Acetaminophen combined with Diphenhydramine Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious 7/15/2004 Male 2/21/2006 Physician Japan
Primary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/21/2006 United States
Primary
Concomitant
Vomiting Hospitalization 3/3/2003 86 Female 121 lb 2/22/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Disability 2/25/2006 Female 132 lb 3/9/2006 United States
Primary
Concomitant
Protein Total Decreased Other Serious 7/15/2004 Male 3/14/2006 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Nausea Hospitalization 6/21/2005 65 Female 4/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/1/2006 76 Male 8/8/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/1/2006 76 Male 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Death 67 Female 10/23/2006 Physician United States
Primary
Concomitant
Peritonitis Death 72 Male 10/23/2006 Physician United States
Primary
Concomitant
Respiratory Failure Death Male 193 lb 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/25/2007 59 Male 193 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/1/2006 76 Male 8/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 38 Female 9/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Drug Level Increased Death 7/26/2007 56 Male 168 lb 11/26/2007 Other Health Professional United States
Primary
Concomitant
Drug Level Increased Death 7/26/2007 56 Male 168 lb 12/3/2007 Other Health Professional United States
Primary
Concomitant
Overdose Death 43 Male 1/7/2008 Physician United States
Primary
Secondary
Death Death 56 Female 1/21/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 Female 3/7/2008 United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 3/31/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/15/2007 65 Male 194 lb 5/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2008 71 Female 152 lb 5/14/2008 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 4/17/2007 Female 185 lb 5/22/2008 United States
Primary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Respiratory Failure Death Male 193 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 8/15/2007 65 Male 194 lb 7/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/25/2007 Male 193 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 8/1/2006 77 Male 7/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 6/19/2008 Female 150 lb 7/21/2008 United States
Primary
Concomitant
Vomiting Hospitalization 3/17/2008 71 Female 152 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Neonatal Other Serious 8/1/2006 7/22/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 7/31/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2008 71 Female 152 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Drug Level Increased Other Serious 7/26/2007 56 Male 168 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 9/8/2008 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/18/2008 75 Male 226 lb 9/9/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2008 71 Female 152 lb 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/29/2008 71 Female 152 lb 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 9/20/2008 Female 10/10/2008 United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/22/2004 Female 161 lb 10/17/2008 Canada
Primary
Concomitant
Heart Rate Increased Other Serious 9/20/2008 Female 10/17/2008 United States
Primary
Concomitant
Parvovirus B19 Serology Positive Other Serious 3/27/2008 Female 10/27/2008 Consumer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/22/2004 Female 161 lb 10/27/2008 Canada
Primary
Concomitant
Suicide Attempt Hospitalization 10/27/2008 Female 198 lb 10/29/2008 Physician Germany
Primary
Secondary
Stenotrophomonas Infection Hospitalization 9/25/2008 61 Male 235 lb 10/23/2008 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/22/2004 Female 161 lb 10/30/2008 Canada
Primary
Concomitant
Death Death 32 Female 10/31/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/20/2008 78 Male 216 lb 10/31/2008 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/22/2004 Female 161 lb 11/14/2008 Canada
Primary
Concomitant
Tachycardia Hospitalization 10/27/2008 Female 198 lb 11/18/2008 Physician Germany
Primary
Secondary
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 11/18/2008 Consumer United States
Primary
Concomitant
Stenotrophomonas Infection Hospitalization 9/25/2008 61 Male 235 lb 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 11/7/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 213 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 11/14/2008 United States
Primary
Secondary
Concomitant
Skin Discolouration Disability 2/25/2006 Female 132 lb 12/1/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 213 lb 11/24/2008 United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/28/2008 65 Male 207 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 4 Female 37 lb 11/7/2008 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2007 59 Male 193 lb 12/18/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 32 Female 12/24/2008 Physician United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 6/1/2008 Female 178 lb 1/7/2009 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 6/15/2006 Female 204 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Agranulocytosis Other Serious 2/26/2009 63 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 2/20/2009 32 Female 122 lb 4/10/2009 Physician United States
