Acetaminophen combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Bladder Disorder Hospitalization 2/13/2006 Female 140 lb 2/24/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Other Serious 12/1/2004 77 5/11/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Required Intervention 6/27/2005 77 Male 155 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Vomiting 2/9/2006 81 Female 201 lb 4/17/2006 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/26/2006 85 Male 200 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Other Serious 8/29/2006 81 Male 117 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Toxic Epidermal Necrolysis Other Serious 10/11/2000 54 Female 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 8/9/2006 76 Female 99 lb 12/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/9/2006 76 Female 12/13/2006 France
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 66 Male 12/14/2006 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 8/9/2006 76 Female 12/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/9/2006 76 Female 12/19/2006 France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/6/2006 71 Male 1/16/2007 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 66 Male 2/15/2007 Other Health Professional Switzerland
Primary
Concomitant
Shock Life Threatening 2/8/2007 3/5/2007 Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/23/2006 69 Male 251 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Shock Life Threatening 2/8/2007 73 Female 101 lb 7/3/2007 Japan
Primary
Concomitant
Myocardial Infarction Life Threatening 7/18/2007 60 Male 179 lb 7/19/2007 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2007 Male 10/29/2007 Physician Germany
Primary
Concomitant
Coronary Artery Disease Death 9/24/2007 54 Female 12/13/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 8/25/2003 Female 2/29/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 8/25/2003 Female 3/11/2008 Physician Germany
Primary
Secondary
Vomiting Hospitalization 4/9/2007 85 Female 150 lb 3/7/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2006 Male 245 lb 5/16/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 5/1/2008 67 Male 5/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 5/29/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 6/2/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/13/2008 70 Male 6/16/2008 Physician Philippines
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 9/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 8/1/2008 59 Female 12/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/18/2008 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/18/2008 4/8/2009 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 5/5/2006 59 Male 257 lb 6/2/2009 United States
Primary
Concomitant
Vomiting Death 86 Female 7/20/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 9/7/2008 53 Male 243 lb 8/12/2009 United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Hypoxia Hospitalization 7/13/2009 66 Female 10/6/2009 Germany
Primary
Concomitant
Hypoxia Hospitalization 7/13/2009 66 Female 10/8/2009 Germany
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization Female 189 lb 4/1/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/6/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/18/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/26/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Torsade De Pointes Other Serious 79 Female 6/18/2010 Other Health Professional Australia
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/1998 41 Female 218 lb 8/6/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 9/30/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Petechiae Other Serious 9/6/2010 57 Male 143 lb 9/10/2010 Pharmacist United States
Primary
Concomitant
Wrist Fracture Other Serious 93 Female 9/9/2010 United States
Primary
Concomitant
Incorrect Drug Administration Duration Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 81 Female 11/3/2010 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 11/17/2007 75 Male 165 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/30/2004 49 Male 11/19/2010 United States
Primary
Concomitant
Visual Impairment Other Serious 10/13/2009 Female 11/24/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/13/2010 79 Female 11/24/2010 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/13/2010 79 Female 11/28/2010 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/13/2010 79 Female 11/30/2010 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 77 Male 159 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 36 Female 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/13/2010 79 Female 12/9/2010 Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2008 84 Female 12/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/1/2000 59 Female 119 lb 12/22/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Fungal Hospitalization 7/26/2010 51 Male 198 lb 1/3/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/25/2010 78 Male 3/22/2011 Physician Canada
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/12/2011 86 Female 150 lb 3/2/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Tooth Disorder 2/1/2011 85 Male 4/4/2011 Consumer United States
Primary
Concomitant
Erythema Disability 5/11/2006 69 Male 202 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 1/12/2011 71 Male 147 lb 4/14/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Sluggishness Hospitalization 1/15/2011 89 Female 4/19/2011 Consumer United States
Primary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Bronchitis Hospitalization 72 Female 215 lb 4/27/2011 Consumer United States
Primary
Concomitant
Electrocardiogram Pr Shortened Death 1/30/2011 81 Female 117 lb 5/11/2011 Consumer Switzerland
