Acetaminophen combined with Acetylcysteine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 2/2/2006 Physician Spain
Primary
Secondary
Concomitant
Multiple Drug Overdose Life Threatening 37 Female 1/26/2006
Primary
Secondary
Petechiae Hospitalization 1/1/2005 84 Male 2/16/2006 France
Primary
Secondary
Concomitant
Intracranial Venous Sinus Thrombosis Life Threatening 12/7/2005 56 Male 2/24/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/17/2006 34 Female 110 lb 2/8/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Shoulder Pain Hospitalization 1/1/2003 36 Male 287 lb 3/2/2006 Physician Germany
Primary
Concomitant
Urine Output Decreased Other Serious 12/2/2005 80 Female 3/15/2006 Sweden
Primary
Secondary
Concomitant
Infection Hospitalization 11/4/2005 65 Male 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Shoulder Pain Hospitalization 1/1/2003 36 Male 287 lb 5/9/2006 Physician Germany
Primary
Concomitant
Lymphoma Hospitalization 10/19/2000 77 Male 5/19/2006 Physician Sweden
Primary
Concomitant
Swelling Face Hospitalization 4/8/2006 18 Female 6/21/2006 Consumer Sweden
Primary
Secondary
Swelling Face Hospitalization 4/8/2006 18 Female 6/29/2006 Consumer Sweden
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/30/2004 Female 7/20/2006 Other Health Professional Sweden
Primary
Concomitant
Lung Disorder Hospitalization 3/23/2005 26 Male 7/25/2006 Physician Germany
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Disability 1/4/2006 0 Male 7/24/2006 United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/4/2006 Other Health Professional Sweden
Primary
Concomitant
Incision Site Haematoma Other Serious 11/19/2005 41 Male 8/2/2006 Turkey
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 8/25/2006 Other Health Professional Sweden
Primary
Concomitant
Post Procedural Complication Other Serious 12/12/2005 72 Female 132 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 4/1/2006 56 Female 9/14/2006 Other Health Professional Sweden
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 77 Female 9/19/2006 United Kingdom
Primary
Secondary
Concomitant
Muscle Haemorrhage Death 7/1/2006 78 Male 132 lb 10/6/2006 Physician Portugal
Primary
Concomitant
Respiratory Tract Infection Hospitalization 4/1/2006 56 Female 9/28/2006 Other Health Professional Sweden
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/30/2004 51 Female 10/12/2006 Physician Sweden
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/17/2006 83 Male 175 lb 9/29/2006 Physician Germany
Primary
Concomitant
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/17/2006 83 Male 175 lb 10/18/2006 Physician Germany
Primary
Concomitant
Lymphadenopathy Other Serious 6/1/2006 44 Male 11/7/2006 Physician France
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Kaposi's Sarcoma Other Serious 6/1/2006 44 Male 11/17/2006 Physician France
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 1/26/2006 Female 12/15/2006 Consumer France
Primary
Concomitant
Interacting
Transaminases Increased Other Serious 18 Female 12/18/2006 Other Health Professional United States
Primary
Secondary
Osteopenia Hospitalization 8/4/2005 61 Male 12/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Intentional Overdose Other Serious Male 1/4/2007 Consumer Ireland
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/30/2004 Female 3/8/2007 Other Health Professional Sweden
Primary
Concomitant
Stridor Disability 1/4/2006 0 Male 3/8/2007 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/25/2007 67 Female 91 lb 3/16/2007 Physician United States
Primary
Concomitant
Urticaria Hospitalization 4/19/2007 27 Female 5/9/2007 Consumer Sweden
Primary
Secondary
Concomitant
Arrhythmia Other Serious 10/4/2006 72 Female 6/19/2007 Other Health Professional Sweden
Primary
Concomitant
Ventricular Tachycardia Death 6/6/2007 65 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Anaphylactoid Reaction Hospitalization 2/15/2007 16 Male 7/12/2007 Australia
Primary
Concomitant
Sepsis Hospitalization 2/25/2007 67 Female 91 lb 7/18/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 2/25/2007 67 Female 91 lb 7/26/2007 Physician United States
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 5/3/2007 66 Female 7/10/2007 Other Health Professional United States
