Acetaminophen combined with Diphenhydramine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash 11/10/2005 53 Male 156 lb 1/12/2006 Consumer United States
Primary
Concomitant
Eosinophilia 1/1/2005 36 224 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 49 Female 1/19/2006 Physician United States
Primary
Concomitant
Rash Macular Other Serious 9/4/2005 77 Female 194 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/25/2004 56 Female 106 lb 1/18/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 39 Male 1/19/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/6/2006 50 Male 110 lb 1/19/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/26/2006 41 Female 137 lb 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/2003 14 Male 2/14/2006 Other Health Professional United States
Primary
Secondary
Tremor Hospitalization 38 Female 2/7/2006 Pharmacist United States
Primary
Secondary
Retinopathy Hypertensive Disability 5/19/2005 63 Female 114 lb 2/23/2006 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 3/7/2006 36 Male 132 lb 3/9/2006 United States
Primary
Concomitant
Urticaria Other Serious 3/15/2006 Female 116 lb 3/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 47 Male 3/27/2006 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/17/2006 Female 210 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 1/1/1987 17 Female 4/18/2006 Physician United States
Primary
Secondary
Granulocytopenia Required Intervention 10/24/2005 79 Female 2/13/2006 United States
Primary
Concomitant
Insomnia 3/31/2006 69 Male 225 lb 7/12/2006 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/30/2006 57 Male 149 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/15/2006 68 Male 148 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious Male 8/1/2006 Other Health Professional United States
Primary
Concomitant
Eczema 1/1/2005 Female 8/29/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 7/21/2006 6 Female 47 lb 8/22/2006 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 7/11/2006 71 Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/28/2006 55 Male 228 lb 9/1/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Multi-organ Failure Death 48 Male 9/13/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 36 Female 9/13/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 2/28/2008 Male 212 lb 3/13/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2008 34 Male 141 lb 4/1/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 5/23/2007 7 Female 47 lb 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Sickness Hospitalization 7/6/2007 34 Female 4/4/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/22/2008 Male 167 lb 12/11/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 58 Male 12/24/2008 Physician United States
Primary
Secondary
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolysis Life Threatening 3/12/2009 Male 50 lb 3/17/2009 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 3/27/2009 Physician United States
Primary
Concomitant
Cardiovascular Disorder Death 3/31/2009 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Death 4/1/2009 Physician United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 59 Female 4/2/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 1/1/2006 40 Male 4/3/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/13/2007 Male 24 lb 4/3/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/7/1999 40 Male 210 lb 4/3/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Hypovolaemia Hospitalization 9/12/2008 76 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 9/12/2008 76 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 18 Female 10/8/2009 Other Health Professional United States
Primary
Concomitant
Xanthochromia Hospitalization 18 Female 10/16/2009 Physician United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 10/28/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/19/2008 20 Male 174 lb 10/28/2009 Lawyer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Eruption Other Serious 2 Male 10/30/2009 Other Health Professional South Africa
Primary
Secondary
Drug Toxicity Death 8/5/2007 Female 11/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Personality Change Required Intervention 12/23/2008 Female 90 lb 8/29/2009 Pharmacist United States
Primary
Concomitant
Hyperhidrosis Other Serious 10/13/2009 65 Male 147 lb 10/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death Female 155 lb 11/6/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death Female 157 lb 11/6/2009 Consumer United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 66 Male 180 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 12/16/2009 Other Health Professional United States
Primary
Concomitant
Serum Sickness Other Serious 2/1/2009 47 Female 108 lb 12/11/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 57 Female 1/11/2010 Other Health Professional United States
Primary
Secondary
Urticaria Other Serious 7/23/2009 Female 1/13/2010 Physician United States
Primary
Concomitant
Drug Toxicity Death 47 Female 1/19/2010 Other Health Professional Germany
