Acetaminophen combined with Lamotrigine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Life Threatening 1/6/2006 50 Male 110 lb 1/19/2006 Pharmacist United States
Primary
Concomitant
Rash 1/30/2006 Male 158 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 1/13/2006 Female 176 lb 2/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 54 Male 7/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/31/2005 Female 152 lb 6/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 9/15/2005 22 Male 2/8/2006 United States
Primary
Concomitant
Intentional Overdose Death 38 Female 9/13/2006 Physician United States
Primary
Secondary
Ventricular Tachycardia Death 2/15/2006 Male 235 lb United States
Primary
Concomitant
Hepatitis Other Serious 9/1/2006 32 Female 176 lb 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Hepatitis Death 9/1/2006 32 Female 176 lb 10/17/2006 United Kingdom
Primary
Secondary
Fatigue Other Serious 9/14/2006 40 Female 10/19/2006 Physician Sweden
Primary
Concomitant
Fatigue Other Serious 9/14/2006 40 Female 10/27/2006 Other Health Professional Sweden
Primary
Concomitant
Vomiting Other Serious 42 Male 1/3/2007 Consumer Ireland
Primary
Secondary
Vomiting Other Serious 42 Male 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 18 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Weight Decreased Hospitalization 1/1/2000 Male 3/15/2007 Other Health Professional France
Primary
Concomitant
Completed Suicide Death Female 3/30/2007 Pharmacist United States
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 6/1/2007 13 Female 229 lb 7/17/2007 Physician Canada
Primary
Concomitant
Vomiting Required Intervention 17 Female 132 lb 10/31/2007 Physician Norway
Primary
Concomitant
Obstructive Airways Disorder Life Threatening 9/14/2007 75 Male 146 lb 11/16/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2007 Male 12/27/2007 Physician Germany
Primary
Secondary
Vomiting Other Serious 12/17/2007 19 Male 12/26/2007 Other Health Professional Germany
Primary
Secondary
Hepatotoxicity Hospitalization 2 Female 1/8/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 31 Female 1/14/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 39 Male 1/15/2008 Physician United States
Primary
Secondary
Ventricular Tachycardia Hospitalization 31 Female 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 26 Male 1/15/2008 Physician United States
Primary
Secondary
Ventricular Tachycardia Death 31 Female 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Thinking Abnormal Hospitalization 4/24/2005 51 Male 206 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 26 Male 1/21/2008 United States
Primary
Secondary
Completed Suicide Death 39 Male 1/21/2008 United States
Primary
Secondary
Poisoning Death 39 Male 1/22/2008 Physician United States
Primary
Secondary
Completed Suicide Other Serious 26 Male 2/19/2008 Physician United States
Primary
Concomitant
Liver Injury Other Serious 3/25/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/19/2008 United Kingdom
Primary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Disability 46 4/15/2008 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 46 5/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/2/2008 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 5/5/2008 29 Female 123 lb 6/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
No Adverse Event 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Pain 1/1/2008 Female 118 lb 6/12/2008 Consumer United States
Primary
Concomitant
Malaise Other Serious Male 6/25/2008 Physician United Kingdom
Primary
Concomitant
Oligohydramnios Other Serious 7/23/2007 Female 7/9/2008 Consumer France
Primary
Concomitant
Pickwickian Syndrome Death 4/15/2008 Male 7/21/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 4/26/2008 29 Female 123 lb 9/24/2008
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/5/2008 29 Female 123 lb 10/3/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3 Female 9/29/2008 United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution 9/12/2008 Female 156 lb 10/21/2008 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 26 Male 10/30/2008 Physician United States
Primary
Secondary
Completed Suicide 26 Male 10/31/2008 Physician United States
Primary
Secondary
Ventricular Tachycardia Other Serious 31 Female 11/5/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Other Serious 6/17/2008 Female 143 lb 12/22/2008 Consumer United Kingdom
Primary
Concomitant
Visual Acuity Reduced Hospitalization 46 12/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 51 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 51 Male 1/5/2009 Physician United States
Primary
Secondary
Completed Suicide Death 51 Male 1/13/2009 Physician United States
Primary
Secondary
Victim Of Child Abuse Hospitalization 0 Male 3/16/2009 United Kingdom
Primary
Secondary
Victim Of Child Abuse Hospitalization 0 Male 3/20/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 10/21/2002 45 Female 136 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 3/3/2009 42 Female 6/2/2009 United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 51 Female 300 lb 6/18/2009 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 50 Female 7/15/2009 United States
Primary
Concomitant