Primary
Concomitant
Gun Shot Wound Death 5/22/2006 Male 11/2/2007 Pharmacist France
Primary
Secondary
Concomitant
Epistaxis Hospitalization 9/5/2007 Female 11/29/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Scratch Hospitalization 10/29/2007 75 Female 12/18/2007 Consumer France
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/29/2007 Male 12/19/2007 Consumer Netherlands
Primary
Concomitant
Visual Disturbance Other Serious 9/29/2007 75 Male 12/27/2007 Consumer Netherlands
Primary
Concomitant
Visual Disturbance Other Serious 9/29/2007 75 Male 187 lb 1/22/2008 Consumer Netherlands
Primary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 Male 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 Male 1/30/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 62 Male 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 1/1/2004 63 Male 1/29/2008 Denmark
Primary
Concomitant
Toxic Epidermal Necrolysis Death 8/6/2004 62 Male 2/1/2008 Physician Germany
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 8/31/2007 Male 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/16/2005 89 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/16/2005 Female 3/3/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 3/16/2005 Female 3/4/2008 Consumer
Primary
Secondary
Concomitant
Seizure Anoxic Hospitalization 12/4/2007 87 Male 3/18/2008 Other Health Professional Sweden
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 2/12/2008 68 Female 3/26/2008 Consumer Thailand
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 67 Female 5/7/2008 Ireland
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/25/2008 68 Female 5/19/2008 Consumer Thailand
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/19/2007 67 Female 5/21/2008 Ireland
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 58 Female 159 lb 6/9/2008 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 2/15/2008 83 Male 6/16/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/15/2008 83 Male 6/27/2008
Primary
Secondary
Concomitant
Syncope Other Serious 4/30/2008 81 Male 6/27/2008 Sweden
Primary
Concomitant
Renal Failure Hospitalization 2/15/2008 83 Male 7/3/2008
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/15/2008 83 Male 7/9/2008
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 78 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 21 Female 154 lb 7/30/2008 Other Health Professional Germany
Primary
Secondary
Pseudomonal Sepsis Hospitalization 3/13/2008 9 Male 35 lb 8/19/2008 Physician Brazil
Primary
Concomitant
Yellow Skin Hospitalization 5/7/2006 Male 168 lb 9/9/2008 Belgium
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 58 Female 159 lb 9/17/2008 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Fatigue Death 11/3/2005 73 Male 10/13/2008 Physician Poland
Primary
Secondary
Concomitant
Stupor Other Serious 31 Male 256 lb 11/6/2008 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 11/16/2008 48 Female 176 lb 11/20/2008 Physician Germany
Primary
Secondary
Headache Hospitalization 11/7/2008 71 Female 137 lb 11/19/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 11/16/2008 59 Female 183 lb 12/1/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 11/16/2008 59 Female 183 lb 11/27/2008 Sweden
Primary
Concomitant
Headache Hospitalization 11/7/2008 71 Female 126 lb 12/15/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Stupor Other Serious 31 Male 256 lb 12/22/2008 Physician Germany
Primary
Secondary
Hepatic Enzyme Increased Other Serious 11/16/2008 59 Female 183 lb 1/22/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/27/2008 55 Female 1/23/2009 Physician United Kingdom
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 11/16/2008 59 Female 183 lb 1/23/2009 Sweden
Primary
Concomitant
Respiratory Acidosis Hospitalization 80 Male 1/26/2009 United Kingdom
Primary
Concomitant
Prostatic Mass Hospitalization 11/4/2007 77 Male 3/17/2009 Korea, Republic Of
Primary
Concomitant
Thrombophlebitis Hospitalization 2/23/2009 75 Male 90 lb 4/21/2009 Other Health Professional Belgium
Primary
Concomitant
Musculoskeletal Pain Hospitalization 11/4/2007 77 Male 4/22/2009 Korea, Republic Of
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Femur Fracture Life Threatening 6/9/2009 75 Female 7/7/2009 Other Health Professional Norway
