Abacavir combined with Efavirenz

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumocystis Jiroveci Pneumonia Hospitalization 10/15/2004 47 Male 1/20/2006 Japan
Primary
Concomitant
Vitamin D Increased Other Serious 39 Male 1/27/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Osteomalacia Other Serious 39 Male 1/27/2006 United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/13/2002 56 Male 1/31/2006 Physician Japan
Primary
Secondary
Concomitant
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/17/2003 53 Male 2/24/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/28/2006 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 1/13/2006 47 Male 3/7/2006 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 1/13/2006 47 Male 3/7/2006 Physician Spain
Primary
Concomitant
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Load Increased Hospitalization 1/30/2002 44 Male 110 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2001 58 Male 3/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/17/2001 58 Male 4/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 3/27/2006 29 Female 99 lb 4/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 3/27/2006 29 Female 98 lb 4/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Social Avoidant Behaviour Other Serious 11 Male 64 lb 4/28/2006 Consumer Spain
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 1/27/2006 43 Male 141 lb 5/4/2006 Physician Belgium
Primary
Concomitant
Urinary Tract Obstruction Required Intervention 4/1/2006 Male 5/8/2006 Consumer United States
Primary
Concomitant
Urinary Tract Obstruction Required Intervention 4/1/2006 Male 5/23/2006 Consumer United States
Primary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 6/13/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 10/15/2004 47 Male 7/7/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/25/2006 46 Male 137 lb 7/10/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 7/21/2006 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 9/26/2005 Male 8/10/2006 Physician Japan
Primary
Concomitant
Hallucination Other Serious 45 Male 8/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/6/2004 Female 8/21/2006 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 12/1/2003 31 Male 8/21/2006 Consumer United States
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 123 lb 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/3/2003 31 Male 8/22/2006 Consumer United States
Primary
Secondary
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Primary Adrenal Insufficiency Hospitalization 12/1/2005 61 Male 11/4/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/17/2001 58 Male 11/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Floaters Other Serious 9/14/2006 50 Male 11/13/2006 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/22/2006 Male 12/1/2006 Physician Chile
Primary
Concomitant
Phlebitis Hospitalization 1/1/1999 55 Male 12/6/2006 Consumer France
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 1/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 9/22/2006 Male 1/19/2007 Physician Chile
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 61 Male 101 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 7/19/2006 43 Male 2/22/2007 Other Health Professional France
Primary
Secondary
Concomitant
Primary Adrenal Insufficiency Hospitalization 12/1/2005 61 Male 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 46 Male 178 lb 3/21/2007 Consumer Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 46 Male 178 lb 3/29/2007 Consumer Germany
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 3/18/2000 24 Male 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 34 Female 6/1/2007 Consumer Canada
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 6/6/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 6/1/1999 31 Male 8/3/2007 Physician Spain
Primary
Secondary
Urticaria Hospitalization 6/25/2007 7 Female 8/7/2007 Physician Uganda
Primary
Secondary
Concomitant
Rash Hospitalization 7/13/2007 4 Male 8/9/2007 Physician Uganda
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 7/13/2007 3 Male 8/13/2007 Physician Uganda
Primary
Secondary
Concomitant
Urticaria Other Serious 7/13/2007 3 Male 8/22/2007 Physician Uganda
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 7/13/2007 4 Male 8/27/2007 Physician Uganda
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/17/2007 5 Female 9/4/2007 Physician Uganda
Primary
Secondary
Concomitant
Uveitis Other Serious 7/8/2007 Male 9/4/2007 Physician United States
Primary
Concomitant
Aplasia Cutis Congenita Congenital Anomaly Female 7 lb 9/14/2007
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 36 Male 11/19/2007 Consumer United States
Primary
Secondary
Pneumonia Hospitalization 7/3/2002 Male 2/26/2008 Japan
Primary
Secondary
Concomitant
Myocarditis Hospitalization 9/22/2007 44 Male 2/29/2008 Physician Spain
Primary
Secondary
Concomitant