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 82 Female 115 lb 5/3/2011 United States
Primary
Concomitant
Renal Failure Other Serious 12/26/2007 73 Male 174 lb 5/21/2011 Other Health Professional United States
Primary
Concomitant
Nephrotic Syndrome Hospitalization 3/8/2011 31 Male 5/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anxiety Hospitalization 3/15/2002 44 Male 233 lb 5/28/2011 Consumer United States
Primary
Concomitant
Congo-crimean Haemorrhagic Fever Other Serious 10/18/2000 61 Male 6/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 6/2/2011 Pharmacist Japan
Primary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 6/9/2011 Pharmacist Japan
Primary
Concomitant
Neutropenia Death 73 Female 6/15/2011 Physician United Kingdom
Primary
Concomitant
Cellulitis Hospitalization 9/9/2009 74 Female 6/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 141 lb 6/27/2011 Pharmacist Japan
Primary
Concomitant
Liver Disorder Life Threatening 10/4/2010 7/1/2011 Physician Japan
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 141 lb 7/6/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 6/17/2011 67 Male 7/6/2011 Physician United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 12/1/2006 79 Male 187 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Atelectasis Hospitalization 10/18/2000 61 Male 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Connective Tissue Disorder Other Serious 10/18/2000 61 Male 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 6/1/2011 46 Male 195 lb 8/6/2011 Consumer United States
Primary
Concomitant
Abscess Jaw Other Serious 4/28/2006 73 Male 175 lb 8/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 6/16/2011 89 Female 8/12/2011 Other Health Professional France
Primary
Secondary
Concomitant
Fall Other Serious 6/16/2011 89 Female 8/12/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 10/18/2000 61 Male 8/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Dizziness Other Serious 6/16/2011 89 Female 8/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Inflammatory Bowel Disease Hospitalization 2/1/2011 62 Female 163 lb 8/24/2011 Physician United States
Primary
Concomitant
Erythema Death 5/1/2011 70 Female 339 lb 8/31/2011 Physician United States
Primary
Secondary
Concomitant
Haematochezia Hospitalization 11/22/2010 72 Female 124 lb 9/1/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Blood Glucose Increased Other Serious 7/1/2010 72 Female 111 lb 8/31/2011 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 6/16/2011 89 Female 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Death 5/1/2011 70 Female 339 lb 9/19/2011 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 11/22/2010 72 Female 124 lb 9/16/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Hernia Other Serious 7/1/2011 74 Male 174 lb 10/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Death 12/26/2007 73 Male 174 lb 10/20/2011 Other Health Professional United States
Primary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Pain Death 12/26/2007 73 Male 174 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Blister Other Serious 10/19/2011 65 Female 136 lb 11/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious Male 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious Male 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 4/28/2006 73 Male 175 lb 11/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Eructation 7/17/2011 82 Female 11/18/2011 Consumer United States
Primary
Concomitant
Hydrocephalus Other Serious Male 11/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Gout Other Serious 5/11/2006 69 Male 202 lb 11/24/2011 Other Health Professional United States
Primary
Concomitant
Gastric Cancer Other Serious 12/30/2010 63 Male 11/28/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Murmur Death 74 Male 179 lb 11/17/2011 Lawyer United States
Primary
Concomitant
Abscess Jaw Hospitalization 4/28/2006 73 Male 175 lb 12/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Androgen Deficiency Disability 45 Male 253 lb 11/23/2011 Lawyer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 2/9/2008 75 Female 180 lb 11/29/2011 Lawyer United States
Primary
Concomitant
Heart Rate Increased Life Threatening Female 120 lb 11/29/2011 Lawyer United States
Primary
Concomitant
Diarrhoea Other Serious Male 12/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Sarcoidosis Other Serious Male 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Balance Disorder Other Serious Male 12/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Fall Hospitalization 11/1/2011 91 Male 1/12/2012 Physician United Kingdom
Primary
Concomitant
Accidental Exposure 1/11/2012 84 Female 1/18/2012 Consumer United States
Primary
Concomitant
Hypothyroidism Other Serious Male 1/18/2012 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 10/1/2010 Male 1/18/2012 Consumer United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/21/2011 80 Male 195 lb 11/28/2011 Pharmacist United States
Primary
Secondary
Concomitant
Joint Range Of Motion Decreased Other Serious 10/1/2010 86 Male 1/27/2012 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious Female 197 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Deafness Bilateral Other Serious 1/1/2009 70 Female 2/1/2012 Consumer United States
Primary
Concomitant
Cerebral Ventricle Dilatation Other Serious Male 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Death 11/1/2011 91 Male 2/3/2012 Consumer United Kingdom
Primary
Concomitant
Renal Disorder Disability 8/19/2011 50 Female 112 lb 2/9/2012 Physician Japan
Primary
Concomitant
Blood Glucose Abnormal Hospitalization Male 180 lb 2/23/2012 Other Health Professional United States
Primary
Concomitant

Drug Data