Acetaminophen combined with Fentanyl Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 10/26/2005 44 Female 2/6/2006 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 11/22/2005 73 Female 2/8/2006 United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 79 Female 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 1/25/2006 85 Male 2/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Death 1/1/1998 3/8/2006 United States
Primary
Secondary
Retroperitoneal Haematoma Hospitalization 4/30/2006 73 Male 7/5/2006 Pharmacist United States
Primary
Concomitant
Shock Death 11/23/2005 46 Male 8/30/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Urticaria Required Intervention 15 Female 8/31/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Thrombocythaemia Other Serious 10/16/2006 71 Male 11/9/2006 Other Health Professional Turkey
Primary
Concomitant
Completed Suicide Death 1/1/2005 45 11/17/2006 Physician United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/1/2006 56 Female 146 lb 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/25/2006 56 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Medication Error Other Serious 6/21/2003 Female 6 lb 1/4/2007 Consumer United States
Primary
Concomitant
White Blood Cell Disorder Hospitalization 11/8/2006 74 Male 1/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Stenotrophomonas Infection Hospitalization 12/14/2006 79 Female 1/29/2007 Taiwan, Province Of China
Primary
Concomitant
Death Death 1/1/2005 45 Unknown 2/7/2007 Physician United States
Primary
Secondary
Death Death 1/1/2004 34 3/21/2007 Pharmacist United States
Primary
Secondary
Tachycardia Hospitalization 7/25/2006 Female 4/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 56 Female 146 lb 4/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization Male 264 lb 4/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/25/2006 56 Female 4/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/3/2007 2 Female 13 lb 4/13/2007 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 4/17/2007 47 Male 129 lb 4/27/2007 Physician Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 4/17/2007 47 Male 129 lb 5/4/2007 Physician Canada
Primary
Concomitant
Psychotic Disorder Hospitalization Male 264 lb 7/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 7/13/2007 79 Female 186 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/12/2007 47 Male 129 lb 11/30/2007 Other Health Professional Canada
Primary
Concomitant
Pulse Absent Hospitalization 1/4/2008 0 Male 7 lb 1/29/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2003 54 2/6/2008 Physician Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2004 37 2/6/2008 Physician Canada
Primary
Secondary
Drug Toxicity Death 1/1/2004 37 2/6/2008 Physician Canada
Primary
Secondary
Drug Toxicity Death 1/1/2003 54 2/6/2008 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/22/2008 61 Male 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 76 Female 3/31/2008 Physician United States
Primary
Secondary
Concomitant
Paradoxical Pain Other Serious 76 Female 4/3/2008 Physician United States
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 12/14/2006 79 Female 4/28/2008 Taiwan, Province Of China
Primary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/11/2008 Female 117 lb 5/6/2008 United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 7/1/2005 55 Female 132 lb 7/17/2008 United Kingdom
Primary
Concomitant
Interacting
No Adverse Event 55 Female 132 lb 7/18/2008 United Kingdom
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 7/18/2008 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 5/11/2008 70 Male 110 lb 10/17/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 79 Female 10/20/2008 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 79 Female 10/21/2008 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Distress Other Serious 7/19/2008 63 Male 152 lb 10/22/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 56 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
No Adverse Event 56 Male 10/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 56 Male 10/27/2008 United Kingdom
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 56 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Somnolence Hospitalization 10/20/2008 1/21/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 6/1/2008 58 Male 1/21/2009 Netherlands
Primary
Concomitant
Shock Other Serious 11/23/2008 76 Male 185 lb 1/9/2009 Other Health Professional Canada
Primary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Intravascular Haemolysis Life Threatening 12/22/2008 68 Male 176 lb 1/26/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 12/10/2008 70 Male 1/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 12/1/2006 Male 1/29/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2007 58 Male 214 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 60 Male 3/3/2009 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 4/17/2002 38 Female 231 lb 4/21/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Pneumonia Necrotising Hospitalization 6/22/2008 71 Female 117 lb 5/27/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 7/1/2009 70 Female 99 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Life Threatening 7/7/2009 44 Female 7/16/2009 France
Primary
Secondary
Concomitant
Vasodilatation Death 1/25/2008 65 Male 8/4/2009 Lawyer United States
Primary
Concomitant
Visual Field Defect Life Threatening 7/7/2009 44 Female 8/12/2009 France
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Death 6/30/2007 Male 185 lb 11/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 8/5/2007 Female 11/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritoneal Haemorrhage Other Serious 10/2/2007 85 Female 11/19/2009 Lawyer United States
Primary
Concomitant
Drug Toxicity Death 6/30/2007 Male 185 lb 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 Female 154 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Telangiectasia Other Serious 75 Female 1/4/2010 Physician United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Female 2/19/2010 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 52 Female 180 lb 2/27/2010 Consumer United States
Primary
Concomitant
Drug Toxicity Death 23 Female 143 lb 2/28/2010 Physician United States
Primary
Concomitant
Drug Toxicity Death 62 Female 2/28/2010 Consumer United States
Primary
Secondary
Thrombocytopenia Other Serious 10/1/2007 85 Female 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 58 Male 214 lb 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Somnolence Death 51 Female 3/9/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/20/2007 48 Female 132 lb 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Overdose Death 43 Female 4/13/2010 Physician United States
Primary
Concomitant
Interacting
Off Label Use Death 8/17/2007 50 Male 150 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Death 8/17/2007 50 Male 150 lb 4/28/2010 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Death 53 Male 282 lb 5/3/2010 Consumer United States
Primary
Secondary
Vasodilatation Other Serious 1/1/2007 65 Male 121 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Off Label Use Death 8/17/2007 50 Male 150 lb 5/11/2010 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/19/2010 66 Male 351 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2007 58 Male 214 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 7/7/2009 44 Female 5/11/2010 France
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Female 176 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/20/2007 48 Female 132 lb 5/13/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/19/2010 66 Male 351 lb 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Female 7/6/2010 Physician United States
Primary
Secondary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2010 52 Male 238 lb 7/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Swollen Tongue Other Serious 5/1/2008 59 Male 194 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death 1/19/2008 17 Male 220 lb 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/20/2010 82 Male 8/3/2010 Consumer France
Primary
Concomitant
Ventricular Fibrillation Life Threatening 11/9/2009 75 Male 176 lb 8/4/2010 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/24/2010 65 Male 263 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2008 65 Male 258 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Overdose Death 43 Female 8/16/2010 Physician United States
Primary
Concomitant
Overdose Death 49 Male 8/16/2010 Physician United States
Primary
Secondary
Concomitant
Overdose Death 49 Male 8/16/2010 Physician United States
Primary
Secondary
Concomitant
Overdose Death 18 Male 8/16/2010 Physician United States
Primary
Concomitant
Overdose Death 43 Female 8/16/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2008 31 Female 284 lb 8/17/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 187 lb 8/19/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 72 Female 8/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 72 Female 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 16 Female 106 lb 8/16/2010 United Kingdom
Primary
Concomitant
Uterine Leiomyoma Other Serious Female 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Burning Sensation 8/11/2010 57 Female 70 lb 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 8/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2007 76 Male 8/26/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 4/8/2003 55 Female 181 lb 8/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 67 Female 218 lb 8/26/2010 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 8/26/2010 Lawyer United States
Primary
Concomitant

Drug Data