Acetaminophen combined with Carbamazepine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder 44 Female 1/5/2006 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Life Threatening 37 Female 1/26/2006
Primary
Secondary
Death Death 8 Female 2/6/2006 Pharmacist United States
Primary
Secondary
Pregnancy Test Urine Positive Required Intervention 2/1/2006 22 Female 2/7/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/24/2006 27 Male 105 lb 2/8/2006 United States
Primary
Concomitant
Poor Venous Access Life Threatening 37 Female 2/6/2006
Primary
Secondary
Weight Decreased Other Serious 3/1/2005 38 Male 133 lb 2/23/2006 Physician United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 1/25/2006 86 Female 99 lb 2/24/2006 United Kingdom
Primary
Secondary
Concomitant
Pregnancy Required Intervention 2/1/2006 22 Female 2/17/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/27/2006 72 Male 2/22/2006 Japan
Primary
Concomitant
Weight Decreased Other Serious 3/1/2005 38 Male 133 lb 3/1/2006 Physician United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/24/2006 27 Male 105 lb 3/3/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2005 38 Male 133 lb 3/13/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 3/1/2005 38 Male 133 lb 3/23/2006 Physician United Kingdom
Primary
Concomitant
Death Death 11/21/2005 Male 128 lb 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 1/27/2006 72 Male 3/27/2006 Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 Male 209 lb 5/8/2006 Lawyer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 Male 209 lb 5/10/2006 Lawyer Canada
Primary
Concomitant
Tremor Hospitalization 12/1/2005 82 Female 5/11/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tremor Other Serious 11/1/2005 82 Female 5/16/2006 Switzerland
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2004 44 Female 291 lb 5/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Congestion Death 41 Female 6/16/2006 Other Health Professional United States
Primary
Secondary
Urticaria Other Serious 5/25/2006 42 Female 270 lb 7/20/2006 United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2000 Female 310 lb 7/25/2006 United States
Primary
Concomitant
Weight Decreased Other Serious Female 7/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 3/18/1996 78 Female 9/28/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 50 Male 10/20/2006 Physician India
Primary
Secondary
Concomitant
Renal Tubular Acidosis Hospitalization 35 Female 10/23/2006 Physician United States
Primary
Concomitant
Polydipsia Other Serious 6/20/2005 79 Female 150 lb 11/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 48 Male 11/22/2006 Other Health Professional Spain
Primary
Secondary
Ventricular Fibrillation Hospitalization Male 12/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Hospitalization 65 Male 12/19/2006
Primary
Secondary
Concomitant
Somnolence Other Serious 22 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 35 Female 1/4/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious Female 1/4/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious 22 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Somnolence Other Serious 20 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Intentional Overdose Other Serious 20 Female 1/5/2007 Consumer Ireland
Primary
Secondary
Spinal Epidural Haemorrhage Hospitalization 11/30/2006 80 Female 1/17/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Spinal Epidural Haemorrhage Hospitalization 11/30/2006 80 Female 1/19/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Myoclonus Hospitalization 5/17/2006 63 Male 10/10/2006 Physician United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 1/25/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Pyroglutamate Increased Hospitalization 50 Male 3/23/2007 Physician India
Primary
Secondary
Concomitant
Suicide Attempt Death 41 Female 4/3/2007
Primary
Secondary
Umbilical Hernia Hospitalization 8/12/2006 37 Male 4/5/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Acute Life Threatening 2/6/2007 79 Male 187 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 80 Female 4/17/2007 Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 50 Male 5/8/2007 Other Health Professional India
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 9/21/1976 7 Male 7/6/2007 Physician France
Primary
Secondary
Concomitant
Migraine Hospitalization 4/23/2007 49 Male 7/23/2007 Consumer Canada
Primary
Concomitant
Hiatus Hernia Death 3/28/2006 Female 139 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/9/2005 40 Female 8/7/2007 Physician Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/9/2005 40 Female 9/11/2007 Physician Brazil
Primary
Concomitant
Pregnancy Other Serious 7/26/2007 24 Female 115 lb 9/12/2007 Physician Colombia
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 37 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/4/2007 13 Male 88 lb 9/17/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/9/2005 40 Female 9/27/2007 Physician Brazil
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 9/4/2007 13 Male 88 lb 9/24/2007 Physician Japan
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Viral Infection Hospitalization 2/22/2005 35 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/9/2005 40 Female 10/11/2007 Physician Brazil
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 35 Male 10/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening Female 10/31/2007 Physician Germany
Primary
Secondary
Nausea Hospitalization 3/14/2007 61 Female 197 lb 4/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pulse Pressure Decreased 1/20/2006 54 Male 160 lb 1/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 20 Male 99 lb 1/8/2008 Other Health Professional United Kingdom
Primary
Interacting
