Acetaminophen combined with Hydromorphone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Death Death 3/2/2006 Female 3/15/2006 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/27/2006 80 Female 175 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/27/2006 80 Female 175 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/10/2005 68 Female 112 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 6/21/2005 65 Female 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/10/2005 68 Female 112 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Required Intervention 12/13/2005 53 Male 169 lb 3/1/2006 United States
Primary
Concomitant
Pseudomonas Infection Hospitalization 4/9/2006 55 Male 203 lb 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia 12/1/2005 67 Female 4/6/2006 Consumer United States
Primary
Concomitant
Rash Erythematous Death 3/11/2006 64 Male 5/22/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Incontinence Hospitalization 2/27/2006 80 Female 175 lb 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Substance Abuse Other Serious 11/8/2002 46 Female 102 lb 7/17/2006 Other Health Professional United States
Primary
Secondary
Accidental Overdose Death 3/9/2001 44 Male 176 lb 7/17/2006 Consumer United States
Primary
Secondary
Accidental Overdose Death 12/27/2000 29 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Urticaria Required Intervention 15 Female 8/31/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 50 Female 9/14/2006 Physician United States
Primary
Secondary
Nausea Hospitalization 8/7/2006 59 Female 157 lb 8/31/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/30/2006 59 Female 157 lb 8/29/2006 Consumer United States
Primary
Secondary
Concomitant
Sensation Of Pressure Hospitalization 8/21/2006 59 Female 152 lb 9/1/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Dyspnoea Hospitalization 8/7/2006 45 Female 105 lb 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Phlebitis 10/12/2006 24 Female 130 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/26/2005 86 Female 119 lb 11/8/2006 United States
Primary
Secondary
Throat Tightness Life Threatening 7/22/2006 35 Male 214 lb 12/15/2006 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/23/2006 36 Female 1/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Throat Tightness Other Serious 11/20/2006 51 Male 226 lb 11/24/2006 Pharmacist United States
Primary
Concomitant
Rash Generalised Other Serious 2/7/2007 35 Female 101 lb 2/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death Female 3/30/2007 Pharmacist United States
Primary
Secondary
Loss Of Consciousness Required Intervention 4/11/2007 35 Male 240 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 56 Female 6/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxicologic Test Abnormal Other Serious 9/15/2006 26 Female 150 lb 6/11/2007 United States
Primary
Secondary
Concomitant
Substance Abuse Other Serious 10/27/2006 23 Female 117 lb 5/24/2007 Physician United States
Primary
Secondary
Theft Other Serious 9/15/2006 26 Female 150 lb 6/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 9/15/2006 26 Female 6/27/2007 United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/13/2007 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 10/16/2006 Male 7/23/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/25/2007 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Life Threatening 10/16/2006 Male 7/31/2007 Physician United States
Primary
Concomitant
Serum Sickness Hospitalization 8/23/2006 53 Male 277 lb 1/15/2007 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 44 Female 7/31/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 8/7/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2006 79 Male 8/9/2007 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 10/16/2006 Male 8/20/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2006 79 Male 8/27/2007 Other Health Professional Canada
Primary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/1/2007 59 Male 187 lb 10/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 Female 150 lb 12/20/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Death 23 Female 136 lb 1/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 48 Male 1/15/2008 Physician United States
Primary
Secondary
Sepsis Death 10/30/2007 31 Female 162 lb 1/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 1/26/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/6/2007 Female 150 lb 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 11/21/2006 88 Female 2/5/2008 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 Female 150 lb 2/4/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2007 35 Male 151 lb 2/5/2008 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2006 28 Female 2/21/2008 Physician United States
Primary
Secondary
Treatment Noncompliance Other Serious 47 Male 243 lb 3/6/2008 Canada
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 7/23/2006 36 Female 3/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 3/19/2008 Physician United States
Primary
Secondary
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 81 Female 110 lb 4/11/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/6/2007 Female 150 lb 4/24/2008 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 4/13/2008 77 Female 5/1/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Prealbumin Decreased Other Serious 10/18/2006 50 Female 220 lb 5/28/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death Female 80 lb 6/6/2008 Consumer United States
Primary
Concomitant
Drug Toxicity Other Serious 58 Male 6/9/2008 Physician Canada
Primary
Secondary
International Normalised Ratio Increased Other Serious 10/20/2006 50 Female 6/11/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2007 Male 7/10/2008 Other Health Professional United States
Primary
Concomitant
Abdominal Abscess Hospitalization 7/19/2008 45 Male 143 lb 8/1/2008 Other Health Professional United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 8/19/2008 Lawyer United States
Primary
Concomitant
Pharmaceutical Product Complaint Death 4/10/2008 67 Female 8/22/2008 Lawyer United States
Primary
Concomitant
Abdominal Abscess Life Threatening 7/19/2008 45 Male 143 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Abscess Hospitalization 7/19/2008 45 Male 143 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/10/2008 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 9/10/2008 Lawyer United States
Primary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/19/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/1/2006 56 Male 9/24/2008
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/28/2008 9/16/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/30/2007 19 Male 9/29/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 56 Male 10/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/20/2008
Primary
Secondary
Concomitant
No Adverse Event 56 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/27/2008 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/1/2006 56 Male 10/29/2008
Primary
Secondary
Concomitant
Product Quality Issue Death 4/10/2008 67 Female 8/22/2008 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/14/2006 Female 132 lb 10/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 56 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 11/12/2008 United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/1/2008 69 Female 11/17/2008 United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 9/24/2008 Male 176 lb 11/19/2008 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/11/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/30/2007 19 Male 11/26/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 58 Male 1/6/2009 Physician Canada
Primary
Secondary
Completed Suicide Death 40 Female 1/13/2009 United States
Primary
Secondary
Completed Suicide Other Serious 1/23/2009 Other Health Professional United States
Primary
Secondary
Urticaria Hospitalization 15 Male 101 lb 1/23/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Splenomegaly Other Serious 12/1/2006 Male 1/29/2009 Lawyer United States
Primary
Concomitant
Neoplasm Progression Death Male 122 lb 2/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 11/13/2008 Female 3/12/2009 Physician Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 75 Female 183 lb 3/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death 78 Female 3/17/2009 Physician United States
Primary
Secondary
Nosocomial Infection Hospitalization 3/3/2009 45 Female 153 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 3/7/2009 81 Male 161 lb 3/10/2009 Pharmacist United States
Primary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Post Procedural Bile Leak Other Serious 1/1/2003 38 Female 293 lb 7/14/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 143 lb 7/27/2009 United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 2/1/2009 Female 7/28/2009 Physician Canada
Primary
Concomitant
Failure To Thrive Hospitalization Male 7/30/2009 Pharmacist
Primary
Concomitant
Oedema Peripheral Hospitalization 7/20/2009 Male 190 lb 7/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 80 Female 8/5/2009
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/7/2009 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/20/2009 Male 190 lb 7/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/20/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/13/2009 24 Female 289 lb 8/19/2009 Pharmacist United States
Primary
Concomitant
Respiratory Rate Increased Disability 8/26/2009 78 Female 96 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 9/2/2009 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 9/2/2009 United States
Primary
Concomitant

Drug Data