Acetaminophen combined with Hydromorphone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain Death 75 Female 4/5/2006 Physician Canada
Primary
Concomitant
Thrombosis Death 42 Male 176 lb 11/24/2006 Pharmacist Canada
Primary
Concomitant
Drug Toxicity Death 78 Female 12/29/2008 Physician United States
Primary
Secondary
Thrombosis Other Serious 11/15/2008 Female 1/6/2009 Physician Canada
Primary
Concomitant
Weight Decreased Female 6/10/2009 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2007 59 Female 6/16/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/2/2009 79 Male 171 lb 9/3/2009 Other Health Professional United States
Primary
Concomitant
Pelvic Infection Required Intervention 6/23/2009 25 Female 178 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Pallor Life Threatening 8/10/2009 64 Male 195 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Diverticulitis Hospitalization 4/18/2008 59 Male 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2008 Male 126 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Required Intervention 4/1/2009 Male 161 lb 8/24/2009 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 10/10/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 52 Female 10/12/2009 United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 2/1/2009 Female 10/20/2009 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 10/7/2009 69 10/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 10/28/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 2/21/2008 Female 10/28/2009 Lawyer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/19/2009 Male 160 lb 10/30/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 53 Male 1/26/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death Female 2/27/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death Male 2/27/2010 Consumer United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 1/1/2008 59 Male 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 53 Male 4/6/2010 Physician United States
Primary
Secondary
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious 2/25/2010 53 Male 215 lb 5/11/2010 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 4/25/2010 54 Male 137 lb 6/2/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 43 Male 207 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 11/1/2008 13 Female 64 lb 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/30/2010 62 Female 129 lb 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 10/4/2004 57 Male 212 lb 7/30/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 1/19/2008 17 Male 220 lb 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 44 Female 172 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/28/2010 73 Male 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 10/4/2004 57 Male 212 lb 8/16/2010 Physician United States
Primary
Concomitant
Pancytopenia Life Threatening 8/2/2010 86 Female 133 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/28/2010 73 Male 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 3/1/2009 78 Female 121 lb 8/20/2010 Physician Switzerland
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/19/2007 58 Male 8/23/2010 Physician Canada
Primary
Secondary
Concomitant
Dyspepsia 10/30/2007 45 Female 139 lb 8/23/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/14/2007 43 Male 207 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Other Serious 3/1/2009 78 Female 121 lb 8/26/2010 Physician Switzerland
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/1/2010 75 Male 179 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haematoma Death 50 Female 10/11/2010 Other Health Professional Canada
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 3/1/2008 16 Female 130 lb 12/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 73 Male 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 70 Female 1/10/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/13/2011 Physician United States
Primary
Secondary
Troponin I Increased Other Serious 2/1/2006 52 Female 1/17/2011 United States
Primary
Concomitant
Completed Suicide Death 70 Female 1/19/2011 Physician United States
Primary
Secondary
Tachycardia Death 2/1/2008 27 Female 154 lb 1/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2009 70 Female 1/27/2011 Physician United States
Primary
Secondary
Poisoning Death 1/1/2009 70 Female 1/27/2011 Physician United States
Primary
Secondary
Drug Ineffective Hospitalization 17 Male 2/16/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 2/22/2011 Physician United States
Primary
Secondary
Spleen Congestion Death 9/2/2008 28 Male 185 lb 2/23/2011 Lawyer United States
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 10/4/2004 57 Male 212 lb 2/24/2011 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death Female 2/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 3/1/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 3/1/2011 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 2/4/2010 62 Male 141 lb 3/3/2011 Physician United States
Primary
Secondary
Concomitant
Chills Death 1/21/2011 62 Female 110 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 70 Female 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 1/21/2011 62 Female 110 lb 3/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alcohol Poisoning Death 53 Female 4/15/2011 Other Health Professional United States
Primary
Secondary
Juvenile Arthritis Death Female 66 lb 4/18/2011 Consumer Canada
Primary
Concomitant
Nausea Hospitalization 10/23/2008 17 Female 154 lb 4/18/2011 Lawyer United States
Primary
Concomitant
Death Hospitalization 4/1/2011 81 Male 149 lb 4/20/2011 Physician United States
Primary
Concomitant
Toxicity To Various Agents Death 53 Female 4/22/2011 Consumer United States
Primary
Secondary
Toxicity To Various Agents Death 53 Female 4/26/2011 Other Health Professional United States
Primary
Secondary
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 53 Female 5/4/2011 Consumer United States
Primary
Secondary
Sepsis Hospitalization 4/1/2011 81 Male 149 lb 5/6/2011 Physician United States
Primary
Concomitant
Pulmonary Hypoplasia Congenital Anomaly Male 3 lb 9/6/2011 Lawyer United States
Primary
Secondary
Concomitant
Sedation Hospitalization 67 Female 251 lb 9/16/2011 Other Health Professional Canada
Primary
Concomitant