Encephalopathy Other Serious 20 Male 99 lb 12/29/2007 United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 20 Male 99 lb 1/7/2008 Physician United Kingdom
Primary
Secondary
Road Traffic Accident Death 1/25/2007 36 Male 217 lb 10/31/2007 Other Health Professional United States
Primary
Secondary
Respiratory Failure Life Threatening 42 Male 99 lb 1/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Proctocolitis Hospitalization 10/31/2007 55 Female 1/18/2008 Other Health Professional France
Primary
Concomitant
Syncope Other Serious 2/2/2007 70 Female 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 65 Male 2/6/2008 Other Health Professional New Zealand
Primary
Concomitant
Overdose Hospitalization 20 Male 99 lb 2/21/2008 United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 2/1/2007 Female 216 lb 3/11/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 1 Male 3/28/2008 Netherlands
Primary
Secondary
Concomitant
Overdose Death 1/1/2007 33 Female 4/16/2008 Sweden
Primary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 46 5/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 8/18/2002 49 Male 5/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/2/2008 Consumer United Kingdom
Primary
Concomitant
No Adverse Event 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 6/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 11/29/2007 Male 6/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 11/3/2007 Male 209 lb 6/11/2008 Physician Australia
Primary
Secondary
Concomitant
Trigeminal Nerve Disorder Hospitalization 39 Female 6/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 9/4/2007 13 Male 88 lb 6/26/2008 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/15/2008 Male 48 lb 7/3/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Disorder Other Serious 2/1/2008 37 Female 181 lb 7/8/2008 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 4/26/2008 Female 7/8/2008 Physician Germany
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Male 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/15/2008 Male 48 lb 7/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 34 Female 8/28/2008 Other Health Professional Bulgaria
Primary
Concomitant
Rash Maculo-papular Hospitalization 23 Male 8/28/2008 Other Health Professional Bulgaria
Primary
Concomitant
Pain 9/1/2007 65 Female 159 lb 9/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 10/6/2008 Consumer United Kingdom
Primary
Secondary
Hyperammonaemia Other Serious 7/21/2008 Male 10/7/2008 Physician France
Primary
Concomitant
Treatment Noncompliance Hospitalization 35 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Death 12/30/2007 26 Female 11/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/10/2008 71 Male 11/6/2008 Netherlands
Primary
Concomitant
Pneumonia Other Serious 10/27/2008 Male 11/11/2008 Consumer United Kingdom
Primary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 11/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 12/1/2008 Consumer United Kingdom
Primary
Secondary
Lipoatrophy Other Serious 10/1/2008 33 Male 12/2/2008 Brazil
Primary
Concomitant
Visual Acuity Reduced Disability 46 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/27/2008 Male 12/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 23 Male 11/24/2008 Netherlands
Primary
Concomitant
Gastrointestinal Stromal Tumour Hospitalization 7/31/2008 Female 121 lb 12/5/2008 United Kingdom
Primary
Concomitant
Visual Acuity Reduced Disability 46 12/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/27/2008 Male 12/11/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 9/7/2008 Female 12/12/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Disability 46 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/27/2008 Male 12/18/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 46 12/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 46 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 38 Male 12/24/2008 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 12/30/2008 Female 124 lb 1/8/2009 Canada
Primary
Concomitant
Dyspnoea Other Serious 1/1/2008 14 Female 1/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 12/30/2008 Female 124 lb 1/13/2009 Canada
Primary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 1/14/2009 Physician United Kingdom
Primary
Secondary
Pneumonia Other Serious 12/3/2008 60 Female 1/12/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 1/21/2009 Consumer United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 12/26/2006 72 Female 1/22/2009 Physician United Kingdom
Primary
Secondary
Cerebrovascular Accident Hospitalization 12/26/2006 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 12/26/2006 72 Female 1/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/3/2008 60 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Suicidal Ideation Hospitalization 12/30/2008 Female 124 lb 1/27/2009 Canada
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 12/26/2006 72 Female 1/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 12/26/2006 72 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 1/23/2009 United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/7/2009 72 Female 1/31/2009 Other Health Professional Germany
Primary
Secondary
Suicidal Ideation Hospitalization 12/30/2008 Female 124 lb 2/2/2009 Canada
Primary
Concomitant
Dyspnoea Hospitalization 12/26/2006 72 Female 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Off Label Use Hospitalization 12/26/2006 72 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Multiple Drug Overdose Intentional Death 38 Male 2/27/2009 United States
Primary
Secondary
Suicide Attempt Other Serious 14 Female 3/5/2009 Netherlands
Primary
Secondary
Visceral Congestion Death 36 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 14 Female 3/17/2009 Netherlands
Primary
Secondary
Drug Toxicity Death 36 Female 4/3/2009
Primary
Secondary

Drug Data