Acetaminophen combined with Cyclobenzaprine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Required Intervention 5/5/2006 23 Female 7/12/2006 Pharmacist United States
Primary
Concomitant
Substance Abuse Death 7/4/2007 20 Male 144 lb 10/31/2007 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 20 Female 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 32 Female 10/30/2008 Physician United States
Primary
Secondary
Death Death 32 Female 10/31/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 53 Female 12/24/2008 Physician United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 56 Female 1/21/2009 Physician United States
Primary
Secondary
Multiple Drug Overdose Intentional Death 56 Female 2/10/2009 Physician United States
Primary
Secondary
Completed Suicide Death 53 Female 2/10/2009 Other Health Professional United States
Primary
Secondary
Arteriosclerosis Death 9/2/2000 41 Female 254 lb 2/6/2009 United States
Primary
Secondary
Respiratory Arrest Death 50 Female 2/13/2009 Physician United States
Primary
Secondary
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death 57 Female 2/26/2009 United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 53 Female 2/27/2009 United States
Primary
Secondary
Cardio-respiratory Arrest Death 50 Female 3/9/2009 Physician United States
Primary
Secondary
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Nightmare 4/17/2008 39 Male 165 lb 12/29/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 203 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Pruritus Other Serious 12/1/2003 43 Female 134 lb 5/20/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/21/2009 67 Male 218 lb 5/22/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 18 Female 242 lb 6/25/2009 United States
Primary
Concomitant
Respiratory Tract Infection Fungal Other Serious 1/17/2008 82 Female 203 lb 6/23/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 202 lb 6/30/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 202 lb 7/17/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Respiratory Distress Other Serious 1/17/2008 82 Female 202 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/3/2004 55 Female 220 lb 8/27/2009 United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 12/1/2003 65 Female 190 lb 9/14/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2004 43 Female 168 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Irritability 2/2/2007 42 Female 9/23/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 5/27/2003 28 Male 160 lb 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Other Serious Female 225 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 1/1/2005 38 Female 9/23/2009 United States
Primary
Concomitant
Drug Toxicity Other Serious 5/24/2009 46 Male 10/23/2009 Other Health Professional United States
Primary
Secondary
Weight Increased Other Serious 30 Male 226 lb 11/17/2009 United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2007 52 Male 180 lb 12/1/2009 Consumer United States
Primary
Concomitant
Poor Quality Sleep Hospitalization 1/1/2009 54 Female 12/10/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious Female 12/14/2009 United States
Primary
Concomitant
Drug Toxicity Death 46 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 46 Female 1/18/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious Female 1/13/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 48 Female 1/26/2010 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Other Serious 7/1/2006 36 Female 215 lb 1/29/2010 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Completed Suicide Death 39 Female 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 39 Female 2/22/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 59 Female 208 lb 2/27/2010 Physician United States
Primary
Secondary
Drug Toxicity Death Female 2/27/2010 Physician United States
Primary
Secondary
Dysuria 10/1/2008 53 Male 292 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Other Serious Female 3/17/2010 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 52 Male 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/12/2009 59 Female 77 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/13/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 4/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/7/2010 United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/12/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 10/12/2009 72 Female 5/13/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 5/19/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/19/2010 70 Female 170 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Drug Toxicity Death 52 Male 6/9/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Vomiting Hospitalization 10/18/2009 39 Female 197 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 11/17/2004 51 Female 180 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
International Normalised Ratio Increased 47 Female 227 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/3/2010 28 Female 7/13/2010 Other Health Professional United States
Primary
Secondary
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 4/3/2010 28 Female 7/22/2010 Other Health Professional United States
Primary
Secondary
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 7/29/2010 United States
Primary
Secondary
Concomitant
Pain Female 175 lb 7/29/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 75 Female 170 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious Female 8/5/2010 United States
Primary
Concomitant
Sepsis Other Serious 7/16/2010 8/9/2010 Other Health Professional United States
Primary
Secondary
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/13/2010 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 8/13/2010 United States
Primary
Concomitant
Overdose Death 49 Male 8/16/2010 Physician United States
Primary
Secondary
Concomitant
Overdose Death 49 Male 8/16/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 78 Female 155 lb 8/18/2010 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 7/1/2010 51 Female 188 lb 8/18/2010 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 11/17/2008 64 Female 176 lb 8/19/2010 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2003 46 Male 178 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious Female 8/27/2010 Other Health Professional Canada
Primary
Concomitant
Pulmonary Oedema Death 49 Male 8/20/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 9/8/2010 United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Vertebral Foraminal Stenosis Other Serious 11/17/2004 51 Female 180 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 286 lb 9/20/2010 United States
Primary
Concomitant
Chest Discomfort Hospitalization 9/12/2010 53 Female 170 lb 9/23/2010 Other Health Professional Canada
Primary
Concomitant
Scar Hospitalization 6/5/2010 40 Male 210 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Drug Eruption Other Serious 64 Female 9/20/2010 Physician United States
Primary
Concomitant
Thrombophlebitis Other Serious Female 10/8/2010 Other Health Professional Canada
Primary
Concomitant
Drug Toxicity Death 52 Male 10/25/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/26/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 57 Female 11/11/2010 United States
Primary
Concomitant
Insomnia 8/4/2010 66 Female 10/25/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 12/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 12/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Toxicity To Various Agents Death 38 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 37 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 70 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2009 70 Female 1/7/2011 Physician United States
Primary
Secondary
Abdominal Pain Upper Hospitalization 11/20/2006 25 Female 185 lb 1/10/2011 Consumer Ukraine
Primary
Secondary
Concomitant
Completed Suicide Death 38 Male 1/11/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 37 Male 1/13/2011 Other Health Professional United States
Primary
Secondary
Death Death 38 Male 1/13/2011 Physician United States
Primary
Secondary
Completed Suicide Death 70 Female 1/13/2011
Primary
Secondary
Completed Suicide Death 70 Female 1/19/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Male 1/21/2011 Physician United States
Primary
Secondary
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Toxicity To Various Agents Death 1/1/2009 70 Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Hypotension Other Serious 2/1/2008 75 Female 170 lb 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Death 68 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 38 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 37 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 70 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2009 70 Female 1/27/2011 Physician United States
Primary
Secondary

Drug Data