Abacavir combined with Didanosine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Umbilical Cord Around Neck Other Serious 38 Female 1/5/2006 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 44 Male 1/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/15/2004 47 Male 1/20/2006 Japan
Primary
Concomitant
Somnolence Hospitalization 4/17/2005 Male 1/24/2006 Brazil
Primary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 1/30/2006 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 2/1/2006 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 2/2/2006 Brazil
Primary
Concomitant
Somnolence Hospitalization 4/17/2005 Male 2/2/2006 Brazil
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/13/2002 56 Male 1/31/2006 Physician Japan
Primary
Secondary
Concomitant
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Somnolence Hospitalization 4/17/2005 Male 2/13/2006 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 2/13/2006 Brazil
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 2/14/2006 Brazil
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Intra-uterine Death Other Serious 1/1/2002 32 Female 2/28/2006
Primary
Secondary
Concomitant
Pre-eclampsia Other Serious 1/1/2003 33 Female 2/28/2006
Primary
Secondary
Therapy Non-responder Hospitalization 15 Male 2/28/2006 Physician United Kingdom
Primary
Secondary
Trisomy 21 Congenital Anomaly 10/1/2005 0 3/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 56 Female 152 lb 3/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 44 Male 3/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/12/2003 Male 195 lb 4/12/2006 Canada
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 56 Female 152 lb 4/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 50 Male 4/28/2006 United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 10/27/2005 56 Female 152 lb 5/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/9/2004 Male 5/18/2006 United States
Primary
Concomitant
Cushing's Syndrome Other Serious Female 6/2/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 8/9/2004 Male 6/14/2006 United States
Primary
Concomitant
Varices Oesophageal Other Serious 1/1/2003 65 Male 6/9/2006 Physician France
Primary
Concomitant
Pancreatitis Other Serious 38 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 66 Female 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 66 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Leukopenia Other Serious 7/5/1999 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 7/6/2006
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 10/15/2004 47 Male 7/7/2006 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 51 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 9/26/2005 Male 8/10/2006 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 123 lb 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Toxoplasmosis Other Serious 1/4/2005 44 Female 8/25/2006 Physician Uganda
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 1/4/2005 44 Female 8/25/2006 Physician Uganda
Primary
Secondary
Concomitant
Drug Ineffective Death 6/30/2004 38 Male 8/31/2006 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2005 Male 116 lb 9/1/2006 Physician Japan
Primary
Concomitant
Osteoporosis Other Serious 2/1/2003 Male 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Renal Failure Death 8/9/2004 Male 10/10/2006 United States
Primary
Concomitant
Hypoxia Hospitalization 5/2/2003 Male 10/12/2006 Germany
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Osteonecrosis Hospitalization 6/23/2005 Female 148 lb 10/19/2006 Ireland
Primary
Concomitant
Weight Decreased Other Serious Female 10/30/2006
Primary
Secondary
Non-hodgkin's Lymphoma Hospitalization 9/27/2006 40 Male 11/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 1/29/2006 Male 165 lb 11/14/2006 Brazil
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/27/2006 40 Male 11/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 9/22/2006 Male 12/1/2006 Physician Chile
Primary
Concomitant
Weight Decreased Other Serious Female 12/6/2006
Primary
Secondary
Splenic Rupture Hospitalization 41 Male 12/15/2006
Primary
Secondary
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 41 Male 12/29/2006
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/4/2007 Germany
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/8/2007 Germany
Primary
Secondary
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 1/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 9/22/2006 Male 1/19/2007 Physician Chile
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 59 Male 104 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 49 Male 128 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 10/16/2006 Male 154 lb 3/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 7/9/1998 43 Male 3/15/2007 Other Health Professional United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased Life Threatening 6/22/1998 41 Male 3/16/2007 Other Health Professional United States
Primary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 5/16/2007 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 5/16/2007 Brazil
Primary
Concomitant
Muscle Spasms Other Serious 43 Female 6/4/2007 Consumer Canada
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 6/6/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 68 Female 6/7/2007 Pharmacist Canada
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Dyslipidaemia Death 3/23/2007 48 Male 134 lb 7/6/2007 Physician Romania
Primary
Concomitant
Abortion Spontaneous Hospitalization 6/27/2007 Female 111 lb 7/11/2007 Argentina
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Abortion Spontaneous Hospitalization 6/27/2007 Female 111 lb 7/13/2007 Argentina
Primary
Concomitant
Abortion Spontaneous Hospitalization 6/27/2007 Female 7/19/2007 Argentina
Primary
Secondary
Concomitant
Dyslipidaemia Death 3/23/2007 Male 134 lb 7/20/2007 Physician Romania
Primary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 6/1/1999 31 Male 8/3/2007 Physician Spain
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/14/2007 Other Health Professional United States
Primary
Secondary
Urinary Retention Other Serious 8/20/2007 40 Male 112 lb 9/14/2007 Colombia
Primary
Concomitant
Joint Dislocation Congenital Anomaly Female 2 lb 9/17/2007 United States
Primary
Secondary
Joint Dislocation Other Serious Female 2 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Joint Dislocation Congenital Anomaly Female 20 lb 9/17/2007 United States
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly Female 2 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Joint Dislocation Congenital Anomaly Female 20 lb 9/21/2007 United States
Primary
Secondary
Concomitant
Joint Dislocation Congenital Anomaly Female 2 lb 9/25/2007 United States
Primary
Secondary
Joint Dislocation Other Serious Female 2 lb 9/27/2007 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 8/20/2007 40 Male 112 lb 9/28/2007 Colombia
Primary
Concomitant
Mydriasis Hospitalization 10/21/2007 Female 142 lb 11/2/2007 Chile
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 49 Male 11/28/2007
Primary
Secondary
Concomitant
Mydriasis Hospitalization 10/21/2007 Female 142 lb 12/6/2007 Chile
Primary
Concomitant
Drug Level Decreased Other Serious 49 Male 12/6/2007 Germany
Primary
Concomitant
Interacting
Abortion Spontaneous Other Serious 42 Female 12/12/2007 Physician United States
Primary
Secondary
Renal Failure Acute Hospitalization 6/1/2004 65 Female 12/26/2007 Spain
Primary
Concomitant
Interacting
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 2/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Hospitalization 7/3/2002 Male 2/26/2008 Japan
Primary
Secondary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Pharyngeal Ulceration Other Serious 3/4/2008 Female 105 lb 3/19/2008 Chile
Primary
Concomitant
Weight Decreased Other Serious Female 3/19/2008
Primary
Secondary
Pharyngeal Ulceration Other Serious 3/4/2008 Female 105 lb 3/26/2008 Chile
Primary
Concomitant
Viral Load Increased Death 3/20/2008 Male 117 lb 3/28/2008 Brazil
Primary
Concomitant
Vomiting Hospitalization 3/5/2008 Male 117 lb 3/28/2008 Brazil
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 9/13/2002 Male 5/1/2008 Physician Japan
Primary
Secondary
Concomitant

Drug Data