Pneumonia Other Serious 19 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Pneumonia Other Serious 2 Female 7/16/2009 Netherlands
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/29/2009 Male 189 lb 8/18/2009 United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 7/6/2005 51 Male 181 lb 8/20/2009 United States
Primary
Concomitant
Epilepsy Hospitalization 3/12/2008 47 Female 148 lb 8/21/2009 Physician France
Primary
Concomitant
Completed Suicide Death 8/28/2009 Physician United States
Primary
Secondary
Completed Suicide Death 8/28/2009 Physician United States
Primary
Secondary
Completed Suicide Death 31 Female 9/7/2009 Physician United States
Primary
Secondary
Concomitant
Social Avoidant Behaviour Hospitalization 1/1/2007 0 Male 9/15/2009 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 2/11/2002 52 Female 211 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Urine Alcohol Test Positive Required Intervention 5/21/2009 47 Male 193 lb 5/27/2009 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 7/30/2009 Female 11/9/2009 Consumer Sweden
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/30/2009 Female 11/10/2009 Consumer Sweden
Primary
Secondary
Concomitant
Drug Toxicity Death 48 Female 142 lb 12/15/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 37 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 37 Female 2/2/2010 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 37 Female 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 21 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 37 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Death Death 67 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Headache 10/24/2007 45 Female 161 lb 7/17/2010 Consumer United States
Primary
Concomitant
Dry Mouth Other Serious Male 8/2/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/19/2010 57 Male 172 lb 9/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Stress Hospitalization 9/14/2010 38 Female 215 lb 9/27/2010 Consumer United States
Primary
Concomitant
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 12/9/2010 Female 218 lb 12/17/2010 Consumer Brazil
Primary
Concomitant
Parkinsonism Hospitalization 5/1/2010 69 Female 12/2/2010 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 12/1/2010 22 Female 115 lb 12/22/2010 Physician United States
Primary
Concomitant
Pregnancy Female 11/10/2010 Physician United States
Primary
Concomitant
Epilepsy Other Serious 40 Male 12/7/2010 Consumer United Kingdom
Primary
Concomitant
Tachycardia Other Serious 4/26/2006 57 Female 1/3/2011 Consumer United Kingdom
Primary
Concomitant
Completed Suicide Death 60 Female 1/5/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2009 65 Male 1/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 38 Male 1/9/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/12/2011 Physician United States
Primary
Secondary
Concomitant
Alopecia Hospitalization 25 Female 1/12/2011 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Death 65 Male 1/12/2011 Physician United States
Primary
Secondary
Haematoma Hospitalization 9/26/2010 70 Female 1/12/2011 Consumer Canada
Primary
Concomitant
Completed Suicide Death 65 Male 1/13/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 60 Female 1/14/2011 Physician United States
Primary
Secondary
Haematoma Hospitalization 9/26/2010 70 Female 159 lb 1/14/2011 Physician Canada
Primary
Concomitant
Dementia Hospitalization 9/26/2010 70 Female 159 lb 1/18/2011 Physician Canada
Primary
Concomitant
Death Death 38 Male 1/19/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2010 65 Male 1/6/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2009 60 Female 1/26/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Other Serious 65 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 60 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 65 Male 1/27/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 65 Male 1/20/2011 United States
Primary
Secondary
Poisoning Death 1/1/2009 38 Male 1/27/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2009 65 Male 1/27/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2009 65 Male 1/27/2011 United States
Primary
Secondary
Completed Suicide Death 1/1/2009 60 Female 1/26/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 2/2/2011 United States
Primary
Secondary
Completed Suicide Death 65 Male 3/6/2011 Physician United States
Primary
Secondary
Completed Suicide Death 60 Female 3/7/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 3/7/2011 Physician United States
Primary
Secondary
Abnormal Behaviour Hospitalization 25 Female 3/16/2011 Consumer United States
Primary
Concomitant
Rash Other Serious 43 Male 3/21/2011 Consumer United States
Primary
Concomitant
Alcohol Poisoning Death 53 Female 4/15/2011 Other Health Professional United States
Primary
Secondary
Drug Interaction Other Serious 4/4/2011 Male 4/18/2011 Consumer Denmark
Primary
Secondary
Toxicity To Various Agents Death 53 Female 4/22/2011 Consumer United States
Primary
Secondary
Toxicity To Various Agents Death 53 Female 4/26/2011 Other Health Professional United States
Primary
Secondary
Malaise Other Serious 4/5/2011 43 Male 4/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 4/19/2011 42 Female 138 lb 5/3/2011 United States
Primary
Secondary
Concomitant

Drug Data