Acetaminophen combined with Carvedilol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/12/2005 78 Male 151 lb 12/30/2005 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Dizziness Hospitalization 11/2/2005 Male 166 lb 12/2/2005 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 2/18/2006 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 2/28/2006 United Kingdom
Primary
Concomitant
Temporal Arteritis Hospitalization 5/15/2004 73 Female 174 lb 4/5/2006 Physician Spain
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 10/30/2004 29 Female 121 lb 4/1/2006 United States
Primary
Concomitant
Dizziness Other Serious 9/13/2005 64 Male 209 lb 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 2/6/2006 55 Female 168 lb 4/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/9/2005 67 Female 7/5/2006 Switzerland
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 6/9/2006 70 Female 7/19/2006 Physician Spain
Primary
Concomitant
Vomiting Required Intervention 5/1/2005 Female 170 lb 11/3/2005 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 2/6/2006 77 Female 168 lb 8/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/26/2006 82 Female 8/24/2006 United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Post Procedural Complication Other Serious 12/12/2005 72 Female 132 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Abdominal Discomfort Other Serious 7/10/2006 78 Male 180 lb 7/10/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Life Threatening 4/7/2006 Female 115 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Required Intervention 8/23/2006 85 Male 160 lb 10/10/2006 Other Health Professional United States
Primary
Concomitant
Myositis Life Threatening 7/30/2006 79 Female 110 lb 10/25/2006 United Kingdom
Primary
Concomitant
Staphylococcal Infection Life Threatening 8/16/2006 54 Male 269 lb 10/27/2006 Physician Belgium
Primary
Concomitant
Troponin Increased Life Threatening 8/17/2006 54 Male 269 lb 11/3/2006 Physician Belgium
Primary
Concomitant
Staphylococcal Infection Life Threatening 8/17/2006 54 Male 269 lb 12/6/2006 Physician Belgium
Primary
Concomitant
Femur Fracture Hospitalization 11/21/2006 84 Female 12/21/2006 Other Health Professional Singapore
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Treatment Noncompliance Required Intervention 7/5/2006 77 Male 185 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/23/2006 52 Male 329 lb 10/13/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/18/2006 79 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Femur Fracture Hospitalization 11/21/2006 84 Female 3/8/2007 Other Health Professional Singapore
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Lung Disorder 6/1/2006 19 Male 93 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/12/2007 77 Male 7/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 7/13/2007 Other Health Professional Germany
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/5/2007 United States
Primary
Concomitant
Death Death 5/1/2007 Male 183 lb 9/11/2007 United States
Primary
Concomitant
Renal Impairment Hospitalization 11/8/2006 75 Male 10/9/2007 Physician Australia
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 11/2/2007 United States
Primary
Concomitant
Pain In Extremity Hospitalization 11/4/2007 61 Male 11/19/2007 Consumer United States
Primary
Secondary
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
Staphylococcal Infection Hospitalization 11/4/2007 61 Male 1/4/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 52 Female 1/22/2008 Physician United States
Primary
Secondary
Death Death 5/23/2007 Male 183 lb 2/5/2008 United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/1/2006 57 Female 2/12/2008 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 5/1/2007 60 Male 204 lb 3/17/2008 Physician Germany
Primary
Concomitant
Urinary Bladder Polyp Life Threatening 8/17/2006 Male 269 lb 3/28/2008 Belgium
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 2/2/2008 Female 179 lb 4/4/2008 Canada
Primary
Concomitant
Sudden Death Death 12/5/2007 48 Male 148 lb 4/3/2008 Physician Japan
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 36 Female 227 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/24/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 5/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Respiratory Arrest Death 5/1/2008 67 Male 5/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 5/29/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 6/2/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Disturbance 4/8/2008 Female 6/12/2008 United States
Primary
Secondary
Concomitant
Fatigue 5/10/2008 Male 174 lb 6/13/2008 United States
Primary
Concomitant
Skin Hypertrophy Hospitalization 2/17/2008 77 Female 6/13/2008 Consumer France
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/13/2008 70 Male 6/16/2008 Physician Philippines
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 183 lb 6/18/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/14/2005 78 Male 104 lb 7/2/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/30/2007 79 Female 7/16/2008 Other Health Professional Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 Female 176 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 Female 176 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 9/1/2007 76 Male 88 lb 8/1/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/30/2007 79 Female 8/13/2008 Other Health Professional Australia
Primary
Concomitant
Infusion Related Reaction Other Serious 7/29/2008 39 Male 8/12/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 Female 176 lb 8/25/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 5/15/2008 73 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 7/21/2008 Male 210 lb 8/27/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 9/5/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/1/2008 67 Male 9/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting 7/21/2008 Female 150 lb 9/12/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Hyperglycaemia Other Serious 7/29/2008 39 Male 9/16/2008 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/30/2007 19 Male 9/29/2008 Physician United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 5/15/2008 73 Female 119 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/9/2008 Male 10/27/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/9/2007 Male 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/30/2007 19 Male 11/26/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/24/2008 85 Female 12/8/2008 France
Primary
Secondary
Circulatory Collapse Other Serious 2 Female 12/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 2 Female 23 lb 12/15/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Circulatory Collapse Life Threatening 2 Female 23 lb 12/15/2008 Canada
Primary
Secondary
Concomitant
Electromechanical Dissociation Other Serious 2 Female 12/16/2008 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 52 Male 1/20/2009 Other Health Professional United States
Primary
Secondary
Chest Pain Hospitalization 3/14/2009 4/2/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/15/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/14/2005 78 Male 104 lb 4/10/2009 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 4/24/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Wheezing Other Serious 2/23/2008 1 Male 5/19/2009 Physician Brazil
Primary
Concomitant
Leukopenia Life Threatening 2/28/2009 84 5/29/2009 Physician Italy
Primary
Concomitant
Chest Pain Hospitalization 3/14/2009 73 6/9/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Wheezing Other Serious 2/23/2008 1 Male 6/11/2009 Physician Brazil
Primary
Concomitant
Ventricular Hypokinesia Other Serious 4/17/2009 1 Male 12 lb 6/11/2009 Physician Brazil
Primary
Concomitant
Ventricular Hypokinesia Other Serious 4/17/2009 1 Male 12 lb 6/22/2009 Physician Brazil
Primary
Concomitant
Weight Decreased Other Serious 4/1/2009 Male 213 lb 7/8/2009 Physician United States
Primary
Concomitant
Death Death 7/1/2009 Female 7/9/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 7/1/2009 Female 7/23/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/30/2009 75 Male 216 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 52 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 52 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 9/7/2008 53 Male 243 lb 8/12/2009 United States
Primary
Concomitant
Electromechanical Dissociation Required Intervention 2 Female 23 lb 9/3/2009 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 3/1/2009 67 Male 137 lb 9/22/2009 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Somnolence 7/1/2009 76 Male 9/10/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Death Death Male 245 lb 10/19/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 52 Female 10/12/2009 United States
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/2/2009 Australia
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Death 10/23/2009 75 Male 287 lb 12/1/2009 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 11/23/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 76 Female 198 lb 12/11/2009 United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 3/5/2009 76 Male 168 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 8/1/2008 48 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 73 Female 12/23/2009 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 12/21/2009 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 1/4/2010 68 Female 184 lb 1/14/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Infarction Life Threatening 1/9/2010 Male 95 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/31/2009 91 Male 148 lb 1/5/2010 Pharmacist United States
Primary
Concomitant
Proteinuria Hospitalization 1/4/2010 68 Female 184 lb 2/2/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Increased Hospitalization 65 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant

Drug Data