Primary
Secondary
Drug Toxicity Death 33 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Drug Toxicity Death 41 Female 1/22/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 47 Female 1/23/2010 Other Health Professional United States
Primary
Secondary
Inadequate Analgesia Death 8/5/2007 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 30 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 57 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 29 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 47 Female 1/25/2010 Other Health Professional Germany
Primary
Secondary
Drug Toxicity Death 21 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 31 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Swollen Tongue Other Serious 1/19/2008 20 Male 174 lb 2/1/2010 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 11/27/2007 58 Female 123 lb 2/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 58 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 9/29/2009 47 Female 2/5/2010 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 44 Female 2/5/2010 Other Health Professional Canada
Primary
Secondary
Inadequate Analgesia Death 8/5/2007 Female 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Obstruction Other Serious 2/11/2010 United States
Primary
Concomitant
Neoplasm Malignant Other Serious 2/11/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/11/2010 United States
Primary
Concomitant
Respiratory Distress Other Serious 36 Female 2/12/2010 Other Health Professional United States
Primary
Concomitant
Poisoning Deliberate Death 1/1/2008 47 Female 2/2/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 30 Female 2/2/2010 Physician United States
Primary
Secondary
Hypovolaemia Hospitalization 9/12/2008 76 Female 178 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/17/2010 United States
Primary
Concomitant
Neoplasm Malignant Other Serious 2/17/2010 United States
Primary
Concomitant
Cardiac Arrest Death 59 Male 2/18/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 26 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Oral Pain Hospitalization 1/14/2010 69 Male 174 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Obstruction Other Serious 2/22/2010 United States
Primary
Concomitant
Completed Suicide Death 41 Male 2/22/2010 United States
Primary
Secondary
Death Death 50 Female 2/22/2010 United States
Primary
Secondary
Intentional Drug Misuse Death 31 Female 2/22/2010 United States
Primary
Secondary
Multi-organ Failure Death 41 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 24 Male 2/23/2010 United States
Primary
Secondary
Overdose Death 71 Female 105 lb 2/26/2010 Physician United States
Primary
Concomitant
Drug Abuse Death 39 Male 198 lb 3/1/2010 Consumer United States
Primary
Concomitant
Drug Toxicity Death Female 130 lb 3/1/2010 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 3/21/2004 53 Female 187 lb 3/1/2010 Physician United States
Primary
Secondary
Hypovolaemia Hospitalization 9/12/2008 76 Female 178 lb 3/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 9/12/2008 76 Female 178 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/14/2005 52 Male 150 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 4/30/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2007 58 Female 5/3/2010 Lawyer United States
Primary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Vasodilatation Other Serious 1/1/2007 65 Male 121 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Right Ventricular Dysfunction Hospitalization 1/28/2010 36 Female 157 lb 5/4/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/16/2010 69 Female 210 lb 5/5/2010 Pharmacist United States
Primary
Concomitant
Palpitations Hospitalization 4/14/2010 79 Female 145 lb 5/7/2010 Consumer United Kingdom
Primary
Concomitant
Product Quality Issue Other Serious 4/28/2010 Female 5/10/2010 Consumer United States
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Oedema Peripheral Other Serious 9/29/2009 47 Female 5/11/2010 Consumer United States
Primary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 1/1/2010 81 Male 128 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 5/17/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Other Serious 1/1/2007 26 Male 141 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 28 Female 209 lb 5/25/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 5/25/2010 Consumer Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 5/27/2010 56 Female 224 lb 6/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 6/11/2010 Consumer Japan
Primary
Concomitant
Neuropathy Peripheral Other Serious 6/15/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Splenic Marginal Zone Lymphoma Death 6/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Splenic Marginal Zone Lymphoma Death 6/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Oedema Disability 8/11/2009 32 Female 110 lb 6/17/2010 Consumer United Kingdom
Primary
Concomitant
Overdose Hospitalization 28 Male 6/18/2010 United States
Primary
Secondary

Drug Data