12/30/2011 New Zealand
Primary
Concomitant
Arthropathy Other Serious 5/19/2011 63 Female 117 lb 1/11/2012 Other Health Professional Taiwan, Province Of China
Primary
Concomitant

Drug Data