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 6/17/2009 0 Female 19 lb 7/7/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 2/1/2009 14 Male 49 lb 7/7/2009 Physician Brazil
Primary
Concomitant
Sleep Disorder Other Serious 7/20/2009 Male 8/4/2009 Physician Sweden
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 167 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 6/22/2009 62 Male 172 lb 9/3/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 2/23/2009 75 Male 201 lb 9/21/2009 Other Health Professional Belgium
Primary
Concomitant
Wheezing Other Serious 7/1/2009 97 10/30/2009 Other Health Professional Sweden
Primary
Concomitant
Cerebral Infarction Other Serious 6/2/2009 84 10/30/2009 Other Health Professional Sweden
Primary
Concomitant
Oedema Peripheral Other Serious Female 176 lb 11/2/2009 Other Health Professional Sweden
Primary
Concomitant
Fatigue Hospitalization 10/1/2008 68 Male 12/10/2009 Sweden
Primary
Secondary
Concomitant
Haematoma Other Serious 11/19/2009 25 Male 193 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 176 lb 12/30/2009 Other Health Professional Sweden
Primary
Concomitant
Drug Toxicity Death 59 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Medication Error Death 59 Male 1/26/2010 Other Health Professional United States
Primary
Secondary
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 1/21/2010 United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/28/2009 81 Male 141 lb 1/28/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Respiratory Failure Other Serious 11/14/2009 56 Female 136 lb 2/12/2010 United States
Primary
Secondary
Concomitant
Medication Error Death 59 Male 2/26/2010 Other Health Professional United States
Primary
Secondary
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Medication Error Death 59 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Pancreatitis Acute Life Threatening 2/16/2010 25 Female 3/19/2010 Other Health Professional France
Primary
Concomitant
Pancreatitis Acute Life Threatening 2/16/2010 25 Female 3/23/2010 Other Health Professional France
Primary
Concomitant
Mood Altered Other Serious Male 3/26/2010 Physician Spain
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 2/25/2010 42 Male 5/7/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 12/2/2008 47 Female 5/7/2010 Physician Germany
Primary
Secondary
Concomitant
Urticaria Hospitalization 2/25/2010 42 Male 5/13/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 2/28/2010 56 Male 5/13/2010 Physician Sweden
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 0 Female 10 lb 6/28/2010 Other Health Professional Spain
Primary
Secondary
Stomatitis Other Serious 9/17/2007 70 Female 6/30/2010 Physician Germany
Primary
Secondary
Concomitant
Rash Other Serious 2/1/2008 26 Female 170 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 7/2/2010 Pharmacist United States
Primary
Concomitant
Intentional Overdose Other Serious Female 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Hyponatraemia Life Threatening 0 Female 10 lb 7/12/2010 Other Health Professional Spain
Primary
Secondary
Renal Failure Acute Life Threatening 10/22/2008 89 Female 165 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 1/15/2010 63 Male 187 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Death Male 7/15/2010 Physician Singapore
Primary
Concomitant
Weight Decreased Other Serious 4/14/2009 67 Female 7/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 2/25/2010 42 Male 7/30/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 4/13/2008 86 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 44 Female 172 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Twin Pregnancy Other Serious 1/2/2010 32 Female 114 lb 8/20/2010 United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/19/2007 58 Male 8/23/2010 Physician Canada
Primary
Secondary
Concomitant
Prothrombin Level Decreased Hospitalization 2/19/2010 86 Male 8/17/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rash Other Serious 2/1/2008 26 Female 170 lb 8/26/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Haemorrhage Hospitalization 7/1/2010 75 Male 179 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data