Restlessness Hospitalization 12/17/2001 58 Male 3/5/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/6/2008 9 Female 3/11/2008 Physician Uganda
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/4/2008 9 Female 3/14/2008 Physician Uganda
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/15/2008 9 Female 3/21/2008 Physician Uganda
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 3/21/2008 Physician Uganda
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 50 Male 3/31/2008
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 4/2/2008 Physician Uganda
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/15/2008 9 Female 4/7/2008 Physician Uganda
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 4/7/2008 Physician Uganda
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 4/30/2008 Physician Uganda
Primary
Secondary
Concomitant
Nausea Hospitalization 9/13/2002 Male 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 35 Male 5/8/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 5/22/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Osteonecrosis Disability 10/1/2007 Male 194 lb 5/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Death 11/1/2007 Male 6/16/2008 Physician Japan
Primary
Concomitant
Drug Resistance Other Serious 6/18/2008 Spain
Primary
Concomitant
Drug Resistance Other Serious 6/18/2008 Spain
Primary
Concomitant
Renal Tubular Necrosis Other Serious 3/17/2008 Female 6/20/2008 Physician United States
Primary
Concomitant
Interacting
Abortion Spontaneous Other Serious 6/21/2007 Female 7/8/2008 United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 6/21/2007 26 Female 7/10/2008 Other Health Professional Uganda
Primary
Secondary
Viral Hepatitis Carrier Other Serious 7/1/2002 60 Male 7/16/2008 Physician Japan
Primary
Secondary
Cytomegalovirus Infection Death 11/1/2007 Male 7/22/2008 Physician Japan
Primary
Concomitant
Lipodystrophy Acquired Other Serious 13 Female 7/30/2008 Consumer Spain
Primary
Secondary
Lipodystrophy Acquired Other Serious 13 Female 8/7/2008 Spain
Primary
Secondary
Pallor Other Serious 9/1/2008 8 Male 9/8/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/1/2008 8 Male 9/15/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 37 Female 9/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Tachycardia Other Serious 9/1/2008 8 Male 9/30/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 13 Female 9/30/2008 Spain
Primary
Secondary
Blood Hiv Rna Increased Other Serious Male 10/31/2008 Other Health Professional United States
Primary
Secondary
Rash Other Serious 11/5/2008 Other Health Professional Germany
Primary
Secondary
Varices Oesophageal Other Serious Female 12/11/2008
Primary
Secondary
Syncope Hospitalization 6/1/2008 64 Male 1/12/2009 Physician Argentina
Primary
Concomitant
Osteomalacia Other Serious 45 Female 1/15/2009 Other Health Professional Germany
Primary
Secondary
Interacting
Myocardial Infarction Other Serious Female 2/12/2009 Consumer United States
Primary
Secondary
Varices Oesophageal Hospitalization 11/1/2008 Male 2/27/2009 Physician United States
Primary
Secondary
Varices Oesophageal Hospitalization 1/1/2001 Male 3/5/2009 Physician United States
Primary
Secondary
Transaminases Increased Other Serious 9/29/2000 40 Male 3/6/2009 Physician Spain
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 1/1/2001 Male 3/11/2009 Physician United States
Primary
Secondary
Transplant Rejection Other Serious 9 Male 3/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Life Threatening 2/11/2009 Male 35 lb 3/27/2009 Physician Zimbabwe
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 9 Male 3/30/2009 Other Health Professional Nigeria
Primary
Secondary
Renal Disorder Hospitalization 9 Male 3/24/2009
Primary
Secondary
Transplant Rejection Other Serious 9 Male 3/30/2009 United Kingdom
Primary
Secondary
Transplant Rejection Other Serious 1/1/2008 9 Male 4/2/2009 United Kingdom
Primary
Secondary
Vomiting Life Threatening 2/11/2009 Male 35 lb 4/8/2009 Physician Zimbabwe
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 1/17/2009 56 Male 170 lb 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Myocardial Infarction Life Threatening 1/17/2009 56 Male 170 lb 4/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 9 Male 4/22/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Pyrexia Hospitalization 7/17/2007 Female 40 lb 4/28/2009 Physician Uganda
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 9 Male 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Myocardial Infarction Life Threatening 1/17/2009 56 Male 170 lb 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 7/17/2007 Female 40 lb 5/7/2009 Physician Uganda
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 9 Male 5/8/2009 Other Health Professional Nigeria
Primary
Secondary
Skin Papilloma Other Serious 38 Female 5/8/2009 Consumer United States
Primary
Secondary
Osteomalacia Other Serious 45 Female 5/26/2009 Other Health Professional Italy
Primary
Secondary
Interacting

Drug Data