Primary
Concomitant
Intestinal Perforation Hospitalization 4/1/2009 65 Female 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Operation Hospitalization 3/24/2009 51 Female 6/1/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 207 lb 6/9/2009 United States
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 5/14/2008 71 Male 7/1/2009 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/1/2008 Female 178 lb 7/22/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 65 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 70 Male 9/3/2009 Physician United States
Primary
Secondary
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 10/3/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Male 11/3/2009 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/6/2008 78 Male 207 lb 10/27/2009 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/6/2008 78 Male 207 lb 10/30/2009 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/18/2008 75 Male 225 lb 11/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/29/2008 71 Female 134 lb 11/13/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 70 Male 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/12/2006 Male 194 lb 2/9/2010 Consumer France
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Completed Suicide Death 34 Female 2/26/2010 Physician Denmark
Primary
Secondary
Completed Suicide Death 29 Female 2/26/2010 Other Health Professional Denmark
Primary
Secondary
Hypersensitivity Other Serious 9/13/2005 Female 3/10/2010 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 Male 3/16/2010 Physician Japan
Primary
Concomitant
Serum Sickness Other Serious 3/16/2010 Consumer United Kingdom
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 3/2/2010 78 Female 113 lb 3/15/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Hospitalization 3/10/2010 Male 34 lb 3/22/2010 Physician United States
Primary
Concomitant
Serum Sickness Other Serious Female 3/22/2010 Consumer United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 3/11/2010 78 Female 92 lb 3/12/2010 Pharmacist United States
Primary
Concomitant
Oral Pain Hospitalization 1/14/2010 69 Male 174 lb 3/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 3/10/2010 Male 34 lb 3/31/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/1/2010 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 9/19/2009 17 Male 198 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Mental Impairment Other Serious 1/1/2009 23 Male 287 lb 4/6/2010 Consumer Canada
Primary
Concomitant
Cerebral Haemorrhage Death 1/20/2010 81 Male 4/8/2010 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 4/9/2010 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/20/1998 88 Female 4/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 4/13/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 4/13/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Overdose Death 43 Female 4/13/2010 Physician United States
Primary
Concomitant
Interacting
Syncope Hospitalization 7/1/2009 53 Male 232 lb 4/14/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 54 Female 232 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 22 Male 126 lb 4/20/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 12/3/2008 72 Male 194 lb 4/21/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 57 Male 151 lb 4/26/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2010 33 Male 99 lb 5/7/2010 Physician Japan
Primary
Concomitant
Somnolence Other Serious 11/25/2009 82 Male 187 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/28/2010 33 Male 99 lb 5/25/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 1/1/2008 28 Female 209 lb 5/26/2010 Physician United States
Primary
Concomitant
Keratitis Interstitial Other Serious 9/13/2005 12 Female 5/27/2010 United States
Primary
Concomitant
Ocular Icterus Other Serious 1/1/2006 64 Female 6/1/2010 Consumer United States
Primary
Concomitant
Gastric Cancer Death 6/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 5/28/2010 93 Female 179 lb 5/29/2010 Pharmacist United States
Primary
Concomitant
Coronary Artery Dilatation Hospitalization 5/19/2010 1 Male 26 lb 6/2/2010 Physician United States
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 5/8/2010 56 Male 137 lb 5/31/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 73 Female 5/28/2010 United States
Primary
Concomitant
Hyponatraemia Death 6/4/2010 United States
Primary
Secondary
Concomitant
No Adverse Event Hospitalization 12/1/2009 33 Female 6/7/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 14 Male 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Death 6/8/2010 United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 9/1/2008 74 Male 115 lb 6/8/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 3/1/2010 50 Female 128 lb 6/15/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Retinitis Other Serious 2/11/2010 67 Female 99 lb 6/17/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 2/1/2010 71 Female 113 lb 6/17/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 61 Male 6/22/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 5/12/2010 68 Female 185 lb 7/29/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 1/23/2010 72 Female 143 lb 8/4/2010 Consumer Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2010 65 Female 171 lb 8/10/2010 Physician United States
Primary
Concomitant

Drug Data