Acetaminophen combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Perforated Ulcer Other Serious 73 154 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Other Serious 5/31/2001 47 Male 165 lb 1/26/2006 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 11/11/2004 88 Female 1/24/2006 United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/1/2003 4 Female 22 lb 10/6/2005 Physician France
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 1/1/2006 84 Male 2/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/5/2006 84 Male 2/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 1/2/2006 93 Female 88 lb 2/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/20/2006 Consumer France
Primary
Secondary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 1/5/2006 84 Male 2/16/2006 France
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/3/2005 84 Female 2/24/2006 Other Health Professional France
Primary
Concomitant
Peritonitis Hospitalization 6/19/2002 Female 110 lb 2/27/2006 Physician United Kingdom
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 12/8/2005 84 Female 2/10/2006 United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Nodal Rhythm Hospitalization 8/23/2005 58 Female 3/2/2006 Physician Australia
Primary
Secondary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Swelling Face Other Serious 3/20/2005 72 Male 278 lb 12/21/2005 Consumer United States
Primary
Concomitant
Hypocoagulable State Life Threatening 1/1/2004 72 Male 3/22/2006 Other Health Professional France
Primary
Concomitant
Interacting
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 3/17/2006 United States
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Convulsion Hospitalization 1/8/2005 82 Male 146 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Pain In Jaw Other Serious 2/1/2004 Female 179 lb 5/3/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2003 64 Female 154 lb 5/15/2006 Lawyer Canada
Primary
Concomitant
Drug Ineffective 1/1/2006 77 Male 5/5/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia Facial 50 Female 247 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/25/2006 79 Female 7/5/2006 Denmark
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/10/2006 81 Female 7/7/2006 France
Primary
Secondary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 5/1/2006 92 Female 112 lb 6/30/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 3/8/2006 84 Female 99 lb 7/3/2006 France
Primary
Concomitant
Anaemia Hospitalization 1/1/2006 7/18/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 4/24/2006 79 Male Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/10/2006 81 Female 7/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/18/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/25/2006 79 Female 7/27/2006 Denmark
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/19/2006 86 Female 8/4/2006 Pharmacist France
Primary
Concomitant
Weight Decreased 10/1/2005 74 Female 8/4/2006 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Somnolence Death 6/14/2006 89 8/2/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/1/2005 55 Female 8/9/2006 France
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/14/2006 89 Unknown 8/4/2006 United Kingdom
Primary
Concomitant
Tremor Disability 4/23/2005 87 Female 95 lb 8/14/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 65 Female 8/14/2006 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/26/2006 82 Female 8/24/2006 United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 12/27/2005 55 Female 8/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Pharyngolaryngeal Pain 16 Female 113 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Respiratory Tract Irritation 13 Female 154 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/5/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/8/2006 United States
Primary
Concomitant
Dysphagia Other Serious 71 Female 9/20/2006 Other Health Professional Germany
Primary
Concomitant
Foreign Body Trauma Hospitalization 71 Female 128 lb 9/22/2006 Physician Germany
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 64 Female 10/6/2006 Physician Australia
Primary
Concomitant
Hypoglycaemia Life Threatening 4/7/2006 Female 115 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Anaemia Hospitalization 1/1/2006 10/12/2006 Pharmacist Australia
Primary
Secondary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Staphylococcal Infection Hospitalization 3/10/2006 56 Female 140 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/25/2006 27 Female 224 lb 10/18/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 10/19/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/5/2006 96 Female 128 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 7/4/2006 87 Female 141 lb 11/7/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 9/1/2006 Male 172 lb 12/14/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 12/27/2006 Other Health Professional United States
Primary
Concomitant
Urine Flow Decreased 1/1/2005 85 Male 12/28/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2006 Female 1/5/2007 Physician Fiji
Primary
Secondary
Concomitant
Overdose Other Serious 11/30/2005 69 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Medication Error Other Serious 6/21/2003 Female 6 lb 1/4/2007 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/25/2006 87 Female 107 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 16 Female 113 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 4/1/2005 77 Male 150 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/2/2007 Other Health Professional United States
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 1/30/2007 Physician United States
Primary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 8/11/2006 72 Male 2/6/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/12/2007 Other Health Professional United States
Primary
Concomitant
Neuropathy Peripheral Disability 12/4/2006 94 Female 93 lb 2/23/2007 Consumer France
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/13/2007 Physician United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 2/15/2007 Physician Australia
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 10/20/2006 81 Female 168 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/23/2007 Physician United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 3/2/2007 Physician Australia
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 1/3/2006 80 Female 163 lb 3/22/2007 Pharmacist Spain
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 1/3/2006 80 Female 163 lb 3/23/2007 France
Primary
Secondary
Concomitant
Interacting
Vomiting Other Serious 10/1/2005 Male 180 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/24/2007 72 Male 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Lung Disorder 6/1/2006 19 Male 93 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Gangrene Required Intervention 2/3/2007 54 Male 241 lb 2/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/6/2007 79 Male 187 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 4/27/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 5/2/2007 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage 10/20/2006 Female 5/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 4/24/2007 Male 173 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2006 68 Female 5/18/2007 Sweden
Primary
Secondary
Concomitant
Haemorrhage Other Serious 3/15/2007 67 Male 218 lb 5/10/2007 Other Health Professional United States
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 69 Female 6/27/2007 Consumer Italy
Primary
Secondary
Skin Burning Sensation Hospitalization 3/16/2007 53 Female 126 lb 6/27/2007 Pharmacist United States
Primary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Tachypnoea Hospitalization 7/26/2007 79 Male 225 lb 8/3/2007 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2005 74 Male 230 lb 7/9/2007 United States
Primary
Concomitant
Nephritis Interstitial Hospitalization 7/13/2007 79 Female 186 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 8/11/2006 72 Male 8/18/2007 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2007 67 Male 174 lb 8/29/2007 Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2007 67 Male 174 lb 9/6/2007 Australia
Primary
Secondary
Concomitant
Back Pain 4/26/2007 70 Female 223 lb 9/20/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 7/6/2003 Female 167 lb 10/16/2007 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/3/2007 88 Female 10/24/2007 Physician Sweden
Primary
Secondary
Concomitant
Clostridial Infection Death 8/19/2007 92 Female 93 lb 10/29/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 8/3/2007 64 Male 11/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Traumatic Haematoma Other Serious 5/10/2007 79 Female 11/20/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 5/15/2007 79 Female 11/26/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 8/17/2007 84 Female 12/4/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/15/2006 73 Female 12/4/2007 Physician United States
Primary
Secondary
Concomitant
Ototoxicity Other Serious 9/7/2007 70 Male 167 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 7/1/2001 73 Male 183 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/3/2007 88 Female 1/25/2008 Physician Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/2/2007 79 Female 1/18/2008 France
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 67 Female 2/5/2008 Physician United States
Primary
Concomitant
Malaise Other Serious 8/1/2007 65 Female 229 lb 1/29/2008 Physician United States
Primary
Concomitant
Malaise Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 8/27/2007 Male 134 lb 2/13/2008 Other Health Professional France
Primary
Concomitant
Interacting
Hypothyroidism Hospitalization 11/19/2001 50 Male 1/24/2008 United States
Primary
Concomitant
Oropharyngeal Blistering Other Serious 1/7/2008 Male 161 lb 3/4/2008 Physician United Kingdom
Primary
Concomitant

Drug Data