Malignant Melanoma Death 2/20/2011 47 Female 174 lb 9/20/2011 Other Health Professional United States
Primary
Concomitant
Retinopathy Of Prematurity Other Serious Male 3 lb 9/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious 9/1/2011 65 Male 225 lb 11/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 1/1/2010 25 Female 12/21/2011 Physician United States
Primary
Secondary
Intentional Overdose Death 1/1/2010 19 Female 1/4/2012 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 8/18/2011 66 Male 239 lb 3/7/2012 Physician United States
Primary
Secondary
Concomitant
Kidney Malformation Other Serious 24 3/15/2012 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious 10/23/2011 72 Female 3/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Other Serious 10/23/2011 72 Female 4/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pain 3/15/2006 51 Male 160 lb 6/4/2012 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 3/15/2006 51 Male 160 lb 6/11/2012 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization Male 6/13/2012 Physician United States
Primary
Secondary
Concomitant
Drug Level Increased 3/15/2006 51 Male 160 lb 6/19/2012 Consumer United States
Primary
Secondary
Concomitant
Gait Disturbance 3/15/2006 51 Male 161 lb 7/23/2012 Physician United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 8/3/2011 16 Female 101 lb 11/15/2012 Physician Us
Primary
Concomitant
Wound Complication Hospitalization Female 10/15/2012 Physician Ca
Primary
Concomitant
Visual Impairment Hospitalization 7/15/2011 46 Female 9/26/2012 Other Health Professional Us
Primary
Concomitant
Wound Complication Other Serious 10/2011 72 Female 190 lb 3/7/2013 Physician Ca
Primary
Secondary
Concomitant
Colitis Ischaemic Other Serious 5/9/2012 72 Male 144 lb 11/26/2012 Physician Ca
Primary
Secondary
Concomitant
Rash Other Serious 8/20/2010 70 Female 135 lb 5/8/2013 Other Health Professional Ca
Primary
Concomitant
Reye's Syndrome Other Serious 15 Male 138 lb 9/28/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 8/25/2012 68 Male 9/19/2012 Other Health Professional Us
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/2012 Male 229 lb 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Myocardial Stunning Life Threatening 9/1/2012 18 Female 127 lb 5/21/2013 Physician Us
Primary
Secondary
Concomitant
Reye's Syndrome Hospitalization 15 Male 139 lb 9/13/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 8/22/2012 65 Female 191 lb 10/18/2012 Pharmacist Us
Primary
Concomitant
Troponin Increased Other Serious 9/20/2012 64 Male 119 lb 10/11/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 10/4/2012 59 Male 205 lb 11/20/2012 Consumer Us
Primary
Concomitant
Syncope Hospitalization 9/27/2012 18 Female 123 lb 11/13/2012 Physician Us
Primary
Concomitant
Vein Disorder Other Serious Female 10/29/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/6/2012 13 Female 2/15/2013 Physician Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 10/25/2012 24 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
Sepsis Death 8/6/2012 12 Female 10/18/2013 Physician Us
Primary
Secondary
Concomitant
Vascular Neoplasm Life Threatening 8/6/2012 12 Female Other Health Professional Us
Primary
Secondary
Concomitant
Sudden Death Hospitalization Male 187 lb 11/27/2012 Physician Us
Primary
Secondary
Concomitant
Product Solubility Abnormal Other Serious 11/30/2012 61 Male 131 lb 12/11/2012 Pharmacist Us
Primary
Concomitant
Post Procedural Haemorrhage Death 70 Male 207 lb 1/28/2013 Physician Ca
Primary
Concomitant
Poisoning Death 24 Female 12/10/2012 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 57 Female 1/9/2013 Physician Us
Primary
Secondary
Respiratory Disorder Death NotSpecified 1/9/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 57 Female 1/17/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 24 Female 1/16/2013 Other Health Professional Us
Primary
Secondary
Rhabdomyolysis 11/25/2012 36 Female 200 lb 1/10/2013 Physician Us
Primary
Concomitant
Completed Suicide Death 57 Female 1/18/2013 Physician Country Not Specified
Primary
Secondary
Completed Suicide Death 57 Female 1/20/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 77 Female 1/21/2013 Physician Us
Primary
Secondary
Spinal Compression Fracture Hospitalization 11/22/2011 83 Female 3/11/2013 Consumer Ca
Primary
Concomitant
Pancreatitis Hospitalization 12/2010 65 Female 1/28/2013 Physician Ca
Primary
Concomitant
Completed Suicide Death 57 Female 1/28/2013 Country Not Specified
Primary
Secondary
Hypervolaemia Hospitalization 1/16/2013 42 Female 227 lb 4/3/2013 Consumer Us
Primary
Concomitant
Hyperpyrexia 11/25/2012 36 Female 200 lb 2/5/2013 Physician Us
Primary
Concomitant
Death Death 57 Female 1/28/2013 Physician Us
Primary
Secondary
Malignant Neoplasm Progression Death Female 4/8/2013 Consumer Ca
Primary
Concomitant
Toxicity To Various Agents Death 2011 54 Male 1/18/2013 Other Health Professional Us
Primary
Secondary
Respiratory Arrest Death 2011 57 Female 1/17/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 2011 54 Male 1/18/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Completed Suicide Death 2011 57 Female 2/14/2013 Physician Us
Primary
Secondary
Completed Suicide Death 77 Female 2/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death 57 Female 2/18/2013 Physician Us
Primary
Secondary
Hypomagnesaemia Hospitalization 2/11/2013 17 Female 135 lb 3/7/2013 Physician Us
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 54 Male 1/25/2013 Country Not Specified
Primary
Secondary
Poisoning Death 54 Male 2/4/2013 Other Health Professional Us
Primary
Secondary
Respiratory Arrest Death 2011 57 Female 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 57 Female 1/31/2013 Physician Us
Primary
Secondary
Pyrexia Hospitalization 3/29/2013 60 Male 187 lb 4/1/2013 Physician Country Not Specified
Primary
Concomitant
Syncope Other Serious 4/2/2013 15 Female 6/14/2013 Consumer Us
Primary
Secondary
Concomitant
Septic Shock Hospitalization 4/13/2013 24 Male 210 lb 4/30/2013 Other Health Professional Ca
Primary
Concomitant
Urinary Glycosaminoglycans Increased Hospitalization 8/2012 0 Male 13 lb 5/2/2013 Consumer Us
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 4/25/2013 67 Female 270 lb 5/8/2013 Pharmacist Us
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 80 Female 5/2/2013 Physician Ca
Primary
Secondary
Concomitant

Drug Data